Jounce Therapeutics is a clinical stage immunotherapy company dedicated to transforming the treatment of cancer by developing therapies that enable the immune system to attack tumors. The company's product candidates include: vopratelimab, which is a clinical stage monoclonal antibody that binds to and activates the Inducible T cell CO-Stimulator, a protein on the surface of certain T cells commonly found in various solid tumors; JTX-4014, which is a clinical-stage anti-PD-1 antibody that the company is developing primarily for use in combination with future product candidates; and JTX-8064, which is an antibody that binds to LILRB2, a cell surface receptor expressed on macrophages.
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