Update: Moving ahead with Factor-D in rare diseases
Thanks to its strong balance sheet following the out-licensing deal with Janssen in May 2015, Achillion appears to be well positioned to see its home-grown Factor-D program at least through the mid-stages of a clinical development program. Janssen’s equity purchase has helped to provide the financial muster needed for the company to invest in its early-stage small molecule therapeutics research platform, with its complement Factor D program at the forefront and on the verge of clinical testing.Achillion Pharmaceuticals is a biopharmaceutical company. The company is engaged in the discovery and development of small molecule drug therapies for immune system disorders. The company is advancing orally administered small molecules from its platform that target complement factor D, an essential protein of the alternative pathway. The alternative pathway plays a role in a number of disease conditions, including therapeutic areas of nephrology, hematology, ophthalmology and neurology. Initially Co. is targeting C3 glomerulopathy, and immune complex membranoproliferative glomerulonephritis, two related rare diseases affecting the kidney, and paroxysmal nocturnal hemoglobinuria, a blood disorder.
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