Edison Investment Research - ReNeuron Group (RENE) ReNeuron Group - Extension trial back on track but with data delay

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Edison Investment Research

Sean Conroy

ReNeuron Group - Extension trial back on track but with data delay

The key news in the FY21 results statement was the restart of the Phase IIa (2m cell dose) extension study after a June safety halt due to a presumed intraocular eye infection (endophthalmitis). If some trial data is available by Q4 of CY21, this could open the way to a crucial partnering deal from probably mid-2022. The 12-month data from the first (1m dose) Phase IIa cohort showed stable responses with the two best patients seeing a doubling of their visual acuity. Preclinical projects in exosomes (drug targeting and delivery) and candidate cell lines (like a diabetes therapy) are progressing well but with no major partnerships as yet. FY21 (year ending 31 March) closed with £22.2m cash. Our valuation remains at £190m.

15/07/2021 9 EN

Underlying

ReNeuron Group

Reneuron Group researches and develops therapies using stem cells. Co.'s products include: CTX cells for stroke disability, which is its therapeutic candidate for the treatment of patients left disabled by the effects of a stroke; human retinal progenitor cells (hRPCs) for retinitis pigmentosa (RP), which is its therapeutic hRPC candidate for the treatment of RP, a blindness-causing disease of the retina; hRPCs for cone-rod dystrophy, which is a hRPC therapeutic candidate across a range of genetic diseases of the eye; and CTX-derived exosomes, which is its exosomes nanomedicine platform that generates early pre-clinical data in cancer.

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GB00BF5G6K95 London Stock Exchange United Kingdom

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Edison Investment Research

Edison is an investment research and advisory company, with offices in North America, Europe, the Middle East and AsiaPac. The heart of Edison is our world renowned equity research platform and deep multi-sector expertise. At Edison Investment Research, our research is widely read by international investors, advisors and stakeholders. Edison Advisors leverages our core research platform to provide differentiated services including investor relations and strategic consulting.

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Analysts

Sean Conroy

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ReNeuron Group - Extension trial back on track but with data delay

Hardman & Co Insight: Survival of the UK life sciences sector

ReNeuron Group - Termination of coverage

Hardman & Co Healthcare Index: 2023 – Capital demands dent performance

Manx Financial Group - Termination of coverage

musicMagpie - Termination of coverage

Topps Tiles - Accelerating growth through Q125

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