HIGH POINT, N.C.--(BUSINESS WIRE)--
vTv Therapeutics Inc. (vTv) (Nasdaq: VTVT), a clinical-stage biopharmaceutical company engaged in the discovery and development of new orally administered treatments for Alzheimer’s disease, diabetes and other therapeutic areas, today announced that Company management will present two posters featuring vTv Therapeutics’ orally administered, non-peptide GLP-1R agonist at the American Diabetes Association’s 77th Scientific Sessions held in San Diego, California, June 9 – 13, 2017.
Details of the presentations are listed below:
Late-Breaking Poster title: “Is Less More? Learning to Dose the
Oral, Non-peptide GLP-1R Agonist, TTP273 in Type 2 Diabetics”
Poster
Number: 168-LB
Category: 12-E Clinical Therapeutics/New
Technology–Oral Agents
Date and Time: Sunday, June 11, 2017,
12 - 1:00pm PT
Location: Hall B
Poster title: “TTP273, Oral (Non-peptide) GLP-1R Agonist:
Improved Glycemic Control without Nausea and Vomiting in Phase 2”
Poster
number: 1220-P
Category: 12-E Clinical Therapeutics/New
Technology–Oral Agents
Date and Time: Sunday, June 11, 2017,
12 - 1:00pm PT
Location: Hall B
“We look forward to providing an update on TTP273, one of vTv’s lead diabetes compounds, at the American Diabetes Association’s 77th Scientific Sessions,” said Carmen Valcarce, Ph.D., executive vice president, chief scientific officer, vTv Therapeutics. “We remain focused on our goal of bringing forward both TTP273 and TTP399, vTv’s glucokinase activator, and continue to pursue opportunities with potential partners, including companies based outside the U.S. We are confident that we will find the right partner to support the continued development of these investigational therapies, which we believe could offer new options to patients with this disease.”
About TTP273
TTP273 is an investigational, orally dosed small molecule that works by activating the GLP-1 receptor. Activation of the GLP-1 receptor leads to the enhancement of insulin secretion and suppression of glucagon production and decreased food intake. There are currently several marketed injectable GLP-1 therapies. These agents have demonstrated notable glucose lowering in addition to weight loss; however, their widespread use may be hindered by the route of administration (injection) and by the high incidence of gastrointestinal side effects (nausea and vomiting).
About Type 2 Diabetes
Type 2 diabetes is a result of the body’s inability to use insulin properly to control sugar in the bloodstream. Type 2 diabetes represents up to 95% of diabetes patients, imposing a growing burden on healthcare systems globally. Diabetes remains the 7th leading cause of death in the United States, costing the healthcare system $245 billion annually. According to the American Diabetes Association, there are 29.1 million Americans, or 9.3% of the population, living with diabetes.
About vTv Therapeutics
vTv Therapeutics Inc. is a clinical-stage biopharmaceutical company engaged in the discovery and development of orally administered small molecule drug candidates to fill significant unmet medical needs. vTv has a pipeline of clinical drug candidates led by programs for the treatment of Alzheimer’s disease and Type 2 diabetes as well as treatment of inflammatory disorders and the prevention of muscle weakness.
Forward-Looking Statements
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