BioNTechs und DualityBios Antikörper-Wirkstoff-Konjugat-Kandidat Trastuzumab Pamirtecan zeigte klinisch relevante Wirksamkeit bei Patientinnen mit rezidivierendem HER2-exprimierendem Gebärmutterkrebs Trastuzumab Pamirtecan, ein innovativer gegen HER2 gerichteter Antikörper-Wirkstoff-Konjugat-Kandidat, erreichte den primären Wirksamkeitsendpunkt in einer Phase-2-Kohorte bei stark vorbehandelten Patientinnen mit HER2-exprimierenden rezidivierendem Gebärmutterkrebs, eine Indikation mit hohem ungedecktem medinischem BedarfDie Daten zeigten eine klinisch relevante Anti-Tumor-Aktivität über alle ...
BioNTech and DualityBio’s Antibody-Drug Conjugate Trastuzumab Pamirtecan Demonstrated Clinically Meaningful Efficacy in Patients with HER2-Expressing, Recurrent Endometrial Cancer Trastuzumab pamirtecan, an investigational HER2-targeted antibody-drug conjugate, met the primary efficacy endpoint in a Phase 2 cohort of heavily pre-treated patients with HER2-expressing, recurrent endometrial cancer, an area of high unmet medical needData demonstrated clinically meaningful antitumor activity across all HER2 expression levels and a manageable safety profile, with centrallyi HER2-tested patients ...
A director at IRB - Brasil Resseguros S.A. bought 53,382 shares at 46.000BRL and the significance rating of the trade was 94/100. Is that information sufficient for you to make an investment decision? This report gives details of those trades and adds context and analysis to them such that you can judge whether these trading decisions are ones worth following. Included in the report is a detailed share price chart which plots discretionary trades by all the company's directors over the last tw...
Two Directors at Uniao Pet Participacoes S.A bought 5,961,959 shares at between 3.088BRL and 3.176BRL. The significance rating of the trade was 67/100. Is that information sufficient for you to make an investment decision? This report gives details of those trades and adds context and analysis to them such that you can judge whether these trading decisions are ones worth following. Included in the report is a detailed share price chart which plots discretionary trades by all the company's dire...
A director at Allpark Empreendimentos Participacoes Servicos S.A sold 887,554 shares at 4.600BRL and the significance rating of the trade was 73/100. Is that information sufficient for you to make an investment decision? This report gives details of those trades and adds context and analysis to them such that you can judge whether these trading decisions are ones worth following. Included in the report is a detailed share price chart which plots discretionary trades by all the company's direct...
Two Directors at Companhia Brasileira De Distribuicao sold/bought 48,845,800 shares at between 2.387BRL and 2.920BRL. The significance rating of the trade was 79/100. Is that information sufficient for you to make an investment decision? This report gives details of those trades and adds context and analysis to them such that you can judge whether these trading decisions are ones worth following. Included in the report is a detailed share price chart which plots discretionary trades by all the...
Two Directors at Trisul Sa bought/sold 145,100 shares at between 5.590BRL and 6.570BRL. The significance rating of the trade was 62/100. Is that information sufficient for you to make an investment decision? This report gives details of those trades and adds context and analysis to them such that you can judge whether these trading decisions are ones worth following. Included in the report is a detailed share price chart which plots discretionary trades by all the company's directors over the ...
Three Directors at Hypera SA subscribed to/bought/sold 43,450,831 shares at between 21.250BRL and 25.648BRL. The significance rating of the trade was 91/100. Is that information sufficient for you to make an investment decision? This report gives details of those trades and adds context and analysis to them such that you can judge whether these trading decisions are ones worth following. Included in the report is a detailed share price chart which plots discretionary trades by all the company'...
A director at Ensign Energy Services Inc sold 109,610 shares at 3.599CAD and the significance rating of the trade was 56/100. Is that information sufficient for you to make an investment decision? This report gives details of those trades and adds context and analysis to them such that you can judge whether these trading decisions are ones worth following. Included in the report is a detailed share price chart which plots discretionary trades by all the company's directors over the last two ye...
A director at DHH S.p.A. sold 85,000 shares at 21.500EUR and the significance rating of the trade was 76/100. Is that information sufficient for you to make an investment decision? This report gives details of those trades and adds context and analysis to them such that you can judge whether these trading decisions are ones worth following. Included in the report is a detailed share price chart which plots discretionary trades by all the company's directors over the last two years clearly show...
A director at Montage Gold Corp sold 283,700 shares at 16.501CAD and the significance rating of the trade was 68/100. Is that information sufficient for you to make an investment decision? This report gives details of those trades and adds context and analysis to them such that you can judge whether these trading decisions are ones worth following. Included in the report is a detailed share price chart which plots discretionary trades by all the company's directors over the last two years clea...
A director at Meka Global Makine Imalat Sanayi ve Ticaret A.S sold 11,451,000 shares at 6.785TRY and the significance rating of the trade was 68/100. Is that information sufficient for you to make an investment decision? This report gives details of those trades and adds context and analysis to them such that you can judge whether these trading decisions are ones worth following. Included in the report is a detailed share price chart which plots discretionary trades by all the company's direct...
A director at Anaergia Inc sold 341,600 shares at 2.792CAD and the significance rating of the trade was 85/100. Is that information sufficient for you to make an investment decision? This report gives details of those trades and adds context and analysis to them such that you can judge whether these trading decisions are ones worth following. Included in the report is a detailed share price chart which plots discretionary trades by all the company's directors over the last two years clearly sh...
A director at Nyesa Valores Corporacion SA sold 52,072,000 shares at 0.010EUR and the significance rating of the trade was 90/100. Is that information sufficient for you to make an investment decision? This report gives details of those trades and adds context and analysis to them such that you can judge whether these trading decisions are ones worth following. Included in the report is a detailed share price chart which plots discretionary trades by all the company's directors over the last t...
A director at Soup Holdings Limited bought 15,008,400 shares at 0.060SGD and the significance rating of the trade was 79/100. Is that information sufficient for you to make an investment decision? This report gives details of those trades and adds context and analysis to them such that you can judge whether these trading decisions are ones worth following. Included in the report is a detailed share price chart which plots discretionary trades by all the company's directors over the last two ye...
Seven Directors at Oriental Pearl Media Co L bought 71,800 shares at between 9.060CNY and 9.280CNY. The significance rating of the trade was 51/100. Is that information sufficient for you to make an investment decision? This report gives details of those trades and adds context and analysis to them such that you can judge whether these trading decisions are ones worth following. Included in the report is a detailed share price chart which plots discretionary trades by all the company's directo...
A director at RFA Financial Inc bought 30,200 shares at 25.678CAD and the significance rating of the trade was 66/100. Is that information sufficient for you to make an investment decision? This report gives details of those trades and adds context and analysis to them such that you can judge whether these trading decisions are ones worth following. Included in the report is a detailed share price chart which plots discretionary trades by all the company's directors over the last two years cle...
Communiqué de mise à disposition du rapport financier annuel 2025 POITIERS, le 08 Avril 2026 Communiqué de mise à disposition du Rapport Financier Annuelau 31 décembre 2025 de la Caisse Régionale de Crédit Agricolede la Touraine et du Poitou La Caisse Régionale de Crédit Agricole de la Touraine et du Poitou informe le public que son Rapport Financier Annuel 2025 est disponible sur le site internet depuis ce jour. Conformément à l’article 222-3 du RGAMF, ce rapport inclut : Le rapport sur le gouvernement d’entreprise (établi en application des articles L. 621-18-3 du code monétaire et f...
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