Antisense Therapeutics - Breaking the mould in DMD treatment
Antisense Therapeutics is an Australian biotechnology company developing antisense oligonucleotide (ASO) therapies for the treatment of rare diseases. Its lead asset, ATL1102, is being investigated as a targeted anti-inflammatory therapy to treat Duchenne muscular dystrophy (DMD). In a positive strategic pivot, trial design was amended to a smaller Phase IIb study (n=42 vs 108) that should provide a nearer-term catalyst, if positive readouts are achieved. As a result of the reduced trial costs, the company’s cash runway is anticipated to be extended (net cash at end-June 2022 of A$19.2m) into Q4 CY23. Management envisages a need to raise funds in the mid-single digit (A$m) region, which it anticipates will fund operations to trial readouts in Q124.Antisense Therapeutics is engaged in the research and development of its antisense products, which are under development. Co.'s antisense drugs are designed to bind to a specific messenger RNA sequence with precision and thereby block or stop the production of the disease causing protein in the first instance. Co. operates within the following segments: Multiple Sclerosis; and Growth and Sight Disorders.
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