Gossamer Bio is a clinical-stage biopharmaceutical company focused on discovering, acquiring, developing and commercializing therapeutics in immunology, inflammation and oncology. The company has four clinical-stage product candidates: GB001 (Prostaglandin D2 receptor 2 Antagonist), which is for the treatment of moderate-to-severe eosinophilic asthma and other allergic conditions; GB002 (Platelet-derived growth factor Receptor Kinase Inhibitor), which is for the treatment of pulmonary arterial hypertension; GB004 (Hypoxia inducible factor-1a Stabilizer), which is for the treatment of inflammatory bowel disease; and GB1275 (CD11b Modulator), which is for the treatment of oncology indications.
Selecta Biosciences is a biopharmaceutical company using its ImmTOR? platform, designed to induce tolerance to biologic therapies that would otherwise be limited by immunogenicity to treat rare and serious diseases. The company's product candidate, SEL-212, is a combination of a therapeutic uricase enzyme (pegadricase) and its ImmTOR platform that is designed to control serum uric acid levels in patients with chronic refractory gout through monthly administration. The company is applying its ImmTOR platform to mitigate the formation of anti-drug antibodies when dosing gene therapy. The company's investigational gene therapy program targets the treatment of rare genetic diseases, including methylmalonic acidemia.
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