Edison Investment Research - Midatech Pharma (MTPH) Midatech Pharma - Development pipeline expands with MTD217

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Edison Investment Research

Sean Conroy

Midatech Pharma - Development pipeline expands with MTD217

Midatech has announced a new preclinical programme, MTD217, targeting leptomeningeal disease, a secondary metastatic cancer of the central nervous system (CNS), with currently poor prognosis (average survival of 3–6 months). The drug will be developed using the MidaSolve platform (dissolves otherwise insoluble drugs that can then be injected directly to the site of the cancer to maximise efficacy and reduce off-target toxicity). Midatech is working on initiating preclinical studies (in collaboration with several large academic centres) with the aim to generate proof-of-concept data to support clinical progression. We highlight that in the recently concluded AGM, Midatech shareholders approved all key resolutions, including 1:20 share consolidation, change of trading name to Biodexa Pharmaceuticals and stock delisting from AIM. Midatech raised £5m in gross proceeds through a private placement, which we expect will be partially used to accelerate preclinical studies for MTD217. Lead asset MTX110 is in Phase I clinical studies in recurrent glioblastoma.

28/03/2023 1 EN

Underlying

Midatech Pharma

Midatech Pharma is a holding company. Through its subsidiaries, Co. is engaged as a specialty pharmaceutical company focused on the development and commercialization of multiple therapeutic products, using its nanomedicine and sustained release technologies, to enhance the delivery of medicines in major diseases with high unmet medical needs. These diseases include diabetes, certain cancers such as liver, ovarian and brain (glioblastoma) and neurological/ophthalmologic conditions. Co.'s two platform technologies are designed to enable targeted delivery and sustained release of existing therapeutic drugs to the "right place" at the "right time."

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GB00BKT14T00 London Stock Exchange United Kingdom

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Edison Investment Research

Edison is an investment research and advisory company, with offices in North America, Europe, the Middle East and AsiaPac. The heart of Edison is our world renowned equity research platform and deep multi-sector expertise. At Edison Investment Research, our research is widely read by international investors, advisors and stakeholders. Edison Advisors leverages our core research platform to provide differentiated services including investor relations and strategic consulting.

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Analysts

Sean Conroy

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Midatech Pharma - Development pipeline expands with MTD217

Biodexa Pharmaceuticals - Pivoting out of a challenging FY22

Hybridan Small Cap Feast 08/03/22

Basilea Pharmaceutica - Cresemba milestone payments continue to roll in

AAC Clyde Space - Solid start to the year with further order growth

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