Advanced Emissions Solutions provides emissions reductions technologies through consumables that utilize powdered activated carbon (PAC) and chemical based technologies, primarily serving the coal-fired power generation and industrial boiler industries. The company's operations consisted of two reportable segments: refined coal, which engages in equity method investments as well as royalty related to reduced emissions of both nitrogen oxide and mercury from coal; and Power Generation and Industrials, which sells consumable products that utilize PAC and chemical technologies as well as historically the sale of activated carbon injection and dry sorbent injection equipment systems.

Agilent Technologies is engaged in life sciences, diagnostics and applied chemical markets. The company's segments are: Life Sciences and Applied Markets Business, which provides instruments and software that enable customers to identify, quantify and analyze the physical and biological properties of substances and products; Diagnostics and Genomics Business, which includes the genomics, nucleic acid contract manufacturing and research and development, pathology, companion diagnostics, reagent partnership and biomolecular analysis businesses; and Agilent CrossLab Business, which spans the entire lab with its consumables and services portfolio to improve customer outcomes.

Agilysys is a provider of hospitality software. The company delivers technology solutions for gaming, hotels, resorts and cruise, corporate foodservice management, restaurants, universities, stadia and healthcare. The company provides solutions in the industry, including point of sales, property management, inventory and procurement, payments, and related applications, to manage the entire guest journey. The company is a developer and marketer of software enabled solutions and services to the hospitality industry, including software solutions fully integrated with third party hardware and operating systems; support, maintenance and subscription services; and other services.

Arcus Biosciences is a clinical-stage biopharmaceutical company focused on creating cancer immunotherapies. The company has four clinical-stage product candidates: AB928, which is an orally bioavailable, reversible antagonist of the adenosine 2a and adenosine 2b receptors; AB680, which is a reversible and selective inhibitor of the CD73 enzyme; AB122, which is a human antibody with similar binding affinity and other characteristics to the marketed anti-PD-1 antibodies pembrolizumab and nivolumab; and AB154, which is a humanized antibody that inhibits an immune checkpoint target involved in a pathway that plays both inhibitory and stimulatory roles in the immune system.

Axogen provides surgical solutions for physical damage or transection to peripheral nerves. The company's products include: Avance Nerve Graft, which is an off-the-shelf processed human nerve allograft for bridging severed peripheral nerves without the comorbidities associated with a second surgical site; Axoguard Nerve Connector, which is a porcine submucosa extracellular matrix (ECM) coaptation aid for tensionless repair of severed peripheral nerves; Axoguard Nerve Protector, which is a porcine submucosa ECM product used to wrap and protect injured peripheral nerves and reinforce the nerve reconstruction while preventing soft tissue attachments.

Caesars Entertainment is a holding company that provides casino-entertainment and hospitality services. The company's facilities include gaming offerings, food and beverage outlets, hotel and convention space, and non-gaming entertainment options. In addition to its brick and mortar assets, the company operates an online gaming business that provides real money games in certain jurisdictions and provides retail sports wagering in certain jurisdictions. The company's consolidated business is composed of five complementary businesses: casino entertainment, food and beverage, rooms and hotel, casino management services, and entertainment and other business operations, including mobile sports betting.

Capital Southwest is an internally managed closed-end, non-diversified management investment company. The company's investment objective is to produce risk-adjusted returns by generating current income from its debt investments and capital appreciation from its equity and equity related investments.

Castle Brands develops and markets various brands in the following beverage alcohol categories: rum, whiskey, liqueurs, and vodka. As of Mar 31 2018, the company distributed its products in all 50 U.S. states and the District of Columbia, in 13 primary international markets. The company markets the following brands, among others: Goslings rum?, Goslings Stormy Ginger Beer, Goslings Dark 'n Stormy? ready-to-drink cocktail, Jefferson's? bourbon, Jefferson's Reserve?, Jefferson's Ocean Aged at Sea?, Jefferson's Wine Finish Collection, Jefferson's The Manhattan: Barrel Finished Cocktail, Jefferson's Chef's Collaboration, Jefferson's Wood Experiment, and Jefferson's Presidential Select.

Del Frisco's Restaurant Group is a holding company. Through its subsidiaries, the company develops, owns and operates three restaurants: Del Frisco's Double Eagle Steakhouse (Double Eagle), Del Frisco's Grille (the Grille), and Sullivan's Steakhouse (Sullivan's). Double Eagle's menu includes steaks and a range of other offerings, including lamb, seafood, and side dishes and desserts. The Grille's menu is designed to appeal to business and casual diners and features steaks, various menu items and a selection of wines. Sullivan's is a restaurant with an open kitchen, live music and a bar area.

Dova Pharmaceuticals is a pharmaceutical company focused on acquiring, developing and commercializing drug candidates for diseases that are treated by specialist physicians, with an initial focus on addressing thrombocytopenia, a disorder characterized by a low blood platelet count. The United States Food and Drug Administration has approved DOPTELET (avatrombopag), which is an orally administered thrombopoietin receptor agonist for the treatment of thrombocytopenia in adult patients with chronic liver disease scheduled to undergo a procedure. The company is also conducting a trial in chemotherapy-induced thrombocytopenia.

Enphase Energy is a global energy technology company. The company designs, develops, manufactures and sells home energy solutions that connect energy generation, energy storage and control and communications management on one platform. The company's semiconductor-based microinverter converts energy at the individual solar module level and, combines with its proprietary networking and software technologies to provide energy monitoring and control. The Enphase Home Energy Solution with IQ consists of four primary components: Enphase microinverters, the AC Battery?, an Envoy gateway, and Enlighten cloud-based software.

Erie Indemnity is an attorney-in-fact for the subscribers (policyholders) at the Erie Insurance Exchange (Exchange), a reciprocal insurer that writes property and casualty insurance. The company's main function as attorney-in-fact is to perform policy issuance and renewal services on behalf of the subscribers at the Exchange. The company also acts as attorney-in-fact on behalf of the Exchange with respect to claims handling and investment management services, as well as the service provider for the claims handling, life insurance, and investment management services for its insurance subsidiaries. The company provides policy issuance and renewal services related to the sales, underwriting and issuance of policies.

Expeditors International of Washington provides global logistics services. As a third party logistics provider, the company purchases cargo space from carriers (such as airlines, ocean shipping lines, and trucking lines) on a volume basis and resells that space to its customers. The company provides a range of transportation services and customer solutions, such as customs brokerage, order management, transportation, warehousing and distribution, transit, cargo insurance, cargo monitoring and tracking, and other customized logistics and consulting solutions. The company's Project Cargo unit handles special project shipments that move via a single method or combination of air, ocean, and/or ground transportation.

Farmland Partners is a real estate company that owns and seeks to acquire farmland located in agricultural markets throughout North America. The company owns farms in Alabama, Arkansas, California, Colorado, Florida, Georgia, Illinois, Kansas, Louisiana, Michigan, Mississippi, Nebraska, North Carolina, South Carolina, South Dakota, Texas and Virginia. In addition, the main portion of the acres in the company's portfolio are used to grow primary crops, such as corn, soybeans, wheat, rice and cotton, with the balance used to grow crops, such as blueberries, vegetables, citrus, nuts and edible beans.

First Horizon National is a bank holding company. The company provides financial services primarily through its principal subsidiary, First Horizon Bank. The company's business segments include: regional banking, which provides investments, wealth management, financial planning, trust services and asset management, mortgage banking, credit card, and cash management; fixed income, which consists of fixed income securities sales, trading, underwriting, and strategies for institutional clients in the United States and abroad, as well as loan sales, portfolio advisory services, and derivative sales; and non-strategic, which includes run-off consumer lending activities and pre-2009 mortgage banking elements.

Flexion Therapeutics is a biopharmaceutical company focused on the discovery, development and commercialization of local therapies for the treatment of patients with musculoskeletal conditions, beginning with osteoarthritis (OA), a type of degenerative arthritis. The company has an approved product, ZILRETTA?, the extended-release, intra-articular (meaning in the joint), injection indicated for the management of OA knee pain. The company's pipeline program, FX201, is a gene therapy product candidate designed to stimulate the production of an anti-inflammatory protein, interleukin-1 receptor antagonist, providing at least one year of pain relief from OA of the knee.

New Media Investment Group owns, operates and invests in local media assets focused in small to mid-size markets. The company's main products include: daily newspapers; weekly newspapers, which publishe up to three times per week; shoppers, which are generally advertising-only publications; locally-focused websites, which extend the company's businesses onto the internet and mobile devices; business publications; UpCurve Cloud and ThriveHive digital marketing; and GateHouse Live. In addition to its main products, the company also produces publications that address specific local market interests such as recreation, sports, healthcare and real estate.

Great Lakes Dredge & Dock is a provider of dredging services. The company provides dredging services in the East, West, and Gulf Coasts of the U.S. and worldwide. The company operates in one operating segment, which is also the company's sole reportable segment and reporting unit. Dredging generally involves the enhancement or preservation of navigability of waterways or the protection of shorelines through the removal or replenishment of soil, sand or rock. Domestically, the company's work generally is performed in coastal waterways and deep water ports. The U.S. dredging market consists of four primary types of work: capital, coastal protection, maintenance and rivers and lakes.

Heritage Insurance Holdings is a property and casualty insurance holding company. Through its subsidiaries, the company writes personal residential property insurance for single-family homeowners and condominium owners, and rental property insurance in Alabama, Connecticut, Florida, Georgia, Hawaii, Massachusetts, New Jersey, New York, North Carolina, Rhode Island and South Carolina. The company also provides commercial residential insurance for Florida properties and is also licensed in Maryland, Mississippi, Pennsylvania, and Virginia. The company controls or manages substantially all aspects of insurance underwriting, customer service, actuarial analysis, distribution and claims processing and adjusting.

Home Bancorp is a bank holding company. Through its subsidiary, Home Bank, N.A., the company is primarily engaged in accepting deposits from the general public and using those funds to invest in loans and securities. These funds are primarily used for the origination of loans, including one-to four-family first mortgage loans, home equity loans and lines, commercial real estate loans, construction and land loans, multi-family residential loans, commercial and industrial loans and consumer loans. The company's deposits consist of checking, both interest-bearing and noninterest-bearing, money market, savings and certificate of deposit accounts.

Kandi Technologies Group is a producer and manufacturer of electrical vehicle products, electrical vehicle parts and off road vehicles for sale in the People's Republic of China and global markets. Co. conducts its business operations through its wholly-owned subsidiary, Zhejiang Kandi Vehicles Co., Ltd. and its subsidiaries. Co. has two main products: electric vehicle parts and off-road vehicles. Co. focuses on electrical vehicle parts production and supplies the joint venture company, Zhejiang Kandi Electric Vehicles Co., Ltd., with electrical vehicle parts. In addition, Co. produces and sells off-road vehicles, which are sold to domestic and international distributors or consumers.

Kingstone Companies is an insurance holding company. Through its wholly-owned subsidiary, Kingstone Insurance Company (KICO), the company provides property and casualty insurance products to individuals and small businesses. KICO is a licensed property and casualty insurance company in New York, New Jersey, Connecticut, Massachusetts, Pennsylvania, Rhode Island, Maine and New Hampshire. The company's product lines include: personal lines, which provide homeowners and dwelling fire multi-peril, cooperative/condominiums and personal umbrella policies; commercial liability, which provides businessowners policies; and livery physical damage, which writes for-hire vehicle physical damage only policies.

Las Vegas Sands is a developer of destination properties (Integrated Resorts) that feature accommodations, gaming, entertainment and retail malls, convention and exhibition facilities, restaurants and other amenities. The company owns and operates Integrated Resorts in Asia and the United States. Through its ownership of Sands China Ltd., the company owns and operates properties including The Venetian Macao Resort Hotel, Sands Cotai Central, The Parisian Macao, The Plaza Macao and Four Seasons Hotel Macao, Cotai Strip, and the Sands Macao. In Singapore, the company owns and operates the Marina Bay Sands. The company's Las Vegas Operating Properties includes The Venetian Resort Las Vegas and the Sands Expo Center.

Lilis Energy is an independent oil and gas company focused on the exploration, acquisition, development, and production of oil and natural gas reserves from properties in the Permian Basin. The company's operations are focused on the Delaware Basin of the Permian in Winkler, Loving, and Reeves Counties, TX and Lea County, NM.

Macquarie Infrastructure is a holding company. The company owns and operates a portfolio of businesses that provide services to other businesses, government agencies and individuals primarily in the U.S. The businesses the company owns and operate are: International-Matex Tank Terminals, which provides bulk liquid terminalling services to third parties in the U.S. and in Canada; Atlantic Aviation, which provides fuel, terminal, aircraft hangaring and other services primarily to owners and operators of general aviation jet aircraft at airports throughout the U.S.; and MIC Hawaii, which consist of energy company that processes and distributes gas and provides related services.

MaxLinear is a provider of radio frequency, analog, and mixed-signal communications systems-on-chip solutions for the connected home, wired and wireless infrastructure, and industrial and multi-market applications. The company's products are integrated into a range of electronic devices, including cable, terrestrial, and satellite video set-top boxes and gateways, cable DOCSIS data and voice gateways, hybrid analog and digital televisions, direct broadcast satellite outdoor units, optical modules for data center, metro, and long-haul transport network applications, RF transceivers and modem solutions, wireline connectivity devices, and power management and interface products.

Maxwell Technologies develops, manufactures and markets energy storage and power delivery products for transportation, industrial, and other applications. The company provides the following two product lines: Energy Storage, which consist of the company's ultracapacitor products that are energy storage devices that possess a combination of high power density, long operational life and the ability to charge and discharge; and High-Voltage Capacitors, which consist of the company's CONDIS? high-voltage capacitors that are used to ensure the safety and reliability of electric utility infrastructure and other applications involving transport, distribution and measurement of high-voltage electrical energy.

Meridian Bancorp is a bank holding company. Through its subsidiary, East Boston Savings Bank, the company provides a variety of deposit and loan products to individuals and businesses located in its primary market, which consists of Suffolk, Norfolk, Middlesex and Essex Counties, MA. The company accepts deposits from the general public and uses those funds to originate one- to four-family real estate, multi-family and commercial real estate, construction, commercial and industrial, and consumer loans, which it primarily holds for investment. The company's lending business also involves the purchase and sale of loan participation interests.

Newell Brands is a global marketer of consumer and commercial products. The company's segments include: Appliances and Cookware, which designs, manufactures, sources, markets and distributes a various line of household products; Food and Commercial, which designs, manufactures, sources, markets and distributes a various line of household products; Home and Outdoor Living, which designs, manufactures, sources, markets and distributes home fragrance and home security products; and Learning and Development, which designs, manufactures, sources, markets and distributes writing instruments, including markers and highlighters, pens and pencils.

Nicholas Financial is a holding company. Through its subsidiary, Nicholas Financial, Inc., the company is engaged primarily in acquiring and servicing automobile finance installment contracts (Contracts) for purchases of used and new automobiles and light trucks. In addition, the company also originates direct consumer loans (Direct Loans) and sells consumer-finance related products. For Automobile Finance Business - Contracts, the company is engaged in the business of providing financing programs, on behalf of purchasers of used cars and light trucks. For Contract Procurement, the Contracts purchased by the company is for used vehicles. For Direct Loans, the loans originated directly between the company and the consumer.

Northeast Bancorp is a bank holding company. Through its Northeast Bank subsidiary, the company provides a range of banking services to individual and corporate customers and conducts loan purchasing and origination activities. The company conducts its loan-related activities through three primary channels: the Loan Acquisition and Servicing Group, the Small Business Administration Division, and Community Banking Division. The company's deposit products consist of demand deposit, Negotiable Order of Withdrawal, money market, savings and certificate of deposit accounts. The company's online deposit program, ableBanking, provides an additional channel through which to obtain primary deposits.

Ocular Therapeutix is a biopharmaceutical company focused on the formulation, development and commercialization of therapies for diseases and conditions of the eye using its proprietary, bioresorbable hydrogel platform technology. The company has product candidates in clinical and preclinical development to treat post-surgical ocular pain and inflammation, allergic conjunctivitis, dry eye disease, among other conditions. The company's drug application, DEXTENZA? (dexamethasone ophthalmic insert) 0.4mg is for intracanalicular use for the treatment of ocular pain following ophthalmic surgery. The company is also assessing the potential use of its hydrogel platform technology in other areas of the body.

Odonate Therapeutics is a pharmaceutical company focused on the development of therapeutics that improve and extend the lives of patients with cancer. The company's initial focus is on the development of tesetaxel, an investigational, orally administered chemotherapy agent that belongs to a class of drugs known as taxanes, which are used in the treatment of cancer. In patients with metastatic breast cancer, tesetaxel was shown to have single-agent antitumor activity in two multicenter, Phase 2 studies. The company is conducting a multinational, multicenter, randomized, Phase 3 study in patients with locally advanced or metastatic breast cancer, known as CONTESSA.

Opko Health is a healthcare company. The company manages two segments: Diagnostics, which provides laboratory testing services utilized by healthcare providers in the detection, diagnosis, evaluation, monitoring, and treatment of diseases, including esoteric testing, molecular diagnostics, anatomical pathology, genetics, women's health and correctional healthcare; and Pharmaceutical, which includes Rayaldee for the treatment of secondary hyperparathyroidism in adults with chronic kidney disease (CKD) and vitamin D insufficiency, and Alpharen (Fermagate Tablets) for the treatment of hyperphosphatemia in CKD patients requiring regular hemodialysis.

OptiNose is pharmaceutical company focused on the development and commercialization of products for patients treated by ear, nose and throat and allergy specialists. The company's first commercial product, XHANCE? (fluticasone propionate) nasal spray, 93 mcg, is a therapeutic utilizing its key Optinose Exhalation Delivery System (EDS) that delivers a topically-acting corticosteroid for the treatment of chronic rhinosinusitis with nasal polyps and, if approved, chronic rhinosinusitis without nasal polyps (chronic sinusitis). The company's other candidate includes OPN-300, which combines an Optinose EDS with oxytocin to target two orphan indications: Prader-Willi syndrome and autism spectrum disorder.

Provident Financial Services is a holding company. Through its subsidiary, Provident Bank (the Bank), the company accepts deposits from the public and businesses primarily in the areas surrounding its banking offices and uses those funds, together with funds generated from operations and borrowings, to originate commercial real estate loans, commercial business loans, residential mortgage loans, and consumer loans. The Bank also invests in mortgage-backed securities and other permissible investments. The company's deposit products include savings accounts, checking accounts, interest-bearing checking accounts, money market deposit accounts and certificate of deposit accounts.

Raven Industries is a technology company providing a range of products to customers within the industrial, agricultural, geomembrane, construction, commercial lighter-than-air and aerospace/defense markets. The company has three reportable segments: Applied Technology Division, which includes application controls, GPS-guidance steering systems, field computers, automatic boom controls, information management tools, and injection systems; Engineered Films Division, which produces plastic films and sheeting for geomembrane, agricultural, construction, and industrial applications; Aerostar Division, which provides products that include high-altitude stratospheric balloons and radar systems.

RealNetworks is a provider of network-delivered digital media applications and services. The company also develops and markets software products and services that enable the creation, distribution and consumption of digital media, including audio and video. The company's segments include: Consumer Media, in which the company is primarily engaged in the licensing of its portfolio of video codecs; Mobile Services, which consists of the digital media services the company provides to mobile and online service providers as software as a service offerings; and Games, which is focused on the development, publishing, and distribution of casual games, which are provided via mobile devices, digital downloads, and subscription play.

Rigel Pharmaceuticals is a biotechnology company focused on discovering, developing and providing small molecule drugs that improve the lives of patients with immune and hematologic disorders, cancer and rare diseases. The company's research focuses on signaling pathways that are critical to disease mechanisms. The company's approved product is TAVALISSE? (fostamatinib disodium hexahydrate), an oral spleen tyrosine kinase inhibitor, for the treatment of adult patients with chronic immune thrombocytopenia who have had an insufficient response to a previous treatment. In addition, the company has product candidates in development with partners BerGenBio ASA, Daiichi Sankyo, Aclaris Therapeutics, and AstraZeneca AB.

Safety, Income and Growth acquires, owns, manages, finances and capitalizes ground net leases, or GNLs. GNLs generally represent ownership of the land underlying commercial real estate projects that is net leased by the fee owner of the land to the owners/operators of the real estate projects built thereon.

Sally Beauty Holdings is a holding company. Through its subsidiaries, the company is an international retailer and distributor of beauty supplies with operations in North America, South America and Europe. The company's business segments are: Sally Beauty Supply (SBS), which is an open-line retailer of beauty supplies; and Beauty Systems Group (BSG), which is a beauty supply distributor. SBS stores and websites carry beauty supplies, featuring beauty products across product categories including hair color and care, and skin and nail care. The company features beauty products in its BSG stores across product categories including hair color and care, skin and nail care, styling tools and other beauty items.

Scientific Games is a developer of technology-based products and services and associated content for the worldwide gaming, lottery and interactive gaming industries. The company's portfolio activities primarily includes supplying gaming machines and game content, casino-management systems and table game products and services to licensed gaming entities; providing instant and draw-based lottery products, lottery systems and lottery content and services to lottery operators; providing social casino solutions to retail consumers and regulated gaming entities; and providing a suite of digital real-money gaming and sports wagering solutions, distribution platforms, content, products and services.

SRC Energy is an independent oil and gas company engaged in the acquisition, development, and production of oil, natural gas, and natural gas liquids in the D-J Basin. It contains hydrocarbon-bearing deposits in several formations, including the Niobrara, Codell, Greenhorn, Shannon, Sussex, J-Sand, and D-Sand. The company's oil and natural activities are focused in the Wattenberg Field, in Weld County, CO, an area that covers the western flank of the D-J Basin. The company is focused on the horizontal development of the Codell formation as well as the three benches of the Niobrara formation, which are all characterized by high liquids content.

Star Group is a home heating oil and propane distributor and services provider. The company sells home heating oil and propane to full service residential and commercial customers and on a delivery only basis. The company also sells gasoline and diesel fuel to customers. The company installs, maintains, and repairs heating and air conditioning equipment and to a lesser extent provides these services outside its heating oil and propane customer base including service contracts for natural gas and other heating systems. The company conducts its business through an operating subsidiary, Petro Holdings, Inc., utilizing several local brand names, such as Petro Home Services, Meenan, and Griffith Energy Services, Inc.

Titan International is a wheel, tire, and undercarriage industrial manufacturer and supplier servicing customers across the globe. The company has three segments: agricultural, which provides agricultural rims, wheels, tires, and undercarriage systems and components are manufactured for use on various agricultural equipment, including tractors, combines, skidders, plows, and planters; earthmoving/construction, which manufactures rims, wheels, tires, and undercarriage systems and components for various types of off-the-road earthmoving, mining, military, construction and forestry equipment; and consumer, which manufactures bias truck tires in Latin America and light truck tires in Russia.

Trio-Tech International provides third-party semiconductor testing and burn-in services primarily through its laboratories in Asia. At or from its facilities, the company also designs, manufactures and markets equipment and systems to be used in the testing and production of semiconductors, and distributes semiconductor processing and testing equipment manufactured by other vendors. The company operates in four segments; the testing service industry (which performs structural and electronic tests of semiconductor devices), the designing and manufacturing of equipment distribution of various products from other manufacturers in Singapore and Asia and the real estate segment in China.

Varex Imaging is a designer and manufacturer of X-ray imaging components. In its Medical business segment, the company designs, manufactures, sells and services X-ray imaging components for use in a range of radiographic or fluoroscopic imaging applications including computed tomography, mammography, oncology, cardiac, surgery, dental, and computer-aided detection. In its Industrial business segment, the company designs, manufactures, sells and services X-ray imaging products for use in several markets, including security applications, such as cargo screening at ports and borders and baggage screening at airports, and nondestructive testing and inspection applications used in several other markets.

Veeco Instruments is a manufacturer of semiconductor and thin film process equipment. The company's system products include: Metal Organic Chemical Vapor Deposition Systems, Advanced Packaging Lithography, Precision Surface Processing Systems (Wet Etch and Clean), Laser Annealing Systems, Ion Beam Deposition and Etch Systems, Molecular Beam Epitaxy Systems, 3D Wafer Inspection Systems, and Atomic Layer Deposition and Other Deposition Systems. The company's systems are used in the production of microelectronic components, including light emitting diodes, micro-electro mechanical systems, radio frequency filters and amplifiers, power electronics, thin film magnetic heads, and other semiconductor devices.

WestRock is a provider of paper and packaging solutions for consumer and corrugated packaging markets. The company partners with its customers to provide paper and packaging solutions. The company's operating and business locations are in North America, South America, Europe, Asia and Australia. The company's segments include: Corrugated Packaging, which consists of the company's containerboard mills, corrugated packaging and distribution operations, as well as its merchandising displays and recycling procurement operations; Consumer Packaging, which consists of the company's consumer mills, food and beverage and partition operations; and Land and Development, which sells real estate primarily in the Charleston, SC region.

Zynerba Pharmaceuticals is a clinical stage specialty pharmaceutical company focused on the development of pharmaceutically-produced transdermal cannabinoid therapies for rare and near-rare neuropsychiatric disorders, including Fragile X syndrome (FXS), Autism Spectrum Disorder (ASD), 22q11.2 Deletion Syndrome, and a heterogeneous group of rare and ultra-rare epilepsies known as developmental and epileptic encephalopathies (DEE). The company is evaluating Zygel?, a patent-protected transdermal cannabidiol gel for the treatment of FXS, DEE and ASD. Zygel is being developed as a clear gel that is designed to provide consistent, controlled drug delivery with once- or twice-daily dosing.