Newron Pharmaceuticals - Evanamide potential expanding in schizophrenia
Newron Phamaceuticals has announced encouraging interim safety and efficacy data for the use of evanamide, a glutamate modulator, as an add-on therapy in treatment-resistant schizophrenia (TRS). Data from the first 100 patients who completed the six-week open-label study 014 (assessing the drug candidate as an add-on in moderate-to-severe TRS) found it improved symptoms of psychosis. A high proportion (77%) of all treated patients responded to their antipsychotic (AP) therapy after the addition of evanamide (dosed at 7.5mg, 15mg or 30mg twice daily). The drug was well tolerated in combination with all APs tested. We see these data as further support for the glutamate hypothesis of schizophrenia and, by extension, management’s approach to treating the disease. Considering this news, we are reviewing our estimates.Newron Pharmaceuticals is a clinical stage biopharmaceutical company. Co. is focused on the development of drugs for the treatment of central nervous system disorders and pain. Co.'s pipeline include, Xadago® (safinamide), for the treatment of Parkinson's disease (PD) and PD Levodopa-induced dyskinesia; Sarizotan, for the treatment of Rett syndrome (Orphan drug status); Evenamide (NW-3509), for the treatment of Schizophrenia and Clozapine-treatment-resistant schizophrenia; and Ralfinamide for patients with specific rare pain indications (neuropathic pain).
Edison is an investment research and advisory company, with offices in North America, Europe, the Middle East and AsiaPac. The heart of Edison is our world renowned equity research platform and deep multi-sector expertise. At Edison Investment Research, our research is widely read by international investors, advisors and stakeholders. Edison Advisors leverages our core research platform to provide differentiated services including investor relations and strategic consulting.
.
Unfortunately, this report is not available for the investor type or country you selected.
Browse all ResearchPool reportsReport is subscription only.
Thank you, your report is ready.
Thank you, your report is ready.