Report
Patrik Ling
EUR 92.72 For Business Accounts Only

Targovax (Buy, TP: NOK19.00) - Promising data in mesothelioma

We believe the data Targovax reported yesterday on its phase I/II clinical trial in mesothelioma for ONCOS-102 is promising, and warrants the company proceeding to a larger trial. The plan is to combine ONCOS-102 with standard-of-care chemotherapy and a CPI in a c100 patient phase IIb trial. We believe the data presented yesterday justifies a higher LOA for the indication; as a result we have increased the LOA from 10% to 20% for the indication. Given the higher success rate, we have raised our target price to NOK19 (7), and reiterate our BUY recommendation.
Underlying
Targovax AS

Targovax ASA is a Norway-based company active within the healthcare sector. The Company is developing two complementary and targeted approaches in immuno-oncology: a peptide-based immunotherapy platform for patients with RAS-mutated cancers and a virus-based immunotherapy platform based on engineered oncolytic viruses armed with potent immune-stimulating transgenes for patients with solid tumors. The Company's candidate, TG01, is a peptide vaccine that targets mutations in the RAS genes that are associated with cancer, and it is in a phase II clinical trial in pancreatic cancer. The Company's other RAS targeting immunotherapy, TG02 is developed for colorectal cancer treatment. The Company's adenoviral candidate, ONCOS-102 is developed for the treatment of solid tumors, such as melanoma as well as ovarian and prostate cancer.

Provider
DnB Markets
DnB Markets

DNB Markets is the investment banking arm of DNB Bank ASA and is focused primarily on the Nordic region, as well as internationally on niches such as global shipping, energy and related services, and seafood. DNB Markets offers services in FICC, Equities and Investment Banking advisory from offices in Oslo, Stockholm, London, Singapore and New York. Equity research coverage is offered on c250 Nordic companies. DNB was ranked no.2 in Extel Nordic Research 2017. The DNB Markets’ Credit and FICC Macro & FX Research teams are repeatedly highly rated by Prospera Nordic Institutional Investor Surveys.

 

Analysts
Patrik Ling

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