Edison Investment Research - Immunicum AB (IMMU) Mendus - Stars align for CADENCE combination trial

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Edison Investment Research

Sean Conroy

Mendus - Stars align for CADENCE combination trial

Mendus is forging ahead with vididencel, its primary clinical asset, aiming to address a market niche: the acute myeloid leukaemia (AML) maintenance setting. The company is gearing up to launch the Phase II CADENCE combination trial assessing its lead cancer vaccine candidate, vididencel, in combination with oral azacitidine (Onureg), the only approved AML maintenance drug, to prevent relapse after remission for AML patients. This study is being conducted in collaboration with the Australasian Leukaemia and Lymphoma Group, leveraging Mendus’s local expertise and clinical trial network. During a recent business update, management indicated that the company has received positive feedback from the FDA regarding late-stage development. Mendus expects to commence a global registrational trial in H225, with manufacturing to be guided through the alliance with NorthX Biologics and large-scale Good Manufacturing Practice (GMP) batches expected from mid-2025. The CADENCE trial is on track to start recruiting patients in April 2024.

13/03/2024 1 EN

Underlying

Immunicum AB

Immunicum AB is a Sweden-based company principally engaged in the biopharmaceutical sector. The Company develops immunotherapy for therapeutic treatment of cancer and infectious diseases. The Company uses therapeutic vaccines to treat an already existing disease and is thus given to the already sick patients; therapeutic cancer vaccines administered to patients in order to delay or stop tumor cell growth, shrink tumors, prevent relapse, or to kill cancer cells that could not be eliminated with other treatments. The Company has several technology platforms, such as The Combig, Intuvax@, Subcuvax@ and The CD70, among others. The Company has several projects which are related to kidney cancer and liver cancer, among others.

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SE0005003654 Nasdaq Nordic Stockholm Sweden

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Edison Investment Research

Edison is an investment research and advisory company, with offices in North America, Europe, the Middle East and AsiaPac. The heart of Edison is our world renowned equity research platform and deep multi-sector expertise. At Edison Investment Research, our research is widely read by international investors, advisors and stakeholders. Edison Advisors leverages our core research platform to provide differentiated services including investor relations and strategic consulting.

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Analysts

Sean Conroy

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Mendus - Stars align for CADENCE combination trial

Mendus - Gross proceeds of c SEK69m to advance pipeline

Mendus - Regulatory green light for CADENCE trial

Mendus to present NK cell program progress at the Innate Killer Summit

Basilea Pharmaceutica - Cresemba milestone payments continue to roll in

AAC Clyde Space - Solid start to the year with further order growth

Tinexta - Typical seasonality in Q124

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