SRNE Sorrento Therapeutics Inc

Scilex Holding Company Announces that its Majority Stockholder, Sorrento Therapeutics, Inc., has Issued a Supplement to its Previously Issued “FAQ” Regarding the Dividend of Scilex Holding Company Common Stock

Scilex Holding Company Announces that its Majority Stockholder, Sorrento Therapeutics, Inc., has Issued a Supplement to its Previously Issued “FAQ” Regarding the Dividend of Scilex Holding Company Common Stock

PALO ALTO, Calif., Feb. 02, 2023 (GLOBE NEWSWIRE) -- Scilex Holding Company (Nasdaq: SCLX) announced that its majority stockholder, Sorrento Therapeutics, Inc. (Nasdaq: SRNE, “Sorrento”) today posted a supplement to its previously issued “Frequently Asked Questions” document under the “Investors” section of its website at regarding its recent dividend to Sorrento stockholders of shares of common stock of Scilex Holding Company held by Sorrento.

The supplement to the FAQs provides notice regarding the Depository Trust and Clearing Corporation’s removal of the contra-CUSIP on Scilex common stock that was distributed as a dividend to Sorrento’s stockholders and provides notice to brokerage firms, banks, dealers and similar organizations listed therein that a dividend confirmation had previously been distributed to such firms by Scilex’s transfer agent and requests that such firms contact Scilex’s transfer agent if they have not received such confirmation. The supplement also reiterates a question related to issues that may arise with respect to the dividend in connection with short positions in Sorrento common stock.

The supplement to the FAQs and related annex are included in this press release and can also be found Scilex’s website

SUPPLEMENT TO

FREQUENTLY ASKED QUESTIONS

REGARDING THE DIVIDEND OF SCILEX HOLDING COMPANY COMMON STOCK BY SORRENTO THERAPEUTICS, INC.

This supplement is a supplement to the Frequently Asked Questions Regarding the Dividend of Scilex Holding Company Common Stock by Sorrento Therapeutics, Inc. (Sorrento) that was issued by Sorrento on January 29, 2023 (the FAQ), a copy of which can be found under the “Investors” section of its website at .

This supplement is being issued to update and supplement the information in the FAQ to notify investors regarding certain matters relating to the dividend and reiterate certain questions and answers from the FAQ. Capitalized terms used in this supplement shall have their respective meetings set forth in the FAQ.

NOTICE OF REMOVAL OF CONTRA-CUSIP BY DTCC

Effective as of February 2, 2023, the Depository Trust and Clearing Corporation has removed the “contra-CUSIP” that it had previously imposed on the Dividend Stock. Any shares of Dividend Stock held by your brokerage firm, bank, dealer or other similar organization for your benefit now bear only Scilex’s CUSIP number, which is 80880W106. If you are entitled to receive Dividend Stock, please contact your brokerage firm, bank, or other similar organization immediately to confirm that the CUSIP number appears on your brokerage statement with respect to your Dividend Stock.

NOTICE TO BROKERAGE FIRMS, BANKS, DEALERS AND OTHER SIMILAR ORGANIZATIONS

If the name of your firm, bank or other similar organization is set forth on Annex B of the FAQ, which Annex B is repeated below for convenience, and your firm, bank or similar organization has not received the Dividend Confirmation that was mailed to your firm, bank or similar organization, please contact Scilex’s transfer agent immediately to obtain a copy of the Dividend Confirmation. Scilex’s transfer agent’s contact information is as follows:

Continental Stock Transfer & Trust Company

Telephone Number: 800-509-5586

Email Address:

Several major brokers have confirmed to Sorrento and Scilex that they are adding the Scilex share positions to the individual brokerage accounts of Sorrento shareholders receiving the Dividend Stock

SUPPLEMENTAL QUESTION AND ANSWER

Q: If I loaned my shares of Sorrento common stock to short sellers or any other party as of the Record Date, am I still entitled to receive Dividend Stock as of the Payment Date? 

A: Only Record Holders as of the Record Date are entitled to receive the Dividend Stock. If you were the Record Holder as of the Record Date and are entitled to receive the Dividend Stock, but have not received the Dividend Stock, you may be entitled to receive Dividend Stock from the short seller or other party who borrowed your shares of Sorrento common stock, whether through the lending programs implemented by your brokerage firm, bank, dealer and other similar organization or otherwise. If you were a Record Holder as of the Record Date and have not received your Dividend Stock, please consult with your financial advisor, broker or other agent immediately to determine how to receive your Dividend Stock.

Annex B

Broker List

Broker NameBroker Address Broker NameBroker Address
ABN AMRO CLEARING CHICAGO LLC175 WEST JACKSON BLVD.

CHICAGO

IL ILLINOIS

60604 US
 Albert Fried & Company LLC45 BROADWAY, 24TH FLOOR

24TH FLOOR

NEW YORK

NY NEW YORK

10006 US
AMALGAMATED BANK275 7TH AVENUE

NEW YORK

NY NEW YORK

10003 US
 AMERICAN ENTERPRISE INVESTMENT SERVICES INC.682 AMERIPRISE FINANCIAL CENTER

MINNEAPOLIS

MN MINNESOTA

55474 US
APEX CLEARING CORPORATION2 GATEWAY CENTER 283-299 MARKET ST

16TH FLOOR

NEWARK

NJ NEW JERSEY

07102-5005 US
 BANK OF AMERICA, NA/GWIM TRUST OPERATIONS901 MAIN STREET

12TH FLOOR

DALLAS

TX TEXAS

23113 US
BANK OF NEW YORK MELLON111 SANDERS CREEK PARKWAY 2ND FLOOR

2ND FLOOR

EAST SYRACUSE

NY NEW YORK

13057 US.
 BARCLAYS CAPITAL INC.DTC CUSTODY PARTICIPANT- NY WINDOW -570 WASHINGTON BLVD (ATTN: ROSA HICKS-MILLER OR ROBERT MENDEZ

JERSEY CITY

NJ NEW JERSEY

07310 US
BARCLAYS CAPITAL INC.DTC CUSTODY PARTICIPANT- NY WINDOW -570 WASHINGTON BLVD (ATTN: ROSA HICKS-MILLER OR ROBERT MENDEZ

JERSEY CITY

NJ NEW JERSEY

07310 US
 BMO CAPITAL MARKETS CORP.3 2ND STREET

12TH FLOOR

JERSEY CITY

NJ NEW JERSEY

07302 US
BMO HARRIS BANK NA/TRUST11270 W PARK PL

MILWAUKEE

WI WISCONSIN

53224 US
 BMO Nesbitt Burns Inc., Toronto250 YONGE STREET, 7TH FLOOR

7TH FLOOR

TORONTO

ON ONTARIO

M5B 2M8 CA CANADA
BNP PARIBAS, NEW YORK BRANCH/BNP PARIBAS PRIME BROKERAGE CUSTODIAN100 WEST 33RD STREET

3RD FLOOR

NEW YORK

NY NEW YORK

10001
 BNP PARIBAS, NEW YORK BRANCH/BNP PARIBAS PRIME BROKERAGE CUSTODIAN100 WEST 33RD STREET

3RD FLOOR

NEW YORK

NY NEW YORK

10001
BNY MELLONPO BOX 392002

500 ROSS STREET

PITTSBURGH

PA PENNSYLVANIA

15262 US
 BNY MELLON/WEALTH MANAGEMENT1 FREEDOM VALLEY DRIVE

OAKS

PA PENNSYLVANIA

19456 US
BNYMELLON111 SANDERS CREEK PARKWAY 2ND FLOOR

2ND FLOOR

EAST SYRACUSE

NY NEW YORK

13057 US
 BNYMELLON/RE BARCLAYS CAPITAL SECURITIES LTD.ONE WALL STREET

NEW YORK

NY NEW YORK

10286
BNYMELLON/RE CACEIS BANK LUXEMBOURG500 Grant St.

BNY Mellon Center

PITTSBURGH

PA PENNSYLVANIA

15258
 BNYMELLON/RE CACEIS BANK, NETHERLANDS111 SANDERS CREEK PARKWAY

EAST SYRACUSE

NY NEW YORK

13057
BNYMELLON/RE CHARLES STANLEY AND COMPANY, LIMITED111 SANDERS CREEK PARKWAY 2ND FLOOR

2ND FLOOR

EAST SYRACUSE

NY NEW YORK

13057 US
 BNYMELLON/RE ETF - ISHARES DTC/NSCC111 SANDERS CREEK PARKWAY

EAST SYRACUSE

NY NEW YORK

13057
BNYMELLON/RE WINTERFLOOD SECURITIES LTD500 Grant St.

BNY Mellon Center

PITTSBURGH

PA PENNSYLVANIA

15258
 BOFA4804 Deer Lake Drive East

FL9-803-04-04- 4th floor

JACKSONVILLE

FL FLORIDA

32246 US
BOFA4804 Deer Lake Drive East

FL9-803-04-04- 4th floor

JACKSONVILLE

FL FLORIDA

32246 US
 BOFA SECURITIES INC4804 Deer Lake Drive East

FL9-803-04-04- 4th floor

JACKSONVILLE

FL FLORIDA

32246 US
BROWN BROTHERS HARRIMAN & CO.140 BROADWAY

ATTN: CORPORATE ACTIONS VAULT

NEW YORK

NY NEW YORK

10005 US
 BROWN BROTHERS HARRIMAN & CO./ETF140 BROADWAY

NEW YORK

NY NEW YORK

10005
CALDWELL SECURITIES LTD./CDS**55 UNIVERSITY AVENUE

SUITE 340

TORONTO

ON ONTARIO

M5J 2H7 CANADA
 CANACCORD GENUITY CORP.609 GRANVILLE ST

VANCOUVER

BC BRITISH COLUMBIA

V7Y 1H2 CA CANADA
CANTOR, FITZGERALD & CO.135 E 57TH ST 5TH FL

NEW YORK

NY NEW YORK

10041 US
 CDS CLEARING AND DEPOSITORY SERVICES INC.100 ADELAIDE STREET WEST

TORONTO

ON ONTARIO

M5H 1S3 CA CANADA
CETERA INVESTMENT SERVICES LLC400 FIRST STREET SOUTH, SUITE 300

SUITE 300

ST. CLOUD

MN MINNESOTA

56302-0283 US
 CHARLES SCHWAB & CO., INC.211 MAIN STREET

SAN FRANCISCO

CA CALIFORNIA

94105 US
CI INVESTMENT SERVICES INC.199 BAY STREET

SUITE 2600

TORONTO

ON ONTARIO

M5L 1E2 CA CANADA
 CIBC WORLD MARKETS INC./CDS**161 BAY STREET 10 FL

TORONTO

ON ONTARIO

M5J 2S8 CA CANADA
CITIBANK, N.A./ETF3800 CITIGROUP CENTER

B2/2

TAMPA

FL FLORIDA

33610
 CITIBANK, NATIONAL ASSOCIATION3800 CITIBANK CENTER TAMPA

BLDG.B FIRST FLOOR ZONE 8

TAMPA

FL FLORIDA

33610-9122 US
CITIGROUP GLOBAL MARKETS, INC.580 CROSSPOINT PARKWAY

GETZVILLE

NY NEW YORK

14068 US
 CLEAR STREET LLC4 World Trade Center, 45th Floor

150 Greenwich Street

NEW YORK

NY NEW YORK

10007
CLEARSTREET IO55 BROADWAY (SUITE 2102)

CORPORATE ACTIONS

NEW YORK

NEW YORK

10006 US
 COMMERCE BANK922 WALNUT STREET

MAIL STOP TBTS-2

KANSAS CITY

MO MISSOURI

64106 US
COR CLEARING LLC9300 UNDERWOOD AVE

SUITE 400

OMAHA

NE NEBRASKA

68114 US
 Credential Securities Inc.800-1111 WEST GEORGIA STREET

VANCOUVER

BC BRITISH COLUMBIA

V6E 4T6 CA CANADA
CREST INTERNATIONAL NOMINEES LIMITED33 CANNON STREET

LONDON

EC4M 5SB GB UNITED KINGDO
 CURVATURE SECURITIES, LLC39 MAIN STREET

CHATHAM

NJ NEW JERSEY

07928 US
D.A. DAVIDSON & CO.8 3RD STREET NORTH

GREAT FALLS

MT MONTANA

59401 US
 DEPOSITO CENTRAL DE VALORES S.A., DEPOSITO DE VALORESAVENIDA APOQUINDO # 4001

FLOOR 12, C.P.

7550162, SANTIAGO

CL CHILE
DESJARDINS SECURITIES INC.1253 McGill College

10TH FLOOR

MONTREAL

QUEBEC

H3B 2Y5 CA CANADA
 DEUTSCHE BANK AG NY/US CUSTODY1251 Avenue Of The Americas

NEW YORK

NY NEW YORK

10020
DEUTSCHE BANK SECURITIES INC.60 WALL STREET

9TH FLOOR

NEW YORK

NY NEW YORK

10005 US
 DRIVEWEALTH, LLC15 EXCHANGE PLACE

10TH FLOOR

JERSEY CITY

NEW JERSEY

07302
E*TRADE CLEARING LLCHARBORSIDE FINANCIAL CENTER

501 PLAZA 11

JERSEY CITY

NJ NEW JERSEY

07311 US
 EDWARD D. JONES & CO., L.P.12555 MANCHESTER ROAD

ST. LOUIS

MO MISSOURI

63131-3729 US
EDWARD D. JONES & CO., L.P.201 PROGRESS PARKWAY

MARYLAND HEIGHTS

MO MISSOURI

63043 US
 FIDELITY CLEARING CANADA ULC/CDS**483 BAY ST.

SOUTH TOWER

TORONTO

ON ONTARIO

M5G2N7 CA CANADA
FIFTH THIRD BANK5001 KINGSLEY DRIVE

MAIL DROP 1MOB28

CINCINNATI

OH OHIO

45227 US
 FOLIO INVESTMENTS, INC.8180 GREENSBORO DRIVE

8TH FLOOR

MCLEAN

VA VIRGINIA

22102 US
FUTU CLEARING INC.12750 Merit Drive

SUITE 475

DALLAS

TX TEXAS

75251
 GMP SECURITIES L.P.145 KING STREET WEST, SUITE 300

11TH FLOOR

TORONTO

ON ONTARIO

MJ5 1J8 CA CANADA
GOLDMAN, SACHS & CO. LLC222 SOUTH MAIN STREET

Attn: Mandatory Corporate Actions

SALT LAKE CITY

UT UTAH

84101 US
 HAYWOOD SECURITIES INC./CDS**200 BURRARD ST

WATERFRONT CENTRE SUITE 700

VANCOUVER

BC BRITISH COLUMBIA

V6C 3L6 CANADA
HILLTOP SECURITIES INC.1201 ELM ST.

35TH FLOOR

DALLAS

TX TEXAS

75270 US
 HRT FINANCIAL LLC150 GREENWICH STREET (ATTN: SETTLEMENT) FOUR WORLD TRADE CENTER

57TH FLOOR

NEW YORK

NY NEW YORK

10007 US
HSBC BANK USA, NA/HSBC CUSTODY & CLEARING SERVICES FOR STOCK LOAN452 FIFTH AVENUE

ATTN: HBUS CCS SETTS

NEW YORK

NY NEW YORK

10018 US
 HSBC BANK USA, NATIONAL ASSOCIATION452 FIFTH AVENUE

ATTN: HBUS CCS SETTS

NEW YORK

NEW YORK

10018 US
INTERACTIVE BROKERS LLC2 PICKWICK PLAZA

2ND FLOOR

GREENWICH

CT CONNECTICUT

06830 US
 J.P. MORGAN CHASE BANK NA/FBO BLACKROCK CTF1111 POLARIS PARKWAY

COLUMBUS

OH OHIO

43240
J.P. MORGAN CLEARING CORP.FOUR CHASE METROTECH CENTER

3RD FLOOR

BROOKLYN

NY NEW YORK

11201 US
 JANNEY MONTGOMERY SCOTT LLC1717 ARCH STREET

17TH FLOOR

PHILADELPHIA

PA PENNSYLVANIA

19103 US
JEFFERIES LLC101 HUDSON STREET, 11th Floor

NEW JERSEY

NJ NEW JERSEY

07302 US
 JPMORGAN CHASE BANK, NATIONAL ASSOCIATIONFOUR CHASE METROTECH CENTER

3RD FLOOR

BROOKLYN

NY NEW YORK

11201 US
JPMORGAN CHASE BANK/EUROCLEAR BANKFOUR CHASE METROTECH CENTER

3RD FLOOR

BROOKLYN

NY NEW YORK

11245 US
 JPMORGAN CHASE BANK/IAFOUR CHASE METROTECH CENTER

3RD FLOOR

BROOKLYN

NY NEW YORK

11201 US
KEYBANK NATIONAL ASSOCIATION4900 TIEDEMAN RD

BROOKLYN

OH OHIO

44144 US
 LAURENTIAN BANK SECURITIES INC.1981 MCGILL COLLEGE AVE.

SUITE 100

MONTREAL

QUEBEC

H3A 3K3 CA CANADA
LPL FINANCIAL LLC4707 EXECUTIVE DRIVE

SAN DIEGO

CA CALIFORNIA

92121 US
 MANUFACTURERS AND TRADERS TRUST COMPANYONE M&T PLAZA

TRUST OPS 8TH FLOOR

BUFFALO

NY NEW YORK

14203 US
MANULIFE SECURITIES INCORPORATED1235 NORTH SERVICE ROAD WEST

OAKVILLE

ON ONTARIO

L6M 2W2 CA CANADA
 MARSCO INVESTMENT CORPORATION101 EISENHOWER PARKWAY

ROSELAND

NJ NEW JERSEY

07068 US
MERRILL LYNCH, PIERCE, FENNER & SMITH INCORPORATED4804 Deer Lake Drive East

FL9-803-04-04- 4th floor

JACKSONVILLE

FL FLORIDA

32246 US
 MIRAE ASSET SECURITIES (USA) INC./STOCK LOAN CONDUIT ACCOUNT810 SEVENTH AVE

37TH FLOOR

NEW YORK

NY NEW YORK

10019
MIRAE ASSET SECURITIES (USA), INC.810 SEVENTH AVE

37TH FLOOR

NEW YORK

NY NEW YORK

10019
 MITSUBISHI UFJ TRUST & BANKING CORPORATION, NEW YORK BRANCH280 PARK AVE

39TH FL-WEST BLDG

NEW YORK

NY NEW YORK

10017
Morgan Stanley1300 THAMES STREET

THAMES STREET WHARF

BALTIMORE

MD MARYLAND

21231 US
 MORGAN STANLEY & CO. LLC1300 THAMES ST.

BALTIMORE

MD MARYLAND
MORGAN STANLEY SMITH BARNEY LLC1 NEW YORK PLAZA

39TH FLOOR

NEW YORK

NY NEW YORK

10004 US
 MURIEL SIEBERT & CO., INC.77 SUMMER STREET

3RD FLOOR

BOSTON

MA MASSACHUSETTS

02210 US
NATIONAL FINANCIAL SERVICES LLC499 WASHINGTON BOULEVARD

5TH FLOOR

JERSEY CITY

NJ NEW JERSEY

07310 US
 NBCN INC.1010 rue De La Gauchetière

Mezzanine 100

MONTREAL

QUEBEC

H3B 5J2 CA CANADA
NOMURA INTERNATIONAL TRUST COMPANY309 WEST 49TH STREET

10TH FLOOR

NEW YORK

NY NEW YORK

10019 US
 ODLUM BROWN LIMITED250 HOWE STREET

SUITE 1100

VANCOUVER

BC BRITISH COLUMBIA

V6C 3R8 CA CANADA
OPPENHEIMER & CO. INC.85 BROAD STREET

NEW YORK

NY NEW YORK

10004 US
 PERSHING LLC1 PERSHING PLAZA

JERSEY CITY

NJ NEW JERSEY

07399 US
PHILLIP CAPITAL INC.141 W. JACKSON BLVD. SUITE 3050

CHICAGO

IL ILLINOIS

60604 US
 PI FINANCIAL CORP.666 BURRARD ST

SUITE 1900

VANCOUVER

BC BRITISH COLUMBIA

V6C 3N1 CA CANADA
PNC BANK, NATIONAL ASSOCIATION4100 W 150TH STREET

ASSET MOVEMENT TEAM 3RD FL, LOCATOR B7-YB17-03-03

CLEVELAND

OH OHIO

44135 US
 PRINCIPAL BANK711 HIGH STREET

DES MOINES

IA IOWA

50392
QUESTRADE INC./CDS**5650 YONGE ST.,

Suite 1700

TORONTO

ON ONTARIO

M2M 4G3 CA CANADA
 Raymond James & Associates, Inc.880 CARILLON PKWY

ST. PETERSBURG

FL FLORIDA

33733-2749 US
RAYMOND JAMES LTD.925 WEST GEORGIA STREET

SUITE 2200

VANCOUVER

BC BRITISH COLUMBIA

V6C 3L2 CA CANADA
 RBC CAPITAL MARKETS, LLC60 SOUTH 6TH ST.

MINNEAPOLIS

MN MINNESOTA

55402 US
RBC DOMINION SECURITIES INC21 COMMERCE COURT SOUTH

2ND FLOOR

TORONTO

ON ONTARIO

M5L 1A7 CANADA
 RELIANCE TRUST COMPANY1100 ABERNATHY RD.

500 NORTHPARK SUITE 400

ATLANTA

GA GEORGIA

30113 US
RELIANCE TRUST COMPANY4900 W. BROWN DEER RD

MILWAUKEE

WI WISCONSIN

53223 US
 ROBERT W. BAIRD & CO. INCORPORATED777 E WISCONSIN AVE

9TH FLOOR

MILWAUKEE

WI WISCONSIN

53202 US
ROBINHOOD SECURITIES, LLC500 COLONIAL CENTER PARKWAY

SUITE 100

LAKE MARY

FL FLORIDA

32746 US
 SAFRA SECURITIES LLC546 5TH AVENUE

NEW YORK

NY NEW YORK

10036 US
SCOTIA CAPITAL (USA) INC.150 KING STREET W

5TH FLOOR

TORONTO

ON ONTARIO

M5H 1J9 CA CANADA
 SEI PRIVATE TRUST COMPANY1 FREEDOM VALLEY DRIVE

OAKS

PA PENNSYLVANIA

19456 US
SEI PRIVATE TRUST COMPANY1 FREEDOM VALLEY DRIVE

OAKS

PA PENNSYLVANIA

19456 US
 SG AMERICAS SECURITIES, LLC480 WASHINGTON BLVD.

20TH FLOOR

JERSEY CITY

NJ NEW JERSEY

07310 US
SSB - BLACKROCK INSTITUTIONAL TRUST50 California Street

San Francisco

CA CALIFORNIA

94163
 SSB - TRUST CUSTODY30 ADELAIDE ST EAST

SUITE 800

TORONTO

ON ONTARIO

M5C 3G6 CA CANADA
SSB&T CO/CLIENT CUSTODY SERVICES1776 HERITAGE DRIVE

NORTH QUINCY

MA MASSACHUSETTS

02171
 STATE STREET BANK & TRUST CO16 WALL STREET

5TH FLOOR

NEW YORK

NY NEW YORK

10005 US
STATE STREET BANK & TRUST COMPANY / ISHARES EUROPE1776 HERITAGE DRIVE

NORTH QUINCY

MA MASSACHUSETTS

02171
 STATE STREET BANK & TRUST/STATE STREET TOTALETF1776 Heritage Drive

NORTH QUINCY

MA MASSACHUSETTS

02717
STATE STREET BANK AND TRUST COMPANY30 ADELAIDE ST EAST

SUITE 800

TORONTO

ON ONTARIO

M5C 3G6 CA CANADA
 STIFEL, NICOLAUS & COMPANY, INCORPORATED501 N BROADWAY

ST. LOUIS

MO MISSOURI

63102 US
STONEX FINANCIAL INC.2 PERIMETER PARK SOUTH

SUITE 100 W

BIRMINGHAM

AL ALABAMA

35243 US
 TD AMERITRADE CLEARING, INC.200 S 108TH AVE

OMAHA

NE NEBRASKA

68154 US
TD WATERHOUSE CANADA INC

ATTN: MANDATORY CORPORATE ACTIONS
77 BLOOR STREET WEST

3RD FLOOR

TORONTO

ON ONTARIO

M5S 1M2 CA CANADA
 TEXAS TREASURY SAFEKEEPING TRUST COMPANY208 E 10TH ST

AUSTIN

TX TEXAS

78701 US
THE BANK OF NEW YORK MELLON500 GRANT STREET

27TH FLOOR

PITTSBURGH

PA PENNSYLVANIA

15258 US
 THE HUNTINGTON NATIONAL BANK7 EASTON OVAL EA4E62

COLUMBUS

OH OHIO

43209 US
THE NORTHERN TRUST COMPANY333 South Wabash Ave, 32nd Floor

Attn: Trade Securities Processing

CHICAGO

IL ILLINOIS

60603 US
 TRADESTATION SECURITIES, INC.120 RIVERSIDE PLAZA

SUITE 1650

CHICAGO

IL ILLINOIS

60606 US
U.S. BANCORP INVESTMENTS, INC.60 LIVINGSTON AVE

EP-MN-WN1B

ST. PAUL

MN MINNESOTA

55107-1419 US
 U.S. BANK N.A./ETF1555 N RIVER CENTER DRIVE

MILWAUKEE

WI WISCONSIN

53212
U.S. BANK NATIONAL ASSOCIATION1555 NORTH RIVERCENTER DRIVE, SUITE 302

SUITE 302

MILWAUKEE

WI WISCONSIN

53212 US
 UBS AG480 WASHINGTON BLVD.

12TH FLOOR

JERSEY CITY

NJ NEW JERSEY

07310 US
UBS FINANCIAL SERVICES INC.1000 HARBOR BOULEVARD

WEEHAWKEN

NJ NEW JERSEY

07086 US
 UBS SECURITIES LLC677 WASHINGTON BLVD

STAMFORD

CT CONNECTICUT

06901 US
UMB BANK, NATIONAL ASSOCIATION928 GRAND BLVD

KANSAS CITY

MO MISSOURI

64106 US
 VANGUARD MARKETING CORPORATION100 VANGUARD BLVD

MALVERN

PA PENNSYLVANIA

19355 US
VELOCITY CLEARING, LLC1301 Route 36

Suite 109 (Attn: Chris Felicetti)

HAZLET

NEW JERSEY

7730 US
 VELOX CLEARING LLC2400 E. KATELLA AVENUE

SUITE 725A

ANAHEIM

CA CALIFORNIA

92806 US
VIRTU AMERICAS LLCONE LIBERTY PLAZA, 165 BROADWAY

5TH FLOOR

NEW YORK

NY NEW YORK

10006 US
 VISION FINANCIAL MARKETS LLC4 HIGH RIDGE PARK

SUITE 100

STAMFORD

CT CONNECTICUT

06905 US
WEDBUSH SECURITIES INC1000 WILSHIRE BLVD

8TH FLOOR

LOS ANGELES

CA CALIFORNIA

90017 US
 WEDBUSH SECURITIES INC.1000 WILSHIRE BLVD.

LOS ANGELES

CA CALIFORNIA

90017 US
WELLS FARGO BANK, N.A./SIG733 MARQUETTE AVE 4TH FLOOR

MAC N9306-04D

MINNEAPOLIS

MN MINNESOTA

55402 US
 WELLS FARGO CLEARING SERVICES LLC1 NORTH JEFFERSON

MAIL CODE: H0006-094

ST. LOUIS

MO MISSOURI

63103 US
WELLS FARGO SECURITIES, LLC1525 WEST W T HARRIS BLVD

CHARLOTTE

NC NORTH CAROLINA

28262 US
 WILSON-DAVIS & CO., INC.236 SOUTH MAIN STREET

SALT LAKE CITY

UT UTAH

84101 US

About Scilex Holding Company 

Scilex Holding Company, a majority-owned by Sorrento Therapeutics, Inc., is an innovative revenue-generating company focused on acquiring, developing, and commercializing non-opioid pain management products for the treatment of acute and chronic pain. Scilex is uncompromising in its focus to become the global pain management leader committed to social, environmental, economic, and ethical principles to responsibly develop pharmaceutical products to maximize quality of life. Results from the Phase III Pivotal Trial C.L.E.A.R Program for SEMDEXA™, its novel, non-opioid product for the treatment of lumbosacral radicular pain (sciatica), were announced in March 2022.  Scilex has applied for breakthrough therapy designation and expects to seek priority review for SEMDEXA™ for the treatment of sciatica.  Scilex targets indications with high unmet needs and large market opportunities with non-opioid therapies for the treatment of patients with moderate to severe pain.  Scilex launched its first commercial product in October 2018, in-licensed a commercial product in June 2022, and is developing its late-stage pipeline, which includes a pivotal Phase 3 candidate and one Phase 2 and one Phase 1 candidate.  Its commercial product, ZTlido® (lidocaine topical system) 1.8%, or ZTlido®, is a prescription lidocaine topical product approved by the U.S. Food and Drug Administration for the relief of pain associated with postherpetic neuralgia, which is a form of post-shingles nerve pain.  Scilex in-licensed the exclusive right to commercialize Gloperba® (colchicine USP) oral solution, an FDA-approved prophylactic treatment for painful gout flares in adults, in the U.S. Scilex is planning to commercialize Gloperba® in 2023 and is well-positioned to market and distribute the product. Scilex’s three product candidates are SP-102 (injectable dexamethasone sodium phosphate viscous gel product containing 10 mg dexamethasone), or SEMDEXA™, a Phase 3, novel, viscous gel formulation of a widely used corticosteroid for epidural injections to treat lumbosacral radicular pain, or sciatica, with FDA Fast Track status; SP-103 (lidocaine topical system) 5.4%, a Phase 2, triple-strength formulation of ZTlido®, for the treatment of low back pain, with FDA Fast Track status; and SP-104, 4.5 mg Delayed Burst Release Low Dose Naltrexone Hydrochloride (DBR-LDN) Capsule, for the treatment of chronic pain, fibromyalgia that has completed multiple Phase 1 trial programs and expected to initiate Phase 2 trials this year. For further information regarding the SP-102 Phase 3 efficacy trial, see NCT identifier NCT03372161 – .

Scilex Holding Company is headquartered in Palo Alto, California, with operations in both Palo Alto and San Diego, California. For further information please visit .

About Sorrento Therapeutics, Inc.

Sorrento is a clinical and commercial stage biopharmaceutical company developing new therapies to treat cancer, pain (non-opioid treatments), autoimmune disease and COVID-19. Sorrento's multimodal, multipronged approach to fighting cancer is made possible by its extensive immuno-oncology platforms, including key assets such as Abivertinib, next-generation tyrosine kinase inhibitors (“TKIs”), fully human antibodies (“G-MAB™ library”), immuno-cellular therapies (“DAR-T™”), antibody-drug conjugates (“ADCs”), and oncolytic virus (“Seprehvec™”). Sorrento is also developing potential antiviral therapies and vaccines against coronaviruses, including STI-1558, COVI-MSC™; and diagnostic test solutions, including COVIMARK™.

Sorrento's commitment to life-enhancing therapies for patients is also demonstrated by our effort to advance a TRPV1 agonist, non-opioid pain management small molecule, resiniferatoxin (“RTX”), and SP-102 (10 mg, dexamethasone sodium phosphate viscous gel) (SEMDEXA™), a novel, viscous gel formulation of a widely used corticosteroid for epidural injections to treat lumbosacral radicular pain, or sciatica, and to commercialize ZTlido® (lidocaine topical system) 1.8% for the treatment of postherpetic neuralgia (PHN). RTX has been cleared for a Phase II trial for intractable pain associated with cancer and a Phase II trial in osteoarthritis patients. Positive final results from the Phase III Pivotal Trial C.L.E.A.R. Program for SEMDEXA™, its novel, non-opioid product for the treatment of lumbosacral radicular pain (sciatica), were announced in March 2022. ZTlido® was approved by the FDA on February 28, 2018.

For more information visit .

Contacts:

For Scilex Holding Company

Jaisim Shah

Chief Executive Officer

Scilex Holding Company

960 San Antonio Road

Palo Alto, CA 94303

Office: (650) 516-4310

Email: 

Website:   and 

Investors and Media Contact:

Elizabeth Czerepak

Email: 

Website:

Sorrento® and the Sorrento logo are registered trademarks of Sorrento Therapeutics, Inc.

G-MAB™, DAR-T™, Seprehvec™, SOFUSA™, COVI-MSC™, COVIMARK™, Ovydso™ and Fujovee™ are trademarks of Sorrento Therapeutics, Inc.

SEMDEXA™ (SP-102) is a trademark owned by Semnur Pharmaceuticals, Inc., a wholly-owned subsidiary of Scilex Holding Company.  A proprietary name review by the FDA is planned.

ZTlido® is a registered trademark owned by Scilex Pharmaceuticals Inc., a wholly-owned subsidiary of Scilex Holding Company.

Gloperba® is an exclusive, transferable license to use the trademark by Scilex Holding Company.

All other trademarks are the property of their respective owners. 

© 2023 Sorrento Therapeutics, Inc. All Rights Reserved.



EN
02/02/2023

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Reports on Sorrento Therapeutics Inc

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