Report

Oxford BioMedica (OXB): Ready for CTL019 approval

OXB is a specialist advanced therapy viral-vector biopharmaceutical company. It offers vector manufacturing and development services, whilst retaining proprietary drug candidates. OXB will also receive royalties on commercial products developed with its LentiVector® platform. In the six months to end June 2017, Novartis made considerable progress towards approval of CTL019, improving sentiment for OXB which supplies vector essential for its manufacture. Post-period, a new deal was signed with Novartis, with OXB potentially receiving >$100m over three years. The cash position @31st July was £22.1m.
Underlying
Oxford BioMedica PLC

Oxford BioMedica is a producer of gene and cell therapy in lentiviral vector and cell therapy research, development and production. Gene and cell therapy is the treatment of disease by the delivery of therapeutic deoxyribonucleic acid into a patient's cells. This can be achieved either in vivo (referred to as gene therapy) or ex vivo (referred to as cell therapy), the latter being where patients' cells are genetically modified cells outside the body before being re-infused. Co.'s products include: OXB-102, which targets Parkinson's disease; OXB-202, which targets corneal graft rejection; and OXB-302 (CAR-T 5T4), which targets targets a range of cancers.

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