Palisade Bio Enters into Strategic Collaboration with Strand Life Sciences to Advance Precision Medicine Approach

– Collaboration grants Palisade Bio access to cutting-edge expertise and tools in bioinformatics

– Partnership marks a significant value-driving milestone in Palisade Bio's mission to redefine UC treatment through targeted interventions based on PDE4-related biomarkers

Carlsbad, CA, April 23, 2024 (GLOBE NEWSWIRE) --  (Nasdaq: PALI) (“Palisade”, “Palisade Bio” or the “Company”), a biopharmaceutical company focused on developing and advancing novel therapeutics for patients living with autoimmune, inflammatory, and fibrotic diseases, today announced it has entered into a transformative strategic collaboration with Strand Life Sciences, a leading bioinformatics specialist, aimed at advancing precision medicine for ulcerative colitis (UC) therapy.

The collaboration with Strand Life Sciences provides Palisade Bio access to advanced bioinformatics tools vital for understanding complex disease pathways and predicting responses to PDE4 inhibitors. Leveraging data from over ten UC clinical studies, Palisade has curated a pipeline of 1600 UC patient samples, including transcriptomics and clinical outcomes. This curated dataset, analyzed using in-house tools, enables Palisade to identify biomarkers for selecting UC patient responders, utilizing machine learning to develop a precision medicine approach to patient selection.

"Our partnership with Strand Life Sciences signifies a pivotal advancement in our mission to revolutionize UC treatment," said Dr. Mitch Jones, CMO at Palisade Bio. "By harnessing the power of bioinformatics and leveraging extensive patient datasets, we are highly optimistic in our ability to deliver personalized therapies that offer new hope to patients living with UC. More immediately, the findings from this collaboration will provide valuable guidance and insight for our lead program, PALI-2108."

"We are thrilled to collaborate with Palisade Bio in this transformative endeavor toward advancing precision medicine for ulcerative colitis therapy," added Ramesh Hariharan, CEO at Strand Life Sciences. "Our expertise in bioinformatics, machine learning/AI and knowledge curation towards biomarker stratification, combined with Palisade's extensive patient datasets, holds immense promise in identifying predictive biomarkers and ultimately improving outcomes for UC patients."

Palisade Bio is committed to advancing precision medicine solutions for UC and other inflammatory indications. The Company is advancing its collaborative efforts with Strand Life Sciences and other partners to continue driving innovation and transforming the landscape of UC treatment.

About Palisade Bio 

Palisade Bio is a biopharmaceutical company focused on developing and advancing novel therapeutics for patients living with autoimmune, inflammatory, and fibrotic diseases. The Company believes that by using a targeted approach with its novel therapeutics it will transform the treatment landscape. For more information, please go to .

About Strand Life Sciences

Strand Life Sciences is a multiomics research and diagnostics company that combines a long track record in bioinformatics with cutting-edge, laboratory assays and a vast hospital partner network that enables omics-based biomarker discovery. Strand’s customers include global instrument, diagnostic and pharmaceutical companies. For more information, please go to .

Forward Looking Statements

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