Report

Ultimovacs - Peer-reviewed publication reiterates UV1’s potential

Ultimovacs’ results from the Phase II NIPU trial for its universal, off-the-shelf cancer vaccine UV1 in second-line metastatic pleural mesothelioma (MPM) have been published in the European Journal of Cancer, a well-regarded peer-reviewed journal. NIPU is one of the company’s five Phase II programmes for UV1, used in combination with immune checkpoint inhibitors (ICIs). The publication highlighted the growing utility of the combination approach and reiterated the promising efficacy of UV1 with the ICIs ipilimumab and nivolumab (IPI-NIVO), which improved overall survival of patients (27% reduction in risk of death versus IPI-NIVO alone). We await further clarity on the upcoming Phase III trial, but expect clinical activity to commence within 2024. This month will be important for the company as anticipation builds toward the upcoming results from the Phase II INITIUM trial in malignant melanoma.
Underlying
Ultimovacs

Ultimovacs ASA Formerly known as Ultimovacs AS. Ultimovacs ASA, formerly Ultimovacs AS, is a Norway-based pharmaceutical company developing immunotherapies against cancer. The Company's lead product candidate is UV1, a peptide-based vaccine inducing a specific T cell response against the universal cancer antigen telomerase. UV1 is being developed as a therapeutic cancer vaccine which may serve as a platform for use in combination with other immuno-oncology drugs which require an ongoing T cell response for their mode of action. The Company is performing a broad clinical development program with clinical trials in Europe and the USA.

Provider
Edison Investment Research
Edison Investment Research

Edison is an investment research and advisory company, with offices in North America, Europe, the Middle East and AsiaPac. The heart of Edison is our world renowned equity research platform and deep multi-sector expertise. At Edison Investment Research, our research is widely read by international investors, advisors and stakeholders. Edison Advisors leverages our core research platform to provide differentiated services including investor relations and strategic consulting.

.

Analysts
Sean Conroy

Other Reports on these Companies
Other Reports from Edison Investment Research

ResearchPool Subscriptions

Get the most out of your insights

Get in touch