Cyclacel Pharmaceuticals is a clinical-stage biopharmaceutical company. The company utilizes its knowledge in cell cycle, transcriptional regulation and deoxyribonucleic acid (DNA) damage response biology in cancer cells to develop targeted medicines for cancer and other serious diseases. The company's Cyclin Dependent Kinase (CDK) Inhibitors are a family of enzymes discovered as regulators of the cell cycle, but also provide pivotal functions in the regulation of transcription, DNA repair and metastatic spread. Seliciclib, the company's primary CDK inhibitor, is being evaluated in an all-oral Phase 1/2 combination study with the company's sapacitabine in patients with BRCA mutations.
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