Bionomics - Phase IIa in agitation of the elderly initiated
Bionomics announced on 23 May 2018 it has initiated a Phase IIa study of its α7 nicotinic receptor inhibitor for the treatment of agitation in the elderly in a hospital setting. Agitation is a common problem (13-24%) in patients with dementia, and we expect the trial to focus primarily on this population. It will enrol a target of 40 patients across Australia and is expected to provide top-line data in calendar Q119.Bionomics is a clinical stage biopharmaceutical company. Co utilizes its proprietary platform technologies to discover and develop a pipeline, drug candidates focused on the treatment of central nervous system disorders and on the treatment of cancer. Co.'s key drug candidate BNC210, which for the treatment of generalized anxiety disorder, is a proprietary negative allosteric modulator of the alpha-7 nicotinic acetylcholine receptor. Co. also develops BNC101, which its lead humanized monoclonal antibody targeting a key receptor on cancer stem cells that is overexpressed in metastatic colorectal cancer, metastatic pancreatic cancer and many other solid tumors.
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