180 Degree Capital is a closed-end management investment company. The company operates as an internally managed investment company. The company invests in both short- and long-term United States government and agency securities. To the extent that the company invests in short- and long-term United States government and agency securities, changes in interest rates result in changes in the value of these obligations that result in an increase or decrease of its net asset value. The company is focused on investing in undervalued microcapitalization publicly traded companies.
Aldeyra Therapeutics is a biotechnology company engaged in developing and commercializing medicines for patients with immune-mediated diseases. The company's primary product candidate, reproxalap, is a treatment in late-stage development for dry eye disease and allergic conjunctivitis. The company has additional product candidates in development for proliferative vitreoretinopathy and other retinal diseases, autoimmune disease, and cancer. The company has discovered and are developing two additional reactive aldehyde species inhibitors, ADX-103 and ADX-629, for the treatment of retinal disease and autoimmune disease, respectively.
Arcturus Therapeutics is an emerging biopharmaceutical company primarily focused on the development and commercialization of a proprietary oral drug candidate, MDX, to treat ADHD and other cognitive dysfunctions including Fragile X Syndrome. The most common available treatments for ADHD are stimulants that increase the brain chemicals dopamine and norepinephrine. Stimulants have significant side effects, and are classified as controlled substances which have significant potential for misuse, abuse and addiction. MDX is not a stimulant, and works with a different mechanism of action. MDX is a proprietary, combined rapid onset release formulation of the chemical Pyridoxine Pyroglutamate.
Argan is a holding company. The company conducts operations through its subsidiaries: Gemma Power Systems, LLC, which is an engineering, procurement and construction contractor; Atlantic Projects Company Limited, which provides turbine, boiler and rotating equipment installation, commissioning and outage services; The Roberts Company, Inc., which provides on-site services that support maintenance, shutdowns and emergency mobilizations for industrial plants in the southern region of the U.S.; and Southern Maryland Cable, Inc., which conducts business as SMC Infrastructure Solutions, and provides technology wiring and utility construction solutions to customers in the mid-Atlantic region of the U.S.
Athenex is a biopharmaceutical company focused on the discovery, development and commercialization of drugs for the treatment of cancer. The company has three platforms: its Oncology Innovation Platform, dedicated to the research and development of its proprietary drugs; its Commercial Platform, focused on the sales and marketing of its specialty drugs and the market development of its proprietary drugs; and its Global Supply Chain Platform, dedicated to providing a supply of active pharmaceutical ingredients for its clinical and commercial efforts. The company's clinical pipeline includes: Orascovery, Src Kinase inhibition, T-cell Receptor-engineered T-cells, and arginine deprivation therapy.
Beyond Air is a medical device company developing a nitric oxide (NO) generator and delivery system (the Beyond Air NOGDS) that is capable of generating NO from ambient air. The Beyond Air NOGDS can deliver NO either continuously or for a fixed amount of time at various flow rates and has the ability to either titrate dose on demand or maintain a constant dose. The company's initial areas of focus are persistent pulmonary hypertension of the newborn (PPHN), bronchiolitis and nontuberculous mycobacteria. With respect to PPHN, the company's Beyond Air NOGDS is designed to deliver a dosage of low-concentration of NO to the lungs. The company's Beyond Air NOGDS can also deliver a high concentration of NO to the lungs.
Brainstorm Cell Therapeutics is a biotechnology company engaged in the development and commercialization of autologous cellular therapies for the treatment of neurodegenerative diseases including: Amyotrophic Lateral Sclerosis; Progressive Multiple Sclerosis; and Parkinson's disease. NurOwn? technology is based on manufacturing protocol, which induces the differentiation of purified and expanded bone marrow-derived mesenchymal stem cells and consistently generates cells that release multiple neurotrophic factors to modulate neuroinflammatory and neurodegenerative disease processes, promote neuronal survival and improve neurological function.
CASI Pharmaceuticals is a biopharmaceutical company focused on developing and commercializing therapeutics and pharmaceutical products. The company's primary product and candidates in hematology/oncology include: EVOMELA (Melphalan for Injection), an intravenous formulation of melphalan commercialized in the multiple myeloma treatment setting in the United States; CNCT19, which targets CD19, a B-cell surface protein expressed during all phases of B-cell development and a validated target for B-cell driven hematological malignancies; CID-103, an investigational anti-CD38 monoclonal antibody being developed for the treatment of patients with multiple myeloma.
Cassava Sciences is a clinical-stage drug development company. The company focuses on developing new product candidates and to guide these through various regulatory and development pathways in preparation for their potential commercialization. The company's clinical-stage biopharmaceutical assets include: PTI-125, which is its product candidate for the treatment of Alzheimer's disease; and PTI-125Dx, which it is developing as a blood-based biomarker/diagnostic to detect Alzheimer's disease. The company owns worldwide rights to PTI-125 and PTI-125Dx, without royalty obligations to any third party.
ChemoCentryx is a biopharmaceutical company developing medications targeted at inflammatory disorders, autoimmune diseases and cancer. Each of the company's drug candidates is designed to selectively block a specific chemoattractant receptor. The company's drug candidates are small molecules, which are orally administered. The company's product development portfolio features drug candidates in therapeutic areas of immunology, oncology and immuno-oncology. The company's primary drug candidate is avacopan, an orally-administered molecule that employs a targeted mode of action in the treatment of anti-neutrophil cytoplasmic antibody-associated vasculitis and other complement-driven autoimmune and inflammatory diseases.
ClearOne designs, develops and sells conferencing, collaboration and network streaming solutions for voice and visual communications. The company's line of conferencing and collaboration products are targeted for large, medium and small businesses, as well as for personal use. The company's products can be categorized into the following: audio conferencing including installed DSP based professional audio conferencing, USB-based speakerphones and table-top audio conferencing; microphones consisting of patented beamforming microphones, ceiling microphones and wireless microphones; and video products including video collaboration and AV networking.
Clipper Realty is a self-administered and self-managed real estate company that acquires, owns, manages, operates and repositions multifamily residential and commercial properties in the New York metropolitan area, with a portfolio in Manhattan and Brooklyn.
Corporate Office Properties Trust is a real estate investment trust. Corporate Office Properties, L.P. (COPLP) and subsidiaries is the entity through which the company, the sole general partner of COPLP, conducts almost all of its operations and owns almost all of its assets. The company owns, manages, leases, develops and selectively acquires office and data center properties. The majority of the company's portfolio is in locations that support the United States Government and its contractors that engaged in national security, defense and information technology related activities servicing. The company also owns office properties in select urban/urban-like submarkets in the Greater Washington, DC/Baltimore region.
CubicFarm Systems Corp is a Canada-based agriculture technology and vertical farming company. The Company develops and employs technology to provide predictable crop yields. The Company installs turnkey commercial scale, hydroponic, automated vertical farm growing solutions. It also provides a seed to store shelf solution including design, installation, training, packaging, marketing and branding support. Its system addresses the two challenges in the vertical farming industry, high electricity and labor costs, using undulating path technology. The Company leverages its technology by operating its own facility in Pitt Meadows, British Columbia.
Evolent Health is a holding company. Through its subsidiaries, the company is a managed care services firm that supports health systems and physician organizations in their migration toward care and population health management. The company's Services segment provides its customers, who it refers to as partners, with a population health management platform, integrated data and analytics capabilities, claims processing services, including pharmacy benefit management, specialty care management services and health plan administration services. The company's subsidiary, True Health New Mexico, Inc. is a physician-led health plan in New Mexico available via the commercial market for employer-sponsored health coverage.
FleetCor Technologies is provider of commercial payment solutions. The company's five primary product lines are Fuel, which provides fuel payment solutions to businesses and government entities who operate vehicle fleets, as well as to main oil companies;Lodging, which provides lodging payment solutions to employees who travel overnight for work purposes; Tolls, which provides an electronic toll and parking payments product; Corporate Payments, which include virtual cards, purchasing cards, travel and entertainment cards; and Gift, which provides gift card product management and processing services. Additionally, the company provides other payment products including fleet maintenance and employee benefits.
Fluent provides digital marketing services. The company primarily performs customer acquisition services by operating digital marketing campaigns, through which the company connects its advertiser clients with consumers. The company delivers data and performance-based marketing executions to its clients, across a range of industries, including Financial Services, Retail and Consumer, Media and Entertainment, Staffing and Recruitment and Marketing Services. The company provides performance marketing solutions to its clients based on their desired outcomes, or specific actions in their marketing funnels, including submission of a registration form, app installation or a completed transaction.
Frequency Electronics is engaged in precision time and frequency generation technology. The company's segments are: FEI-NY and FEI-Zyfer. The FEI-NY segment includes the operations of the company's wholly-owned subsidiaries, FEI-Asia and FEI-Elcom. FEI-Asia functions as a manufacturing facility for FEI-NY and FEI-Zyfer. FEI-Elcom provides design and technical support for the FEI-NY segment's business. The FEI-Zyfer segment designs and manufactures products which incorporate global positioning systems technologies and clocks designed and manufactured at FEI-NY. FEI-Zyfer sells its products to both commercial and U.S. Government customers and collaborates with FEI-NY on joint product development activities.
Globalstar provides mobile satellite services including voice and data communications services via satellite. The company provides the following communications services via satellite: two-way voice communication and data transmissions using mobile or fixed devices including its GSP-1700 phone; one-way or two-way communication and data transmissions using mobile devices, including its SPOT family of products such as SPOT X?, SPOT Gen3 and Trace; and one-way data transmissions using a mobile or fixed device that transmits its location and other information to a central monitoring station, including its commercial Simplex products, such as its battery and solar-powered SmartOne, STX-3 and STINGR.
Jernigan Capital is a commercial real estate company that invests primarily in new or recently-constructed and opened self-storage facilities located in dense urban submarkets within U.S. metropolitan statistical areas (MSAs). The company conducts its investment activities through its operating company, Jernigan Capital Operating Company, LLC. The company focuses on originating the following types of investments: Development Property Investments, which finances ground-up construction of self-storage facilities or self-storage conversion or redevelopment opportunities within the MSA; Wholly-Owned Property Investments; and Bridge Investments.
Kingstone Companies is an insurance holding company. Through its wholly-owned subsidiary, Kingstone Insurance Company (KICO), the company provides property and casualty insurance products to individuals and small businesses. KICO is a licensed property and casualty insurance company in New York, New Jersey, Connecticut, Massachusetts, Pennsylvania, Rhode Island, Maine and New Hampshire. The company's product lines include: personal lines, which provide homeowners and dwelling fire multi-peril, cooperative/condominiums and personal umbrella policies; commercial liability, which provides businessowners policies; and livery physical damage, which writes for-hire vehicle physical damage only policies.
KLX Energy Services is a holding company. Through its subsidiaries, the company is a provider of completion, intervention and production services and products to the major onshore oil and gas producing regions of the United States. The company offers a range of differentiated, complementary technical services and related tools and equipment in challenging environments that provide "mission critical" solutions for the company's customers throughout the life cycle of the well.
Limbach Holdings is a commercial specialty contractor in the areas of heating, ventilation, air-conditioning (HVAC), plumbing, electrical and building controls for the design and construction of new and renovated buildings, maintenance services, energy retrofits and equipment upgrades. The company provides facility services consisting of mechanical construction, HVAC service and maintenance, energy audits and retrofits, among others. The company operates in two segments: Construction, in which the company manages construction or renovation projects that involve primarily HVAC, plumbing or electrical services; and Service, in which the company provides maintenance or service on HVAC, plumbing or electrical systems.
Matador Resources is an independent energy company engaged in the exploration, development, production and acquisition of oil and natural gas resources in the United States, with a focus on oil and natural gas shale and other unconventional plays. The company's operations are focused on the oil and liquids-rich portion of the Wolfcamp and Bone Spring plays in the Delaware Basin in Southeast New Mexico and West Texas. The company also operates in the Eagle Ford shale play in South Texas and the Haynesville shale and Cotton Valley plays in Northwest Louisiana. Also, the company conducts midstream operations, through its midstream joint venture, San Mateo Midstream, LLC together with San Mateo Midstream II, LLC.
MEI Pharma is a late-stage pharmaceutical company focused on development and oncology capabilities to identify and develop therapies for the treatment of cancer. The company has four clinical-stage development programs with approaches to inhibiting cancer, including epigenetics, cell signalling and cancer metabolism: ME-401, an oral phosphatidylinositol 3-kinase delta inhibitor; Voruciclib, an oral cyclin-dependent kinase inhibitor; ME-344, a mitochondrial inhibitor targeting the oxidative phosphorylation complex; and Pracinostat, an oral histone deacetylase inhibitor being evaluated in a pivotal Phase 3 global registration clinical trial for the treatment of adults with acute myeloid leukemia.
MTS Systems supplies test, simulation and measurement systems and sensors. The company's Test and Simulation segment provides testing solutions including hardware, software and services. Products, service and customers are grouped into three global sectors: ground vehicles, materials, and structures. The company's Sensors segment is engaged in sensing technologies and solutions used by design engineers and predictive maintenance personnel. Sensors products and solutions serve the automotive, aerospace, industrial, defense, and research and development markets. Sensors products and customers are grouped into four global sectors: positional sensors, test sensors, industrial sensors, and systems sensors.
Ocugen is focused on its product, NeoCart?, a cell therapy that utilizes various aspects of the company's restorative cell therapy platform to treat tissue injury in the field of orthopedics, specifically cartilage damage in the knee. The company's NeoCart Phase 3 clinical trial is designed, randomized clinical trial in North America evaluating the safety and efficacy of a restorative cell therapy to treat knee cartilage damage. The company has a License and Commercialization Agreement with MEDINET Co., Ltd. with regards to the commercialization of NeoCart in Japan. HISTOGENICS (and design), its logo design and NEOCART are the company's registered trademarks.
Opko Health is a healthcare company. The company manages two segments: Diagnostics, which provides laboratory testing services utilized by healthcare providers in the detection, diagnosis, evaluation, monitoring, and treatment of diseases, including esoteric testing, molecular diagnostics, anatomical pathology, genetics, women's health and correctional healthcare; and Pharmaceutical, which includes Rayaldee for the treatment of secondary hyperparathyroidism in adults with chronic kidney disease (CKD) and vitamin D insufficiency, and Alpharen (Fermagate Tablets) for the treatment of hyperphosphatemia in CKD patients requiring regular hemodialysis.
PacWest Bancorp is a bank holding company. Through its subsidiary, Pacific Western Bank, the company is focused on relationship-based business banking to small, middle-market, and venture-backed businesses nationwide. The company's Community Banking group provides real estate loans, commercial loans, and deposit and treasury management services to small and medium-sized businesses. The company's National Lending group provides asset-based, equipment, and real estate loans and treasury management services to middle-market businesses. The company's Venture Banking group provides loans and financial services focused on entrepreneurial and venture-backed businesses and their venture capital and private equity investors.
Protagonist Therapeutics is a clinical-stage biopharmaceutical company with a proprietary technology platform that discovers and develops peptide-based drug candidates. The company's product candidates include: PTG-300, which is an injectable hepcidin mimetic for the treatment of patients with beta-thalassemia; PTF-200, which is an oral gastrointestinal (GI)-restricted Interleukin-23 receptor antagonist peptide product candidate for the treatment of inflammatory bowel disease (IBD); and PN-943, which is an oral, alpha-4-beta-7 antagonist for the treatment of IBD. The company is researching oral and injectable peptide-based product candidates for a range of conditions including hematology and GI diseases.
Red Robin Gourmet Burgers, together with its subsidiaries, primarily develops, operates, and franchises restaurants in North America and focuses on serving gourmet burgers. The company's menu features its product, a line of Gourmet Burgers. To complement its Gourmet Burgers Co. provides a line of Red's Tavern Double? burgers. In addition to burgers, the company serves an array of other items. These items include a variety of appetizers, salads, soups, seafood, and other entrees. The company also provides a range of single-serving and shareable desserts as well as its Finest milkshakes. The company's beverages include alcoholic and non-alcoholic specialty drinks, cocktails, wine, and a variety of national and craft beers.
RiceBran Technologies is an ingredient company serving food, animal nutrition and specialty markets focused on processing and marketing of healthy, natural and nutrient dense products derived from raw rice bran, an underutilized by-product of the rice milling industry. The company converts raw rice bran into various products including: stabilized rice bran (SRB); RiBalance, a rice bran nutritional package derived from further processing of SRB; RiSolubles, a nutritious, carbohydrate and lipid rich fraction of RiBalance; RiFiber, a protein and fiber rich insoluble derivative of RiBalance; and its family of ProRyza products, which includes derivatives composed of protein and protein/fiber blends.
Sage Therapeutics is a clinical-stage biopharmaceutical company focused on developing and commercializing medicines to treat life-altering central nervous system disorders. The company's principal product candidate is ZULRESSO? (brexanolone) injection, a proprietary intravenous formulation of brexanolone for the treatment of postpartum depression (PPD). The company's other product candidate is SAGE-217, an oral compound that is being developed for PPD and major depressive disorder. The company also has a portfolio of other compounds that target GABAA receptors, which include SAGE-324 and SAGE-689. The company's second area of focus is the development of compounds that target the NMDA receptor, which include SAGE-718.
Schmitt Industries is engaged in providing precision test, measurement and process control products. The company has the following segments: Balancer, which designs, manufactures and sells computer-controlled vibration detection, balancing and process control systems for the worldwide machine tool industry, particularly for grinding machines; and Measurement, which through its wholly owned subsidiary, Schmitt Measurement Systems, Inc., manufacturers and sells products in two primary product lines, Acuity and Xact. Acuity sells products, solutions and services that includes laser and white light sensor distance. Xact includes satellite focused remote tank monitoring products.
SeaSpine Holdings is a medical technology company focused on the design, development and commercialization of surgical solutions for the treatment of patients with spinal disorders. The company's products include: orthobiologics, which include particulate and fibers-based demineralized bone matrices, collagen ceramic matrices, demineralized cancellous allograft bone and synthetic bone void fillers; and spinal implants, which consist of a line of products for spinal decompression, alignment, and stabilization. The company's development pipeline consists of modular minimally invasive surgery, additional applications for its NanoMetalene technology, and extensions of its orthobiologics product offerings.
Support.com is engaged in outsourced call center and direct-to-consumer and small business technical support solutions. The company provides outsourced call center tech support services, cloud-based call center software, and tech support and anti-malware software. The company delivers support solutions, including presale and post-sale support across all devices in the connected home. Designed for both the consumer and small and medium-sized businesses end-user markets, the company's programs include a range of services for connected devices, including pre-purchase concierge advice, device set-up and troubleshooting, inter-operability problem resolution, and virus and malware removal.
Synalloy is engaged in the following segments, the Metals segment and the Specialty Chemicals segment. The Metals segment manufactures welded pipe and tube, primarily from stainless steel, duplex, and nickel alloys; manufactures fiberglass and steel storage tanks; distributes hot finish, seamless, carbon steel pipe and tubing; and manufactures ornamental stainless steel tubing. The Specialty Chemicals segment manufactures lubricants, surfactants, defoamers, reaction intermediaries, and sulfated fats and oils, and provides chemical tolling manufacturing resources to global and regional companies and contracts with other chemical companies to manufacture certain pre-defined products.
Syros Pharmaceuticals is a biopharmaceutical company engaged in the non-coding regulatory region of the genome to develop a new wave of medicines that control the expression of genes. The company's primary product candidates are: SY-1425, a selective retinoic acid receptor alpha agonist that is used to treat acute myeloid leukemia patients; SY-1365, a selective inhibitor of cyclin-dependent kinase 7 (CDK7), that is being evaluated in a Phase 1 clinical trial in patients with advanced solid tumors; and SY-5609, a CDK7 inhibitor that can be administered orally, which is being evaluated in investigational new drug application, enabling preclinical studies.
Target Hospitality provides rental and hospitality services including: catering food services, maintenance, housekeeping, grounds-keeping, on-site security, overall workforce lodge management, and laundry service. The company serves clients in oil, gas, mining, alternative energy, government and immigrations sectors principally located in the West Texas, South Texas, Oklahoma and Bakken regions, as well as various linear-construction (pipeline and infrastructure) projects in the United States.
U.S. Concrete is a holding company. Through its subsidiaries, the company is engaged as a producer of ready-mixed and as a supplier of aggregates. The company's products comprised of: ready-mixed concrete, which products consist of proportioned mixes it produces and delivers in an unhardened plastic state for placement and shaping into designed forms at the job site; aggregates products, which sells these aggregates for use in commercial, industrial and public works projects in the markets they serve; and other, which includes the company's building materials stores, hauling operations, aggregates distribution terminals, a recycled aggregates operation and concrete blocks.
Vince Holding is a holding company. Through its subsidiaries, the company owns and operates the Vince business. Vince is an apparel and accessories brand. The company provides an array of women's and men's ready-to-wear, shoes, and capsule collection of handbags, and home for a global lifestyle. The company's segments include: Wholesale, which is comprised of sales to primary department stores and other stores in the U.S. and in select international markets, and also includes its licensing business related to its licensing arrangement for its women's and men's footwear line; and Direct-to-consumer, which includes its the company-operated retail and outlet stores and its e-commerce business.
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