Trinity Delta Lighthouse: Scancell
Trinity Delta view: The award of £2m to fund the COVIDITY Phase I study is welcome validation of the value of Scancell’s vaccine expertise. Whilst unlikely to be the first effective vaccine to market, its targeting of dendritic cells and ability to stimulate high avidity and potent T cell responses means it could provide a longer lasting and effective response through inducing both durable T cell responses and virus neutralising antibodies. The early nature of the project means that we do not include it in our current £83.7m valuation, equivalent to 13.3p/share (11.5p/share fully diluted), and so any success would represent additional upside.Scancell Holdings is engaged in the discovery and development of novel vaccines for the treatment of cancer based on its proprietary immuno-oncology platforms, ImmunoBody®, and Moditope®. Co.'s ImmunoBody® consist of SCIB1 melanoma vaccine, and SCIB2 lung cancer vaccine. Co. has a collaboration partnership to evaluate the use of its SCIB2 to treat non-small cell lung cancer. Co.'s Moditope® technology is a vaccine platform that targets neo-epitopes to overcome immune suppression induced by tumour cells. Co.'s Moditope® product, Modi-1 consists of two citrullinated vimentin peptides and one citrullinated enolase peptide for the treatment of breast cancer, ovarian cancer and sarcoma.
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