Edison Investment Research - Midatech Pharma (MTPH) Midatech Pharma - Planned dose-escalation commences in rGBM study

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Edison Investment Research

Sean Conroy

Midatech Pharma - Planned dose-escalation commences in rGBM study

Midatech has announced that following the completion of one month of treatment for the first patient enrolled in the MAGIC-G1 study (at a dose of 60uM), the Data Safety Monitoring Board (DSMB) has recommended dose escalation to 90uM (expected to be the target therapeutic dose for MTX110). MAGIC-G1 is an open-label, Phase I study designed to evaluate the feasibility and safety of MTX110 in recurrent glioblastoma (rGBM) using a convection-enhanced delivery (CED) system. However, we note that continued progression of this study will be contingent on the successful conclusion of the announced Bioasis deal and US$9.6m fund-raising, both of which require shareholder authorisation. Approval and completion of these is critical path for Midatech. The company states that it has a cash balance of £2.6m (as of 5 January 2023), which is only sufficient to fund operations to mid-March 2023.

13/01/2023 1 EN

Underlying

Midatech Pharma

Midatech Pharma is a holding company. Through its subsidiaries, Co. is engaged as a specialty pharmaceutical company focused on the development and commercialization of multiple therapeutic products, using its nanomedicine and sustained release technologies, to enhance the delivery of medicines in major diseases with high unmet medical needs. These diseases include diabetes, certain cancers such as liver, ovarian and brain (glioblastoma) and neurological/ophthalmologic conditions. Co.'s two platform technologies are designed to enable targeted delivery and sustained release of existing therapeutic drugs to the "right place" at the "right time."

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GB00BKT14T00 London Stock Exchange United Kingdom

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Edison Investment Research

Edison is an investment research and advisory company, with offices in North America, Europe, the Middle East and AsiaPac. The heart of Edison is our world renowned equity research platform and deep multi-sector expertise. At Edison Investment Research, our research is widely read by international investors, advisors and stakeholders. Edison Advisors leverages our core research platform to provide differentiated services including investor relations and strategic consulting.

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Analysts

Sean Conroy

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Midatech Pharma - Planned dose-escalation commences in rGBM study

Biodexa Pharmaceuticals - Pivoting out of a challenging FY22

Midatech Pharma - Development pipeline expands with MTD217

Hybridan Small Cap Feast 08/03/22

Manx Financial Group - Termination of coverage

musicMagpie - Termination of coverage

Topps Tiles - Accelerating growth through Q125

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