Hardman & Co Research: Diurnal (DNL): … and more to come (news flow)
Diurnal (DNL) is a commercial-stage specialty pharmaceutical company focused on diseases of the endocrine system. Its two lead products are targeting rare conditions where medical need is currently unmet, with the aim of building a long-term ‘Adrenal Franchise’. Its first drug, Alkindi, is being rolled out through key European markets, and sales exceeded £1.1m in 1H’20. Despite unexpected Phase III trial results, positive feedback from the EMA has opened a pathway for regulatory submission of Chronocort for adult CAH and AI in Europe. Discussions with potential US partners for both products are also expected to crystallise in the first half of calendar 2020.Diurnal Group is a pharma company developing products for the life-long treatment of chronic endocrine conditions. Co. is focused on addressing clinical and patient needs in hormone replacement, initially by developing and marketing products for the rare orphan diseases congenital adrenal hyperplasia and adrenal insufficiency. Co.'s products include Infacort®, an immediate-release hydrocortisone preparation targeting Adrenal Insufficiency (including Congenital Adrenal Hyperplasia) in children under six years of age in Europe and 16 years of age in the U.S.; and Chronocort®, a modified-release hydrocortisone preparation, initially targeting Congenital Adrenal Hyperplasia in adult patients.
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