Cara Therapeutics is a clinical-stage biopharmaceutical company focused on developing and commercializing new chemical entities with a primary focus on pruritus as well as pain by selectively targeting peripheral kappa opioid receptors. The company is developing a proprietary class of product candidates, led by KORSUVA (CR845/difelikefalin), a kappa opioid receptor agonist that targets the body's peripheral nervous system, as well as certain immune cells. The company's primary product candidate, CR845/difelikefalin, is a chemical entity, which is designed to selectively stimulate kappa, rather than mu, and delta opioid receptors outside of the CNS.
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