Report

AdAlta - Moving to an inhaled formulation

AdAlta has announced it will be moving forward with an inhaled formulation of AD-214 into efficacy studies in patients with idiopathic pulmonary fibrosis (IPF) rather than the original intravenous (IV) formulation. Preclinical studies with a radiolabelled version of AD-214 have indicated that IV dosing leads to much of the administered drug being rapidly distributed through the liver and cleared, rendering it unavailable to deliver a therapeutic effect. The company believes the advantages of an inhaled formulation will include a more direct form of administrations for lung diseases, potentially lower drug doses required for efficacy, and lower costs to manufacture and administer.
Underlying
AdAlta

Adalta develops its novel i-body platform with a focus on its candidate AD-114, a treatment for idiopathic pulmonary fibrosis (IPF) and other fibrotic diseases.

Provider
Edison Investment Research
Edison Investment Research

Edison is an investment research and advisory company, with offices in North America, Europe, the Middle East and AsiaPac. The heart of Edison is our world renowned equity research platform and deep multi-sector expertise. At Edison Investment Research, our research is widely read by international investors, advisors and stakeholders. Edison Advisors leverages our core research platform to provide differentiated services including investor relations and strategic consulting.

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Analysts
Sean Conroy

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