FibroGen is a biopharmaceutical company engaged in discovering, developing and commercializing a pipeline of therapeutics. The company applies its capability in hypoxia-inducible factor (HIF) and connective tissue growth factor (CTGF) biology to develop medicines for the treatment of anemia, fibrotic disease, and cancer. Roxadustat, the company's primary product, is an inhibitor of HIF prolyl hydroxylase that acts by stimulating the body's natural pathway of erythropoiesis, or red blood cell production. Pamrevlumab is the company's human monoclonal antibody that inhibits the activity of CTGF, a central mediator and key common element in the progression of fibrotic and fibro-proliferative diseases.
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