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Maria Vara ... (+2)
  • Maria Vara
  • Oscar Haffen Lamm

End of coverage

From 5th February, we will no longer include in our research universe:Adaptimmune, ALK, argenx, Autolus, Cellectis, Galapagos, Hansa Biopharma, Heidelberg Pharma, Immatics, Immunocore, Ipsen, Moonlake Immunotherapeutics, Pharvaris, UCB, Vivoryon Therapeutics, Zealand Pharma, Nicox, GenSight Biologi

Adaptimmune Therapeutics Plc: 4 directors

Four Directors at Adaptimmune Therapeutics Plc sold 59,468 shares at between 0.847USD and 0.848USD. The significance rating of the trade was 52/100. Is that information sufficient for you to make an investment decision? This report gives details of those trades and adds context and analysis to them such that you can judge whether these trading decisions are ones worth following. Included in the report is a detailed share price chart which plots discretionary trades by all the company's directo...

Alex Cogut
  • Alex Cogut

Coverage update

Given team and strategy changes, Alex Cogut is now assuming coverage of Achilles Therapeutics, Adaptimmune Therapeutics, Autolus, Calliditas, Cellectis, Galapagos, GenSight, Hansa Biopharma, Heidelberg Pharma, Immunocore, Innate Pharma, Sesorion and ValerioWe drop coverage of Celyad Oncology BioNte

Ingird Gafanhão ... (+2)
  • Ingird Gafanhão
  • Oscar Haffen Lamm

Conference updates: takeaways from ASCO and ISCT

We wrap up the past conference-filled weeks with a summary of the main takeaways from our coverage. From the International Society for Cell & Gene Therapy (ISCT) meeting, we point out i) Cellectis preclinical updates, and ii) a KOL dinner we hosted with Dr Bruce Levine discussing how to improve

Healthcare Team ... (+2)
  • Healthcare Team
  • Ingird Gafanhão

Transfer of coverage

from 1st June the cover of the following companies will be transferred to Ingrid GafanhaoADAPTIMMUNE THERAPEUTICSBIONTECHHEIDELBERG PHARMAIMMATICSIMMUNOCORE HOLDINGSINNATE PHARMAONXEOOSE IMMUNOTRANSGENE

Olga Smolentseva
  • Olga Smolentseva

Broad immune engagement by afami-cel presented at AACR

The company presented additional translational data at AACR, showing that afami-cel induced peripheral and tumoral innate and adaptive immune responses in patients with SyS and MRCLS (link). Notably, following afami-cel infusion, a greater tumoral immune infiltrate was demonstrated at the gene and

Olga Smolentseva
  • Olga Smolentseva

Settling GSK breakup

Adaptimmune announced additional details regarding the terms for the transfer of PRAME and NY-ESO-1 programs from GSK. Adaptimmune gained back the rights for lete-cel (NY-ESO-1-targeting TCR T therapy), next-generation NYESO CD8 and NYESO TGF, as well as preclinical PRAME-targeting programs followi

Olga Smolentseva
  • Olga Smolentseva

Pioneering TCR T cell therapy

We view Adaptimmune as one of the leaders in the TCR T space due to: i) initiated BLA submission for the lead asset, afami-cel, in synovial sarcoma, which could secure the first-ever approval for TCR-T therapy; ii) while afami-cel provided solid validation, the next generation program, ADP-A2M4CD8,

Alex Cogut ... (+6)
  • Alex Cogut
  • Ingird Gafanhão
  • Maria Vara
  • Olga Smolentseva
  • Oscar Haffen Lamm
  • Valliant Campagne

TCR therapeutics coming of age

With the opportunity to tap into the intracellular target universe and efficient TCR signalling, TCR-based therapies could reach beyond other immunotherapeutics. TCR-based therapeutics showed durable clinical responses in hard-to-treat solid tumours, a significant achievement and a sign of maturity

 PRESS RELEASE

Preclinical Proof-of-Concept Data Supporting Future Clinical Developme...

Preclinical Proof-of-Concept Data Supporting Future Clinical Development of Two New Cell Therapies Being Presented by Adaptimmune at ASGCT - New next-gen SPEAR T-cells (ADP-A2M4N7X19) designed to enhance depth and durability of clinical response demonstrated enhanced proliferation, survival, and recruitment of immune cells in vitro - - Engineered TILs (ADP-TILIL7) intended to improve clinical responses, produced levels of IL-7 shown to improve growth and survival in vitro - - The Company is planning to initiate a Phase 1 trial with ADP-A2M4N7X19 in multiple solid tumors and a single-cente...

 PRESS RELEASE

Adaptimmune Reports First Quarter Financial Results and Business Updat...

Adaptimmune Reports First Quarter Financial Results and Business Update - Pooled data from Cohort 1 of the SPEARHEAD-1 trial and the Phase 1 trial of afami-cel in patients with sarcoma to be presented as a poster at ASCO - - Preclinical data for two novel next-generation T-cell therapies to be presented in two posters at ASGCT - - Updated MAGE-A4 expression levels from the Company’s screening protocol presented at AACR confirm the potential of this target in a broad range of solid tumors - - Appointed Jo Brewer as Chief Scientific Officer - - Financial guidance confirmed: funded into ea...

 PRESS RELEASE

Adaptimmune Announces Appointment of Joanna Brewer as Chief Scientific...

Adaptimmune Announces Appointment of Joanna Brewer as Chief Scientific Officer PHILADELPHIA and OXFORDSHIRE, United Kingdom, May 04, 2022 (GLOBE NEWSWIRE) -- Adaptimmune Therapeutics plc (Nasdaq:ADAP), a leader in T-cell therapy to treat cancer, today announces the appointment of Dr. Joanna (Jo) Brewer as Chief Scientific Officer (CSO) effective immediately. “Jo Brewer is an exceptional scientific leader, and I am delighted that she has accepted the newly created CSO role, leading our ongoing scientific research, and developing future autologous and allogeneic therapies,” said Adrian Raw...

 PRESS RELEASE

Adaptimmune to Report Q1 2022 Financial Results and Business Updates o...

Adaptimmune to Report Q1 2022 Financial Results and Business Updates on Monday, May 9, 2022 PHILADELPHIA and OXFORDSHIRE, United Kingdom, April 28, 2022 (GLOBE NEWSWIRE) -- Adaptimmune Therapeutics plc (Nasdaq:ADAP), a leader in cell therapy to treat cancer, will report financial results and provide business updates for the first quarter ended March 31, 2022, before the US markets open on Monday, May 9, 2022. Following the announcement, the Company will host a live teleconference and webcast at 8:00 a.m. EDT (1:00 p.m. BST) that same day. The press release and the live webcast of the con...

 PRESS RELEASE

Adaptimmune Reports Fourth Quarter and Full Year 2021 Financial Result...

Adaptimmune Reports Fourth Quarter and Full Year 2021 Financial Results and Business Update - SPEARHEAD-1 met its primary endpoint - planning for afami-cel BLA submission in Q4 2022 for people with synovial sarcoma - - Moving to late-phase development with ADP-A2M4CD8: SURPASS-2 initiated in esophageal and EGJ cancers; initiating SURPASS-3 in ovarian cancer in 2022 - - Allogeneic platform on-track for planned IND submission in 2023 for first product targeting MAGE-A4 - - Started our strategic collaboration for allogeneic T-cell therapies with Genentech - $150 million upfront payment rece...

 PRESS RELEASE

Adaptimmune to Report Q4 and Full Year 2021 Financial Results and Busi...

Adaptimmune to Report Q4 and Full Year 2021 Financial Results and Business Updates on Monday, March 14, 2022 PHILADELPHIA and OXFORDSHIRE, United Kingdom, March 08, 2022 (GLOBE NEWSWIRE) -- Adaptimmune Therapeutics plc (Nasdaq:ADAP), a leader in cell therapy to treat cancer, will report financial results and provide business updates for the fourth quarter and year ended December 31, 2021, before the US markets open on Monday, March 14, 2022. Following the announcement, the Company will host a live teleconference and webcast at 8:30 a.m. EDT (12:30 p.m. GMT) that same day (details below). ...

ADAPTIMMUNE THERA sees an upgrade to Slightly Negative thanks to a bet...

The independent financial analyst theScreener just awarded an improved star rating to ADAPTIMMUNE THERA (US), active in the Biotechnology industry. As regards its fundamental valuation, the title receives an improved star rating and now shows 1 out of 4 possible stars. Given its market behaviour as risky, theScreener considers that these elements allowing slightly upgrading its general evaluation to Slightly Negative; the title, however, remains unattractive. As of the analysis date February 11,...

 PRESS RELEASE

Adaptimmune Announces Appointment of Cintia Piccina as Chief Commercia...

Adaptimmune Announces Appointment of Cintia Piccina as Chief Commercial Officer PHILADELPHIA and OXFORDSHIRE, United Kingdom, Jan. 26, 2022 (GLOBE NEWSWIRE) -- Adaptimmune Therapeutics plc (Nasdaq:ADAP), a leader in T-cell therapy to treat cancer, today announces the appointment of Cintia Piccina as Chief Commercial Officer effective January 31, 2022. “I am delighted to welcome Cintia to our leadership team. She brings extensive commercial experience, including in cell and gene therapy, that will be key as we prepare to submit our first BLA for afami-cel this year, and build our commerci...

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