ImmunoGen is a clinical-stage biotechnology company focused on developing antibody-drug conjugates (ADCs). An ADC with the company's proprietary technology comprises an antibody that binds to a target found on tumor cells and is conjugated to one of its anti-cancer agents as a payload to kill the tumor cell once the ADC has bound to its target. The company's main program is mirvetuximab soravtansine, an ADC targeting folate-receptor alpha, a cell-surface protein overexpressed in a number of epithelial tumors, including ovarian, endometrial, and non-small-cell lung cancers. The company is developing IMGN632 in clinical trials for patients with acute myeloid leukemia and blastic plasmacytoid dendritic cell neoplasm.
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