Aptinyx is a clinical-stage biopharmaceutical company focused on the discovery, development, and commercialization of synthetic small molecules for the treatment of brain and nervous system disorders. The company's product candidates comprised of: NYX 2925, which is a small molecule N-methyl-D-aspartate receptors (NMDAr) modulator being developed for the treatment of chronic pain; NYX-783, which is a small-molecule NMDAr modulator in development for the treatment of post-traumatic stress disorder; NYX-458, which is a small-molecule NMDAr modulator in development for the treatment of Parkinson's disease cognitive impairment; and AGN-241751, which is for the treatment of depressive disorder.

BioDelivery Sciences International is a pharmaceutical company with a focus on patients living with chronic pain and associated conditions. The company has built a portfolio of products that includes utilizing its proprietary BioErodible MucoAdhesive drug-delivery technology to develop and commercialize new applications of proven therapies aimed at addressing unmet medical needs. The company's product candidates include: BELBUCA for the management of pain severe enough to require long-term opioid treatment and for which alternative treatment options are inadequate; and Symproic for the management of opioid-induced constipation in adult patients with chronic non-cancer pain.

Brightcove is a provider of cloud-based services for video. The company's products and services include: Brightcove Video Cloud, which is an online video platform to publish and distribute video to Internet-connected devices; Brightcove Zencoder, which is a cloud-based video encoding service; Brightcove SSAI, which is a cloud-based ad insertion and video stitching service; Brightcove Player, which is a cloud-based service for creating and managing video player experiences; Brightcove OTT Flow, which deploy direct-to-consumer, live and on-demand video services across platforms; Brightcove Video Marketing, which is an offering of Video Cloud, Brightcove Gallery (Gallery), and Brightcove Social.

Cidara Therapeutics is a biotechnology company focused on the discovery, development and commercialization of anti-infectives for the treatment and prevention of diseases. The company is developing a pipeline of product and development candidates, with a focus on fungal and infections. The company's primary product candidate is rezafungin acetate, an intravenous formulation of a echinocandin. Rezafungin is being developed as a once-weekly therapy for the first-line treatment and prevention of fungal infections. In addition, the company is using its Cloudbreak? platform to develop Antiviral Fc-Conjugates, for the prevention and treatment of influenza and other infections.

eHealth is a health insurance marketplace with a technology and service platform that provides consumer engagement, education and health insurance enrollment solutions. The company operates its business in two segments: Medicare, which markets a selection of Medicare-related health insurance plans, and to a lesser extent, ancillary products such as dental and vision insurance, to its Medicare-eligible customers; and Individual, Family and Small Business, which markets individual and family health insurance and small business health insurance plans through its ecommerce platforms (www.eHealth.com and www.eHealthInsurance.com).

Heska sells veterinary and animal health diagnostic and specialty products. The company's segments are: Core Companion Animal, which includes, primarily for canine and feline use, Point of Care laboratory instruments and consumables, digital imaging diagnostic instruments, software and services, local and cloud-based data services, allergy testing and immunotherapy, and single use offerings such as in-clinic diagnostic tests and heartworm preventive products; and Other Vaccines and Pharmaceuticals, which includes private label vaccine and pharmaceutical production, primarily for cattle but also for other species including equine, porcine, avian, feline and canine.

HollyFrontier is a petroleum refiner that produces products such as gasoline, diesel fuel, jet fuel, other lubricant products, and specialty and modified asphalt. The company's segments are: Refining, which involves the purchase and refining of crude oil and wholesale and marketing of refined products; Lubricants and Specialty Products, which includes the production of lubricant products such as base oils, white oils, other products and finished lubricants; and the company's subsidiary, Holly Energy Partners, L.P., which owns and operates logistics and refinery assets consisting of petroleum product and crude oil pipelines, terminals, tankage, loading rack facilities and processing units.

NAPCO Security Technologies is a manufacturer of security products, encompassing access control systems, door-locking products, intrusion and fire alarm systems and video surveillance products for commercial and residential use. The company also provides wireless communication service for intrusion and fire alarm systems. These products are used for commercial, residential, institutional, industrial and governmental applications, and are sold worldwide principally to independent distributors, dealers and installers of security equipment. The company also markets peripheral and related equipment manufactured by other companies.

National Bank Holdings is a bank holding company. Through its subsidiary, NBH Bank, the company's primary business is to provide a range of banking products and financial services to its commercial, business and consumer clients, who are primarily located in Colorado, the greater Kansas City region, New Mexico, Texas and Utah. The company provides a variety of products and services in the following areas: Commercial and Specialty Banking, which focuses on small- and medium-sized businesses and provides a suite of loan, deposit and treasury management products and services; and Business, Residential and Consumer Banking, which provides a complement of loan, deposit and online and mobile banking solutions.

OGE Energy is a holding company. Through its subsidiaries, the company is an energy and energy services provider providing physical delivery and related services for both electricity and natural gas primarily in the south central United States Co. conducts these activities through two business segments: electric utility, which generates, transmits, distributes and sells electric energy in Oklahoma and western Arkansas; and natural gas midstream operations, which consist of the company's investment in Enable Midstream Partners, LP, which is primarily engaged in the business of gathering, processing, transporting and storing natural gas.

Safehold is a holding company. Through its subsidiaries, the company operates its business through one segment by acquiring, managing and capitalizing ground leases. Ground leases generally represent the ownership of land underlying commercial real estate properties, which are leased on a long-term basis (base terms are 30 to 99 years, often with tenant renewal options) by the land owner to a tenant that owns and operates the building on top of the land, or what the company refer to as a Safehold?.

Twilio provides a cloud communications platform that enables developers to build, scale and operate communications within their software applications via the company's Application Programming Interfaces (APIs). The company's platform consists of three layers: Engagement Cloud, which provides functionality for a specific purpose, such as two-factor authentication or a contact center; Programmable Communications Cloud, which provides a range of products that enables developers to embed voice, messaging and video capabilities into their applications; and Super Network, which contains a set of API's giving the company's customers access to components of its platform.