AdAlta - Preliminary Part A results
Part A of the AD-214 Phase I has been completed in 42 healthy volunteers who received a single dose of either AD-214 or placebo. There were no dose limiting or serious adverse events and no concerning clinical laboratory results. Additionally, AD-214 pharmacokinetics increased proportionally with the dose with evidence seen of CXCR4 engagement and high sustained receptor occupancy. AdAlta will now be investigating dosing every two weeks for AD-214 in the Part B portion of the study.Adalta develops its novel i-body platform with a focus on its candidate AD-114, a treatment for idiopathic pulmonary fibrosis (IPF) and other fibrotic diseases.
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