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Valens Research

NBIX - Embedded Expectations Analysis - 2020 06 01

Neurocrine Biosciences, Inc. (NBIX:USA) currently trades below corporate averages relative to UAFRS-based (Uniform) earnings, with a 15.2x Uniform P/E. At these levels, the market has bearish expectations for the firm, but management is confident about their pipeline, IMBREZZA access, and their study registration

Specifically, management is confident the adaptive design of the CAH program studies allows them to optimize the dose and dosing schedule for crinecerfont, that IMBREZZA is the preferred VMAT2 inhibitor among providers, and that they must optimize levodopa before escalating the dosing of opicapone. In addition, they are confident they continue to focus on improving Tardive Dyskinesia (TD) diagnosis rates and that they have good clarity on their Parkinson's disease registration program
Underlying
Neurocrine Biosciences Inc.

Neurocrine Biosciences is a commercial-stage biopharmaceutical company focused on discovering and developing treatments for patients with neurological, endocrine and psychiatric disorders. The company is primarily focused on the commercialization of INGREZZA? (valbenazine) in the United States. The company's late-stage pipeline includes opicapone as an adjunctive therapy to levodopa/DOPA decarboxylase inhibitors in adult Parkinson's disease patients, elagolix for the treatment of heavy menstrual bleeding associated with uterine fibroids in women, valbenazine for the treatment of chorea in adult patients with Huntington's disease and NBIb-1817 (VY-AADC) for the treatment of Parkinson's disease patients.

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