Report

Verona Pharma (VRP.L) Trial update MAD clinical data improve the probability of success

Verona Pharma is developing first-in-class drugs that treat unmet medical needs in
respiratory disease. RPL554 is being fast-tracked to commercialisation by focusing on
a $3.2bn market segment poorly serviced by existing drugs. Key Phase II trial results
are due to be announced in Q3 2015. There remains a significant mis-match between
the current EV (£47m) and a potential inflection point on positive Phase II data in Q3
2015, when considering that median valuations for Phase II respiratory assets have
headline valuations of $285m (£190m), or 19p per share.
Underlying
Verona Pharma

Verona Pharam a clinical stage biopharmaceutical company focused on developing and commercialising therapeutics for the treatment of respiratory diseases with significant unmet medical needs. Co.'s product candidate, RPL554, is an inhaled, dual inhibitor of the enzymes phosphodiesterase 3 and 4, that acts as both a bronchodilator and an anti-inflammatory agent in a single compound. Co. is developing RPL554 for the treatment of patients with chronic obstructive pulmonary disease, as well as for the treatment of cystic fibrosis, a fatal inherited disease. Co. may also explore, alone or with a collaborator, the development of RPL554 to treat asthma and other respiratory diseases.

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Hardman & Co
Hardman & Co

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