ContraFect is a clinical-stage biotechnology company focused on discovering, differentiated biologic therapeutics and developing them for the treatment of life-threatening infectious diseases, including those caused by drug-resistant pathogens. The company's program, CF-301 (exebacase), is an investigational lysin targeting Staph aureus, including methicillin-resistant strains, which causes serious infections such as bacteremia, pneumonia and osteomyelitis. Exebacase is being studied in a Phase 2 superiority study to evaluate its safety and pharmacokinetics when used in addition to standard of care antibiotics for the treatment of Staph aureus bacteremia, including endocarditis in adult patients.
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