New Research at ACC25 Shows Daxor BVA-Identified Euvolemic Heart Failure Patients Experience 2.61 Times Better Survival

Precise Volume Measurement Prior to Discharge Identifies Mortality Risk

Oak Ridge, TN, April 15, 2025 (GLOBE NEWSWIRE) -- (Nasdaq: DXR), the global leader in blood volume measurement technology, today announced compelling new data presented at the American College of Cardiology (ACC) 74th Annual Scientific Session and Expo held in Chicago from March 29-31st. Research from The Minneapolis Heart Institute Foundation^® and Allina Health Minneapolis Heart Institute^® demonstrated that hospitalized heart failure patients who received blood volume analysis (BVA) prior to hospital discharge could be used to stratify those with a substantially better survival rate.

The study, "Radiolabeled Blood Volume Analysis during Hospitalization for Acute Decompensated Heart Failure and 1-Year Mortality," presented by Hailey Miedema, research intern, Minneapolis Heart Institute Foundation, evaluated 1,237 hospitalized heart failure patients, including 202 who underwent BVA testing within two days of discharge.

Key findings:

• Patients confirmed as "euvolemic" (normal blood volume) through BVA showed markedly improved one-year survival rates
• In a Kaplan-Meier survival study, a hazard ratio, the risk of the event (in this case, death), is 2.61 times higher in the control group who were hypervolemic (congested) compared to the euvolemic group which BVA could uniquely identify
• This clinically significant hazard ratio quantifies survival differences across the entire follow-up period, accounting for both event occurrence and timing and had a very strong statistically significant p-value of 0.002
• The direct correlation between blood volume status and survival outcomes persisted even after adjusting for comorbidities
• Results strongly support the clinical value of objective blood volume measurement before discharging patients with acute decompensated heart failure to ensure successful treatment to euvolemia which only the BVA test was able to determine
  
  

Co- investigator Peter M. Eckman, MD, researcher at the Minneapolis Heart Institute Foundation and cardiologist and heart failure section head at the Allina Health Minneapolis Heart Institute, stated, "BVA is a great tool to ensure proper decongestion before discharge. This research indicates heart failure patients who achieve BVA-measured euvolemia experience higher one-year survival compared to those with hypervolemia."

"These findings represent a significant advancement in heart failure management and are consistent with numerous prior studies regarding the benefit of BVA in heart failure care" said John L. Jefferies, MD, MBA, MPH, Chief Medical Officer, Daxor Corporation. "By objectively measuring blood volume status before discharge, we can now identify patients at higher risk and optimize their treatment accordingly. This study validates what we've long believed—that precision volume management guided by BVA technology saves lives and improves outcomes for heart failure patients."

About Daxor Corporation

Daxor Corporation (Nasdaq: DXR), is the global leader in blood volume measurement technology focused on blood volume testing innovation. We developed and market the BVA-100^® (Blood Volume Analyzer), the only diagnostic blood test cleared by the FDA to provide safe, accurate, objective quantification of blood volume status and composition compared to patient-specific norms. Over 65,000+ tests have been performed at leading hospital centers across the U.S., enhancing hospital performance metrics in a broad range of surgical and medical conditions, including significantly reducing mortality and readmissions in heart failure and critical care. Daxor has several ongoing trials in the areas of heart failure treatment with support from the NIH and is under contract developing analyzers to improve combat casualty care with the U.S. Department of Defense. Daxor's mission is to advance healthcare by enabling optimal fluid management with blood volume analysis. Daxor’s vision is optimal blood volume for all. For more information, please visit our website at . Sign up to receive news on Daxor’s innovative technology .

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