Update: Menarini deal highlights resminostat options
Menarini will develop 4SC’s resminostat in Asia Pacific in a deal worth up to €95m. With Yakult already a key partner in Japan (Phase II ongoing), resminostat can now be developed in a region that accounts for 75% of all liver cancer cases (HCC) globally. Although 4SC is committed to advancing resminostat for HCC, the deal could allow other development pathways to be pursued, subject to partner/finance being secured. We note recent developments in the HDAC field (eg Syndax-Merck deal for an HDAC/PD-1 combination) as proof of continuing interest from pharma companies.4SC is a biotechnology company that researches and develops drugs primarily for the treatment of cancer diseases. The Company has special expertise and clinical products in the field of epigenetics. 4SC's compounds aim to enable new therapeutic methods that offer improved efficacy and tolerability compared to the treatments available to date, both as monotherapy and in combination with other drugs. This approach is intended to enhance treatment benefits for affected patients, coupled with improvements to their life expectancy and quality of life. Adjusted for 1- for -5 stock split, April 2015Adjusted for 1- for -5 stock split, April 2015
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