London, UK, 13 July 2021

Xintela (XINT): Initiation - Advancing integrins as innovation engine

Xintela, backed by its integrin biomarker technology platform XINMARK, is a potential disrupter in the regenerative stem cell and oncology areas. Initial targets are osteoarthritis (OA), glioblastoma (GBM) and triple negative breast cancer (TNBC), all areas with significant unmet need. 2021 could be a transformational year with an expected start for a Phase I/IIa trial for OA and the planned spinoff of the oncology arm. ARDS optionality in the COVID-19 world presents an outside opportunity too. Potential deals or partnerships in animal OA and oncology are near-term triggers.

With preclinical trials complete and the crucial GMP certification achieved (May 2021), timely commencement of the clinical Phase I/IIa knee OA study and successful conclusion of the planned Targinta spin-off (potentially unlocking untapped value) should be the next catalysts for Xintela. Concerns around funding needs have been alleviated to a degree by the SEK28m directed share issue in June 2021, with the company seeking to secure various forms of long-term financing for both Xintela and Targinta.

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