Mereo BioPharma: H120 results and corporate review
Mereo BioPharma is progressing the promising anti-TIGIT antibody, etigilimab, into Phase Ib/II trials for multiple solid tumour types in Q420 and intends to host an investor webinar focusing on this asset in a similar timeframe. Partnering discussions for setrusumab (osteogenesis imperfecta, OI), are ongoing with options sought to retain certain commercialisation rights. Clinical trials are underway again, with Phase II data for alvelestat in anti-alpha trypsin deficiency (AATD) is expected in H221. Financing options for acumapimod and leflutrozole are also being explored. Although its early stage means its contribution to our rNPV model is currently modest, success with etigilimab would be transformative for the company. Using conservative assumptions our current valuation is 101p/share or $5.06/ADS (fully diluted).Mereo Biopharma Group is engaged in the research and development of novel biopharmaceuticals for the treatment of rare and specialty diseases. Co. operates through three segment which are the respiratory unit, endocrinology disorders unit, orphan diseases unit. Respiratory unit develops drugs to treat respiratory diseases. Endocrinology disorders unit develops drugs to treat endocrine disorders. Orphan diseases unit develops drugs to treat various orphan diseases. Co. has two products which called BPS-804 and BGS-649.
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