Edison Investment Research - Achillion Pharmaceuticals Inc. (ACHN) Initiation: Potential all-oral HCV combination

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Edison Investment Research

Initiation: Potential all-oral HCV combination

Achillion is the only standalone biotech company with drug candidates in three key classes for HCV, hence it is in a prime position to develop its own, all-oral, once-a-day, interferon- and ribavirin-free, single pill HCV treatment that is as competitive as the leader in the space, Gileadâ€™s SOF/LDV fixed-dose coformulation (FDC). With promising efficacy in early stages of development shown, additional efficacy and safety data in more patients from later stage clinical trials will add value to the pipeline, leading to a possible corporate partnership deal. We value the company at $1,421m, or $14.5 per basic share.

29/09/2014 16 EN

Underlying

Achillion Pharmaceuticals Inc.

Achillion Pharmaceuticals is a biopharmaceutical company. The company is engaged in the discovery and development of small molecule drug therapies for immune system disorders. The company is advancing orally administered small molecules from its platform that target complement factor D, an essential protein of the alternative pathway. The alternative pathway plays a role in a number of disease conditions, including therapeutic areas of nephrology, hematology, ophthalmology and neurology. Initially Co. is targeting C3 glomerulopathy, and immune complex membranoproliferative glomerulonephritis, two related rare diseases affecting the kidney, and paroxysmal nocturnal hemoglobinuria, a blood disorder.

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US00448Q2012 United States

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Edison Investment Research

Edison is an investment research and advisory company, with offices in North America, Europe, the Middle East and AsiaPac. The heart of Edison is our world renowned equity research platform and deep multi-sector expertise. At Edison Investment Research, our research is widely read by international investors, advisors and stakeholders. Edison Advisors leverages our core research platform to provide differentiated services including investor relations and strategic consulting.

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