Caladrius Biosciences is a late-stage therapeutics development biopharmaceutical company. The company's product candidates include three developmental treatments for cardiovascular diseases based on its CD34+ cell therapy platform: CLBS12, in Phase 2 and eligible for early conditional approval in Japan for the treatment of critical limb ischemia; CLBS14-CMD, in Phase 2 in the United States for the treatment of coronary microvascular dysfunction; CLBS14-NORDA for no-option refractory disabling angina and one autoimmune product candidate, CLBS03, an ex vivo expanded polyclonal T regulatory cell therapy for the treatment of recent-onset Type 1 diabetes.
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