Edison Investment Research - INTEC PHARMA (NTEC) Intec Pharma - Phase III more than half the way there

Report

Edison Investment Research

Maxim Jacobs

Intec Pharma - Phase III more than half the way there

The year 2017 was marked by steady progress in Intecâ€™s development program of AP-CDLD for the treatment of Parkinsonâ€™s disease (PD). The drug is a co-formulation of widely used carbidopa and levodopa using the companyâ€™s proprietary accordion pill (AP) technology. The program is in Phase III with more than 300 (of 420) patients enrolled to date with full enrolment expected in H218.

22/03/2018 6 EN

Underlying

INTEC PHARMA

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Provider

Edison Investment Research

Edison is an investment research and advisory company, with offices in North America, Europe, the Middle East and AsiaPac. The heart of Edison is our world renowned equity research platform and deep multi-sector expertise. At Edison Investment Research, our research is widely read by international investors, advisors and stakeholders. Edison Advisors leverages our core research platform to provide differentiated services including investor relations and strategic consulting.

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Analysts

Maxim Jacobs

Other Reports on these Companies

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Intec Pharma - Continued confidence in AP-CDLD

Intec Pharma has developed a unique drug delivery platform, the accordion pill (AP) and is enrolling a 420-patient trial of AP-CDLD for Parkinsonâ€™s disease (PD), with full enrolment expected in Q318. Many of the adverse effects associated with the treatment of PD with levodopa (the standard of care), such as off-time and troublesome dyskinesia, are directly associated with its pharmacokinetic (PK) profile. Recently released data from two PK studies of AP-CDLD showed their formulation had lower peak serum concentrations and a longer half-life, which should lower these side effects.

July 23, 2018 July 23, 2018 6 EN

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Intec Pharma - Bolstering the case for AP-CDLD

Intec Pharma recently released the results from two pharmacokinetic (PK) studies of AP-CDLD (n=18 and n=30). The data showed trends towards lower peak serum concentrations (Cmax) and a longer half-life (T1/2, although there was some inconsistency), which should reduce dyskinesia and off-time, respectively. Additionally, one study measured food effect, which was present but did not delay onset of effects, unlike the approved extended-release carbidopa/levodopa formulation, Rytary.

May 21, 2018 May 21, 2018 6 EN

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Intec Pharma - Phase III more than half the way there

Intec Pharma - Continued confidence in AP-CDLD

Intec Pharma - Bolstering the case for AP-CDLD

Manx Financial Group - Termination of coverage

musicMagpie - Termination of coverage

Topps Tiles - Accelerating growth through Q125

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