reports
Investigational Epcoritamab (DuoBody® CD3xCD20) Combination Therapy De...
Investigational Epcoritamab (DuoBody® CD3xCD20) Combination Therapy Demonstrates High Response Rates in Clinical Trial of Patients With Relapsed or Refractory (R/R) Follicular Lymphoma (FL) Media ReleaseCOPENHAGEN, Denmark; December 7, 2024 Results show 96 percent overall response rate (ORR), 87 percent complete response (CR), and 80 percent 21-month progression-free survival (PFS) in patients with relapsed or refractory (R/R) follicular lymphoma (FL) following treatment with epcoritamab plus lenalidomide + rituximab (R2)Long-term follow-up results demonstrated strong and durable efficac...
Novel Combination of Pozelimab and Cemdisiran (Poze-Cemdi) Achieved Gr...
Novel Combination of Pozelimab and Cemdisiran (Poze-Cemdi) Achieved Greater Control of Intravascular Hemolysis in Patients with Paroxysmal Nocturnal Hemoglobinuria Compared to Ravulizumab Head-to-head exploratory cohort of a Phase 3 trial showed first-in-class poze-cemdi combination treatment helped patients achieve and maintain greater disease control, as measured by lactate dehydrogenase (LDH) levels, compared to standard-of-care ravulizumab Five patients receiving ravulizumab did not achieve meaningful LDH control compared to one patient receiving poze-cemdi; after switching to the comb...
Adaptive Biotechnologies Announces New Data at the 66th ASH Annual Mee...
Adaptive Biotechnologies Announces New Data at the 66th ASH Annual Meeting Highlighting Advances in MRD Testing with clonoSEQ® and Its Impact on Blood Cancer Treatment Decisions New data demonstrate the actionability of clonoSEQ for tailoring treatment decisions in patients with MCL, CLL, MM and ALL Studies show depth of response at 10-6 provides more accurate assessment of treatment responses SEATTLE, Dec. 07, 2024 (GLOBE NEWSWIRE) -- Adaptive Biotechnologies Corporation (Nasdaq: ADPT), a commercial stage biotechnology company that aims to translate the genetics of the adaptive imm...
HII Christens Virginia-Class Attack Submarine Arkansas (SSN 800)
HII Christens Virginia-Class Attack Submarine Arkansas (SSN 800) NEWPORT NEWS, Va., Dec. 07, 2024 (GLOBE NEWSWIRE) -- HII (NYSE: HII) today christened Virginia-class submarine Arkansas (SSN 800) at the company’s Newport News Shipbuilding (NNS) division. “Today we celebrate the mighty submarine Arkansas, and we honor bravery and impact: the heroes and heroic moments that shape our future and make us who we are,” NNS President Jennifer Boykin said. “As high school students, the Little Rock Nine exhibited courage, and showed the American people what determination and perseverance look like....
Galapagos Announces Encouraging New Results from Ongoing Phase 1/2 Stu...
Galapagos Announces Encouraging New Results from Ongoing Phase 1/2 Study of CD19 CAR T-Cell Therapy, GLPG5101, in Patients with Relapsed/Refractory Non-Hodgkin Lymphoma Data from the ongoing Phase 1/2 ATALANTA-1 study in a heavily pretreated R/R NHL patient population demonstrate high antitumor activity and an encouraging safety profile in all NHL subtypes studied.96% of patients received an infusion of fresh, fit, stem-like, early memory CD19 CAR T-cell therapy with a median vein-to-vein time of seven days, avoiding the need for cryopreservation and bridging therapy.These data reinforce th...
Galapagos kondigt bemoedigende nieuwe resultaten aan van de lopende fa...
Galapagos kondigt bemoedigende nieuwe resultaten aan van de lopende fase 1/2-studie van de CD19 CAR T-celtherapie GLPG5101 bij patiënten met recidief/refractair non-Hodgkin lymfoom De resultaten van de lopende fase 1/2 ATALANTA-1 studie in een zwaar voorbehandelde R/R NHL patiëntenpopulatie tonen hoge anti-tumoractiviteit en een bemoedigend veiligheidsprofiel in alle onderzochte NHL-subtypes.96% van de patiënten kregen een infusie met verse, fitte, stem-like, early memory CD19 CAR T-celtherapie met een mediane vein-to-vein tijd van zeven dagen, waardoor cryopreservatie en overbruggingsthera...
Park Ohio Holdings Corp: 2 directors
A director at Park Ohio Holdings Corp gave away 26,293 shares at 0.000USD and the significance rating of the trade was 11/100. Is that information sufficient for you to make an investment decision? This report gives details of those trades and adds context and analysis to them such that you can judge whether these trading decisions are ones worth following. Included in the report is a detailed share price chart which plots discretionary trades by all the company's directors over the last two y...
Marathon Petroleum Corp: 1 director
A director at Marathon Petroleum Corp bought 6,000 shares at 149.607USD and the significance rating of the trade was 100/100. Is that information sufficient for you to make an investment decision? This report gives details of those trades and adds context and analysis to them such that you can judge whether these trading decisions are ones worth following. Included in the report is a detailed share price chart which plots discretionary trades by all the company's directors over the last two ye...
Y-mAbs Presents SADA Platform Preclinical Data and Trial in Progress P...
Y-mAbs Presents SADA Platform Preclinical Data and Trial in Progress Posters at the 2024 American Society Hematology (ASH) Annual Meeting NEW YORK, Dec. 07, 2024 (GLOBE NEWSWIRE) -- Y-mAbs Therapeutics, Inc. (the “Company” or “Y-mAbs”) (Nasdaq: YMAB), a commercial-stage biopharmaceutical company focused on the development and commercialization of novel radioimmunotherapy and antibody-based therapeutic products for the treatment of cancer, today announced the presentation of CD38-SADA in Non-Hodgkin Lymphoma (NHL) preclinical data and trial in progress posters at the 66th American Society ...
Granite Ridge Resources Inc: 2 directors
Two Directors at Granite Ridge Resources Inc bought 42,000 shares at between 6.100USD and 6.240USD. The significance rating of the trade was 51/100. Is that information sufficient for you to make an investment decision? This report gives details of those trades and adds context and analysis to them such that you can judge whether these trading decisions are ones worth following. Included in the report is a detailed share price chart which plots discretionary trades by all the company's directo...
Graphjet Technology: 1 director
A director at Graphjet Technology sold 165,591 shares at 3.163USD and the significance rating of the trade was 62/100. Is that information sufficient for you to make an investment decision? This report gives details of those trades and adds context and analysis to them such that you can judge whether these trading decisions are ones worth following. Included in the report is a detailed share price chart which plots discretionary trades by all the company's directors over the last two years cle...
TAT Technologies Ltd: 2 directors
Two Directors at TAT Technologies Ltd sold 28,212 shares at between 22.190USD and 23.070USD. The significance rating of the trade was 81/100. Is that information sufficient for you to make an investment decision? This report gives details of those trades and adds context and analysis to them such that you can judge whether these trading decisions are ones worth following. Included in the report is a detailed share price chart which plots discretionary trades by all the company's directors over...
Finvolution Group: 1 director
A director at Finvolution Group sold 200,000 shares at 6.900USD and the significance rating of the trade was 100/100. Is that information sufficient for you to make an investment decision? This report gives details of those trades and adds context and analysis to them such that you can judge whether these trading decisions are ones worth following. Included in the report is a detailed share price chart which plots discretionary trades by all the company's directors over the last two years clea...
Shandong Shuangyi Technology Co Ltd: 1 director
A director at Shandong Shuangyi Technology Co Ltd sold 395,000 shares at 21.120CNY and the significance rating of the trade was 67/100. Is that information sufficient for you to make an investment decision? This report gives details of those trades and adds context and analysis to them such that you can judge whether these trading decisions are ones worth following. Included in the report is a detailed share price chart which plots discretionary trades by all the company's directors over the l...
Shenzhen Mindray Bio-Medical Electronics Co Ltd: 1 director
A director at Shenzhen Mindray Bio-Medical Electronics Co Ltd bought 3,900 shares at 255.000CNY and the significance rating of the trade was 52/100. Is that information sufficient for you to make an investment decision? This report gives details of those trades and adds context and analysis to them such that you can judge whether these trading decisions are ones worth following. Included in the report is a detailed share price chart which plots discretionary trades by all the company's directo...
Press Release: ASH: rilzabrutinib demonstrated significant patient ben...
Press Release: ASH: rilzabrutinib demonstrated significant patient benefit in the first positive phase 3 study of a BTK inhibitor in ITP ASH: rilzabrutinib demonstrated significant patient benefit in the first positive phase 3 study of a BTK inhibitor in ITP Pivotal phase 3 data show rapid and durable platelet response, reduced bleeding and need for rescue response, and improved physical fatigue and quality of life measures in patients with persistent or chronic ITPResults underscore the safety and efficacy of rilzabrutinib and its potential as the first BTK inhibitor in ITPRilzabrutinib i...
Communiqué de presse : ASH : le rilzabrutinib a apporté un bénéfice si...
Communiqué de presse : ASH : le rilzabrutinib a apporté un bénéfice significatif aux patients atteints de TPI dans le cadre de la première étude de phase III positive consacrée à un inhibiteur de la BTK ASH : le rilzabrutinib a apporté un bénéfice significatif aux patients atteints de TPI dans le cadre de la première étude de phase III positive consacrée à un inhibiteur de la BTK Les données pivots de phase III montrent une réponse plaquettaire rapide et durable, une diminution des saignements, du recours à un traitement d’urgence et de la fatigue physique, ainsi qu’une amélioration des...
Beam Therapeutics Announces New Data from BEACON Phase 1/2 Clinical Tr...
Beam Therapeutics Announces New Data from BEACON Phase 1/2 Clinical Trial of BEAM-101 in Sickle Cell Disease at American Society of Hematology (ASH) Annual Meeting All Seven Patients Treated with BEAM-101 Achieved Hemoglobin F (HbF) Induction of >60%, Hemoglobin S (HbS) Reduction to 60%, a decrease in hemoglobin S to
Agnico Eagle Mines Ltd: 1 director
A director at Agnico Eagle Mines Ltd sold 10,000 shares at 122.000CAD and the significance rating of the trade was 71/100. Is that information sufficient for you to make an investment decision? This report gives details of those trades and adds context and analysis to them such that you can judge whether these trading decisions are ones worth following. Included in the report is a detailed share price chart which plots discretionary trades by all the company's directors over the last two years...
Bragg Gaming Group Inc: 2 directors
Two Directors at Bragg Gaming Group Inc bought 39,300 shares at 3.150USD. The significance rating of the trade was 67/100. Is that information sufficient for you to make an investment decision? This report gives details of those trades and adds context and analysis to them such that you can judge whether these trading decisions are ones worth following. Included in the report is a detailed share price chart which plots discretionary trades by all the company's directors over the last two years...
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