Report
Karen Andersen
EUR 100.00 For Business Accounts Only

Slight Increase to Our Ionis FVE Following Solid 4Q and Pipeline Advancement

We have slightly raised our fair value estimate for Ionis to $52 per share from $49, after raising our Tegsedi pricing assumptions, adding explicit lines for Huntington's and ALS programs, but also pushing revenue from Waylivra (volanesorsen) back due to regulatory delays. Ionis' fourth-quarter and 2018 results were boosted significantly by the release of a valuation allowance related to taxes, as the firm is nearing profitability, but otherwise results were in line with our expectations, with o...
Underlying
Ionis Pharmaceuticals Inc.

Ionis Pharmaceuticals is engaged in discovering and developing RNA-targeted therapeutics. The company has two commercial medicines, SPINRAZA and TEGSEDI. SPINRAZA (nusinersen) injection for intrathecal use is a survival motor neuron-2, directed antisense oligonucleotide indicated for the treatment of spinal muscular atrophy in pediatric and adult patients. TEGSEDI (inotersen) injection is a Generation 2+ antisense medicine and an approved subcutaneous RNA-targeting medicine designed to treat people with polyneuropathy caused by hereditary transthyretin amyloidosis.

Provider
Morningstar
Morningstar

Morningstar, Inc. is a leading provider of independent investment research in North America, Europe, Australia, and Asia. The company offer an extensive line of products and services for individual investors, financial advisors, asset managers, and retirement plan providers and sponsors.

Morningstar provides data on approximately 530,000 investment offerings, including stocks, mutual funds, and similar vehicles, along with real-time global market data on more than 18 million equities, indexes, futures, options, commodities, and precious metals, in addition to foreign exchange and Treasury markets. Morningstar also offers investment management services through its investment advisory subsidiaries and had approximately $185 billion in assets under advisement and management as of June 30, 2016.

We have operations in 27 countries.

Analysts
Karen Andersen

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