Edison Investment Research - Mologen AG (MGN) Outlook: Pivotal cancer immunotherapy player

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Edison Investment Research

Outlook: Pivotal cancer immunotherapy player

Mologen is developing cancer immunotherapies for the post-chemo maintenance setting, a unique position within this burgeoning field. Lead candidate MGN1703 (TLR9 agonist) is poised to enter a pivotal Phase III study (IMPALA) in Q314, as a maintenance therapy after first-line chemotherapy in patients with metastatic colorectal cancer (mCRC). A Phase II trial (IMPULSE) in small-cell lung cancer (SCLC) is also underway, and results in Q415 could rekindle partnership discussions; fresh finance will be required in 2015/16. We value Mologen at â‚¬340m, or â‚¬20 per share.

15/07/2014 12 EN

Underlying

Mologen AG

Mologen is a biotechnology company researching and developing deoxyribonucleic acid (DNA)-based drugs for diseases that require a high degree of medical treatment. Co.'s activities concentrate on creating new and improving existing immunological drugs and therapies to combat cancer and developing vaccines for the prevention and treatment of serious infectious diseases in humans, as well as animals. Two core areas of Co.'s operations are the treatment of cancer and infectious diseases. Co. developed and patented two technologies that allow for the use of DNA as a therapeutic treatment against diseases that were previously incurable or treatable to an unsatisfactory degree.

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DE0006637200 Germany

Provider

Edison Investment Research

Edison is an investment research and advisory company, with offices in North America, Europe, the Middle East and AsiaPac. The heart of Edison is our world renowned equity research platform and deep multi-sector expertise. At Edison Investment Research, our research is widely read by international investors, advisors and stakeholders. Edison Advisors leverages our core research platform to provide differentiated services including investor relations and strategic consulting.

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Outlook: Pivotal cancer immunotherapy player

MOLOGEN - IMPALA readout ends monotherapy strategy

MOLOGEN - IMPALA readout ends monotherapy strategy

Mologen - Retaining lefitolimod's value

IP Group - Several potential portfolio catalysts on the horizon

Actinogen Medical - First patient dosed in Phase IIb XanaMIA study

Cereno Scientific - CS014 (thrombosis) progresses towards the clinic

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