Oncopeptides (Buy, TP: SEK135.00) - Strong data presented at ASH 2017
Oncopeptides reported stronger data than expected in its last update of the O-12-M1 phase II trial, with a PFS in RRMM patients of 5.7 months, compared with pomalidomide's PFS of c3.6 months in comparable patients. As the OCEAN trial (registration trial) is a head-to-head comparison with pomalidomide and has PFS as its primary end-point, the new data increases the likelihood of a successful phase III outcome in our view. We reiterate our BUY recommendation for Oncopeptides and have raised our target price to SEK135 (SEK82).Oncopeptides AB is a Sweden-based clinical development pharmaceutical company, which is primarily engaged in the healthcare industry. The Company focuses on research and development of cancer treatment solutions. The Company's product Ygalo is a peptidase potentiated alkylator, a type of cytotoxic drug that is targeted for use in the treatment of multiple myeloma. Ygalo is an alkylating agent that leverages the overrepresentation of peptidase enzymes in cancer cells to rise the concentration of active cancer fighting molecules in myeloma cells. Ygalo is intended for the treatment of patients with late-stage relapsed and refractory multiple myeloma. Ygalo is administered intravenously and is transported into cells where it is cleaved by peptidase enzymes, which impair transport of its active cancer-fighting agents out of the cell at the same time as driving more Ygalo into the cell.
DNB Markets is the investment banking arm of DNB Bank ASA and is focused primarily on the Nordic region, as well as internationally on niches such as global shipping, energy and related services, and seafood. DNB Markets offers services in FICC, Equities and Investment Banking advisory from offices in Oslo, Stockholm, London, Singapore and New York. Equity research coverage is offered on c250 Nordic companies. DNB was ranked no.2 in Extel Nordic Research 2017. The DNB Markets’ Credit and FICC Macro & FX Research teams are repeatedly highly rated by Prospera Nordic Institutional Investor Surveys.
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