Mesoblast’s Latest Trial Data Offers a Mixed Outlook; Reducing our FVE to AUD 2.35
No-moat Mesoblast’s latest trial data for a key treatment disappointed the market and calls into the question potential efficacy in tangential areas. The company reported the results of its 159-patient Phase 2b trial for MPC-150-IM usage in end-stage heart failure patients implanted with a left ventricular assist devise, or LVAD. While the therapy achieved a significant reduction in major gastrointestinal bleeding episodes, which the U.S. FDA noted was a clinically meaningful outcome, the impact...Mesoblast is engaged in the development of regenerative medicine products. Co. has leveraged its proprietary technology platform, based on specialized cells known as mesenchymal lineage adult stem cells ("MLCs"), to establish a portfolio of late-stage product candidates. Co.'s allogeneic, "off the shelf" product candidates target advanced stages of diseases with high, unmet medical needs including cardiovascular conditions, orthopedic disorders, immunologic and inflammatory disorders and oncology and hematologic conditions. Each MLC-derived product candidate has technical characteristics, target indications, reimbursement strategy, commercialization potential, and partnering opportunities.
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