Evaxion to present novel AI-based polio vaccine design concepts at the World Vaccine Congress
- Using its pioneering AI-platform, AI-Immunology™, Evaxion has, in collaboration with the Gates Foundation, developed novel design concepts for polio vaccines potentially superior to those currently used
- The AI-Immunology™ concepts include hybrid capsid designs and de novo designed B-cell antigen approaches
- Despite polio vaccines being available for decades, the highly infectious viral disease continues to pose a global health risk
- Evaxion will also present data from its EVX-V1 vaccine program targeting cytomegalovirus at the World Vaccine Congress
COPENHAGEN, Denmark, March 30, 2026 - Evaxion A/S (NASDAQ: EVAX) (“Evaxion”), a clinical-stage TechBio company developing novel vaccines with its pioneering AI-Immunology™ platform, has in collaboration with the Gates Foundation developed novel and potentially superior concepts for design of vaccines to combat polio. These concepts, and the underlying research, will be presented at the World Vaccine Congress taking place in Washington D.C. from March 31 to April 2, 2026.
Current polio vaccines are based on inactivated or attenuated versions of the virus. While these vaccines are effective, they each have shortcomings in certain settings. Thus, it has been a long-standing - but so far unreachable - goal to create a novel polio vaccine that combines the strongest aspects of the existing vaccines.
To achieve this, Evaxion has deployed AI-Immunology™ to develop novel vaccine design concepts for a next-generation polio vaccine, which may enhance the chances of completing and sustaining polio eradication once and for all.
“These new polio vaccine design concepts are great examples of how AI-Immunology™ enables novel approaches to diseases for which adequate treatment options do not exist despite decades of research. We are excited to have applied the platform within a new viral disease, further validating its capability and scalability. Initial results support further development of the new concepts, representing another potential collaboration opportunity for us,” says Birgitte Rønø, CSO of Evaxion.
Evaxion will also present data from its EVX-V1 program at the World Vaccine Congress. EVX-V1 targets Cytomegalovirus (CMV). AI-Immunology™ has discovered novel CMV antigens and EVX-V1 is a next-generation, multi-component vaccine program combining these novel AI-discovered antigens with AI-optimized versions of established CMV vaccine antigens. This broader multi-targeted strategy is expected to strengthen the protective potential of the future vaccine.
Presentations details:
Presentation title: Designing a novel poliovirus vaccine using AI-Immunology™
Session: Emerging & re-emerging diseases
Location: Room 202A
Date/Time: April 1, 2026, at 16:40 ET
Presenter: Thomas Trolle, PhD, Director, Bioinformatics at Evaxion
Abstract title: AI-powered target discovery for a novel CMV vaccine
Session: Emerging & re-emerging Diseases
Location: Room 202A
Date/Time: April 2, 2026, at 10:25 ET
Presenter: Pär Comstedt, VP, Infectious disease vaccine development at Evaxion
Contact information
Evaxion A/S
Mads Kronborg
Vice President, Investor Relations & Communication
About Evaxion
Evaxion is a pioneering TechBio company based upon its proprietary, clinically validated and scalable AI platform, AI-Immunology™. The platform harnesses the power of artificial intelligence to decode the human immune system and develop novel vaccine candidates for cancer and infectious diseases.
With AI-Immunology™ we conduct rapid, efficient and high-quality target discovery, drug design and development. Our team of +40 experts covers the entire value chain from target discovery to clinical development
We have developed a clinical pipeline of both personalized and off-the-shelf cancer vaccine candidates as well as prophylactic vaccine candidates for infectious diseases. All our candidates address high unmet medical needs, reflecting our commitment to transforming patients’ lives by providing innovative and targeted treatment options.
For more information about Evaxion, AI-Immunology™ and our pipeline, please visit our .
Forward-looking statement
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