1-800-FLOWERS.COM is a provider of gifts. The company's gifts include fresh flowers and a selection of plants, gift baskets, foods, confections, jewelry, candles, balloons and plush stuffed animals. The company's segments are: Consumer Floral, which includes the operations of the company's primary brand, 1-800-Flowers.com, FruitBouquets.com, Flowerama, Personalization Universe and Goodsey; Gourmet Foods and Gift Baskets, which includes the operations of Harry & David (which includes Wolferman's), Cheryl's (which includes Mrs. Beasley's), The Popcorn Factory, DesignPac and 1-800-Baskets (which includes Simply Chocolate); and BloomNet Wire Service, which includes the operations of BloomNet and Napco.

Adverum Biotechnologies is a clinical-stage gene therapy company targeting unmet medical need in ocular and rare diseases. The company develops gene therapy product candidates designed to provide durable efficacy by inducing sustained expression of a therapeutic protein. The company's main capabilities include clinical development, vector discovery, and in-house manufacturing expertise, specifically in scalable process development, assay development, and current Good Manufacturing Practices quality control. The company is conducting a clinical trial for its gene therapy candidate ADVM-022, AAV.7m8-aflibercept, for the treatment of wet age-related macular degeneration.

Agnico-Eagle Mines is a gold mining company with mining operations in Canada, Mexico and Finland. Co. earns a proportion of its revenues from the production and sale of gold in both dore bar and concentrate form. The remainder of revenue and cash flow is generated by the production and sale of byproduct metals. The revenue from byproduct metals is mainly generated by production at the LaRonde mine in Canada (silver, zinc, copper and lead) and the Pinos Altos mine in Mexico (silver).

Akebia Therapeutics is a biopharmaceutical company focused on the development and commercialization of therapeutics for people living with kidney disease. The company's portfolio includes: Vadadustat, which is an investigational, oral hypoxia-inducible factor prolyl hydroxylase inhibitor for two indications, anemia due to chronic kidney disease (CKD), in adult patients on dialysis, and anemia due to CKD in adult patients not on dialysis; and Auryxia? (ferric citrate), for the control of serum phosphorus levels in adult patients on dialysis, or the Hyperphosphatemia Indication, and the treatment of iron deficiency anemia (IDA) in adult patients not on dialysis, or the IDA Indication;

Alamos Gold is engaged in the exploration, mine development, and the mining and extraction of precious metals, primarily gold. Co.'s s primary asset is the Mulatos Mine and holds the mineral rights to the Salamandra group of concessions in the State of Sonora, Mexico, which includes several known satellite gold occurrences.

Atlas Air Worldwide Holdings is a holding company. Through its subsidiaries, the company is a provider of outsourced aircraft and aviation operating services in Africa, Asia, Australia, Europe, the Middle East, North America and South America. The company's business is organized into three operating segments: crew, maintenance and insurance (ACMI), which provides cargo aircraft outsourcing services to customers on an ACMI and crew, maintenance and insurance, but not the aircraft basis; cargo and passenger charter services, which provides planeload cargo and passenger aircraft to customers; and dry leasing aircraft and engines, which provides aircraft and engines to customers.

AudioCodes designs, develops and sells products and services for voice and data over packet networks. Voice over packet, or VoP, networks consist of key network elements such as software switches, application servers, Internet protocol (IP) phones, media gateways and session border controllers (SBC). Co.'s products primarily provide the media gateway and SBC element in the network, as well as voice over Internet protocol, or VoIP, end-points such as IP Phones and VoIP mobile clients. Multi-service business routers integrate media gateway functionality with data routing and network access. The media gateways connect legacy and IP networks.

Avantor is a global provider of mission critical products and services to customers in the biopharma, healthcare, education and government, and advanced technologies and applied materials industries. The company's comprehensive offerings, which include materials & consumables, equipment & instrumentation and services and specialty procurement, are relied upon by its customers, often on a recurring basis, because they are frequently specified into their research, development and production processes. The company operates in more than 30 countries and deliver an extensive portfolio of mission critical products, services and solutions.

AVEO Pharmaceuticals is a biopharmaceutical company. The company's product candidates include: tivozanib, its key candidate, a vascular endothelial growth factor receptor tyrosine kinase inhibitor which has been investigated in several tumor types, including renal cell, hepatocellular, colorectal and breast cancers; Ficlatuzumab, a hepatocyte growth factor inhibitory antibody, which is being tested for the treatment of squamous cell carcinoma of the head and neck, acute myeloid leukemia, and pancreatic cancer; AV-203, an anti-ErbB3 specific monoclonal antibody with high ErbB3 affinity; and AV-380, a humanized IgG1 inhibitory monoclonal antibody for the treatment or prevention of cachexia.

Bandwidth is a cloud-based communications platform-as-a-service (CPaaS) provider. The company's solutions include a range of software Application Programming Interfaces for voice and text functionality and its owned and managed, purpose-built Internet Protocol voice network. The company's operating segments include: CPaaS, which provides Voice, Messaging, 911 and Phone Numbers solutions through the company's proprietary CPaaS software application programming interfaces; and other, which consists of services provided such as SIP trunking, data resale, and a hosted Voice-over Internet Protocol and from traffic generated by other carriers, Short Message Service registration and other miscellaneous product lines.

Bio-Rad Laboratories is a manufacturer and distributor of its own life science research and clinical diagnostics products. The company has two primary segments: Life Science, which is engaged in the life sciences market and develops, manufactures and markets reagents, apparatus and laboratory instruments; and Clinical Diagnostics, which designs, manufactures, sells and supports test systems, informatics systems, test kits and quality controls that serve clinical laboratories in the diagnostics market. The company sells its products and services to a client base comprised of scientific research, healthcare, education and government customers.

Bio-Techne and its subsidiaries develop, manufacture and sell biotechnology life science reagents, instruments and services for the research and clinical diagnostic markets.Co.'s segments: Protein Sciences, which developes and manufactures purified proteins and reagent solutions, cytokines and growth factors, antibodies, immunoassays, biologically active small molecule compounds, tissue culture reagents and T-Cell activation technologies; and Diagnostics and Genomics, which develops and manufactures diagnostic products, including Food and Drug Administration-regulated controls, calibrators, blood gas and clinical chemistry controls and other reagents for Original Equipment Manufacturer.

Boston Beer Company is an alcoholic beverage company and a craft brewer. The company is engaged in the business of selling alcohol beverages throughout the United States and in selected international markets. The company's brands include Samuel Adams?, Twisted Tea?, Truly Hard Seltzer?, Wild Leaf? Hard Tea and Tura? Alcoholic Kombucha. The company produces alcohol beverages including malt beverages, hard cider and hard seltzer at the company-owned breweries and its cidery and under contract arrangements at other brewery locations. The company sells its products mainly in the United States, but also has markets in Canada, Europe, Israel, Australia, New Zealand, the Caribbean, the Pacific Rim, Mexico, and Central and South America.

Cameco and its subsidiaries are engaged in the exploration for and the development, mining, refining, conversion and fabrication of uranium for sale as fuel for generating electricity in nuclear power reactors in Canada and other countries. Co. has three reportable segments: uranium, which explores for, mines, mills, purchases, and sells uranium concentrate; fuel services, which refines, converts and fabricates uranium concentrate, and purchases and sells conversion services; and electricity, which generates and sells electricity through its 31.6% interest in the Bruce Power Limited Partnership, which operates four nuclear reactors and manages the overall site in southern Ontario.

CareDx together with its subsidiaries, is a medicine company focused on the discovery, development and commercialization of healthcare solutions for transplant patients and caregivers. The company provides testing services, products, and digital solutions along the pre- and post-transplant patient journey, and is a provider of genomics-based information for transplant patients. The company's testing services consist of AlloSure? Kidney, which is a donor-derived cell-free DNA solution for kidney transplant patients, and AlloMap? Heart, which is a gene expression solution for heart transplant patients.

Catalent is a holding company. Through its subsidiaries, the company is a provider of delivery technologies and development solutions for drugs, biologics and consumer health products. The company operates in four segments: Softgel Technologies, which provides formulation, development and manufacturing services for soft capsules; Biologics and Specialty Drug Delivery, which provides drug substance development and manufacturing; Oral Drug Delivery, which provides various formulation development and manufacturing technologies; and Clinical Supply Services, which provides manufacturing, packaging, storage, distribution, project management, and inventory management for drugs and biologics in clinical trials.

Chegg provides products and services that help students improve their outcomes throughout their educational journey. The company's offerings fall into two categories: Chegg Services, which encompasses all of its digital products and services such as Chegg Study, Chegg Writing, Chegg Tutors, Chegg Math Solver, and Other Services; and Required Materials, which primarily includes its print textbook and eTextbook offering. To deliver services to students, the company partners with a variety of third parties. The company sources print textbooks, eTextbooks, and supplemental materials directly or indirectly from publishers including Cengage Learning, Pearson, McGraw Hill, Sage Publications, and MacMillan.

Chemours is a provider of performance chemicals. The company has three reportable segments: Fluoroproducts, Chemical Solutions, and Titanium Technologies. The company's Fluoroproducts segment is a provider of fluoroproducts, including refrigerants and industrial fluoropolymer resins. The company's Chemical Solutions segment is a North American provider of industrial chemicals used in gold production, industrial, and consumer applications. The company's Titanium Technologies segment is a provider of titanium dioxide pigment, a white pigment used to deliver whiteness, brightness, opacity, and protection in a variety of applications.

Chiasma is a clinical-stage biopharmaceutical company focused on improving the lives of patients who face challenges related with their existing treatments for diseases. The company is evaluating oral octreotide capsules, conditionally trade-named MYCAPSSA, its sole Transient Permeability Enhancer platform-based clinical product candidate, in clinical trials in adult patients for the treatment of acromegaly to potentially support regulatory approval in the United States and European Union. The company is also conducting a clinical trial, referred to as MPOWERED, of oral octreotide capsules for the maintenance treatment of adult patients with acromegaly to support regulatory approval in the European Union.

ChromaDex is a provider of research and quality-control products and services to the natural products industry. Through its ingredients business segment, the company will continue to sell NIAGEN? in ingredient form to its strategic partners. In addition, the company will also continue to identify, acquire and commercialize other new proprietary ingredients and technologies. The company's products and services include: Consumer Products, which comprises TRU NIAGEN? branded dietary supplements; Ingredients, which includes Nicotinamide riboside NIAGEN? and Spirulina Extract Immulina?, a spirulina extract; and supplies a range of products necessary to conduct quality control of raw materials and consumer products.

Ciena is a networking systems, services and software company, providing solutions that enable a range of network operators to deploy and manage networks that deliver services to businesses and consumers. The company provides hardware, software and services that support the transport, switching, aggregation, service delivery and management of video, data and voice traffic on communications networks. The company's solutions are used by communications service providers, cable and multiservice operators, Web-scale providers, submarine network operators, governments, enterprises, research and education institutions and other network operators.

Compugen is a therapeutic discovery company based in Isreal. Co. is engaged in utilizing its broadly applicable predictive discovery infrastructure to discover novel drug targets and develop first-in-class therapeutics. Co. is advancing a therapeutic pipeline consisting mainly of early-stage immuno-oncology programs, aimed at harnessing the immune system to eradicate cancer. Co.'s pipeline is based on novel Compugen-discovered drug targets, primarily immune checkpoint candidates that are predicted to provide cancer immunotherapies addressing unmet cancer types and patient populations, both as monotherapy and in combination.

Coupa Software is a provider of business spend management (BSM) solutions. The company provides a cloud-based BSM platform that delivers a range of capabilities that would typically require the purchase and use of multiple disparate point applications. The company's main platform consists of procurement, invoicing, expense management and payments modules that form the transactional engine for managing a company's business spend. In addition, the company's platform provides supporting modules to help companies further manage their spend, including strategic sourcing, spend analysis, contract management, supplier management, and contingent workforce management.

Cytokinetics is a late-stage biopharmaceutical company focused on discovering, developing and commercializing muscle activators and muscle inhibitors as treatments for debilitating diseases in which muscle performance is compromised and/or declining. The company's clinical-stage drug candidates are: omecamtiv mecarbil, a cardiac myosin activator for the treatment of heart failure, AMG 594, a cardiac troponin activator, reldesemtiv, a skeletal muscle troponin activator for the treatments of spinal muscular atrophy and amyotrophic lateral sclerosis, and CK-3773274, a cardiac myosin inhibitor which is designed to reduce the hypercontractility that is associated with hypertrophic cardiomyopathy.

CytomX Therapeutics is clinical-stage, oncology-focused biopharmaceutical company with a class of investigational antibody therapeutics based on its Probody? technology platform the treatment of cancer. The company uses its platform to create proprietary cancer immunotherapies against clinically-validated targets. The company's two programs, CX-072, a wholly owned PD-L1-targeting Probody therapeutic and CX-2009, wholly owned CD166-targeting Probody drug conjugate. Both CX-072 and CX-2009 are part of PROCLAIM (Probody Clinical Assessment in Man), an international umbrella clinical trial program that provides clinical trial sites with access to the company's novel therapies under one central protocol.

DexCom is a medical device company primarily focused on the design, development and commercialization of continuous glucose monitoring systems for use by people with diabetes and by healthcare providers. The company's products include: DecCom G6?, which allows the company's transmitter to run an algorithm to generate a glucose value and to communicate to a patient's mobile device; DexCom G4? PLATINUM, which is used to adjust therapy and to educate and motivate patients to modify their behavior after viewing the effects that specific foods, exercise, stress and medications have on their glucose levels; and DexCom Share?, which transmits glucose information to the mobile devices of designated recipients.

DocuSign provides e-signature solution as the main part of its cloud software suite for automating the agreement process. The company calls its suite the DocuSign Agreement Cloud. The DocuSign Agreement Cloud is designed to allow companies of various sizes and across various industries to make agreement, approval process, or transaction digital, from practically any device, from almost anywhere in the world.

eBay is a global commerce provider, which includes its Marketplace, StubHub and Classifieds platforms. The company's Marketplace platforms include its online marketplace located at www.ebay.com, its localized counterparts and the eBay suite of mobile apps. The company's StubHub platforms include its online ticket platform located at www.stubhub.com, its localized counterparts and the StubHub mobile apps. These platforms connect fans with their favorite sporting events, shows and artists and enable them to buy and sell tickets whenever and wherever they want. The company's Classifieds platforms include a collection of brands such as mobile.de, Kijiji, Gumtree, Marktplaats, eBay Kleinanzeigen and others.

Eland Oil & Gas is an independent oil and gas company focused on production and development in West Africa, particularly the Niger Delta region of Nigeria. Co.'s primary assets are the Oil Mining Lease 40 (OML 40) licence and the Ubima field, both onshore Nigeria. In 2016, Co.'s OML 40 licence asset had gross proved and probable oil reserves of 83.2 million barrels and its Ubima field asset had gross proved and probable oil reserves of 2.4 million barrels.

Electromed develops, manufactures, markets and sells products that provide airway clearance therapy, including the SmartVest? Airway Clearance System (SmartVest System) and related products, to patients with compromised pulmonary function. The SmartVest System is available in two models, SV2100 and SQL?. The SmartVest SQL System consists of an inflatable therapy garment, a programmable air pulse generator and a patented single-hose that delivers air pulses from the generator to the garment. The company also markets the Single Patient Use SmartVest? and SmartVest Wrap? to health care providers in the acute care setting.

Electronic Arts develops, markets, publishes and distributes games, content and services that can be played and watched on a variety of platforms, including game consoles, personal computers, and mobile phones. The company markets and sells its games and services through digital distribution channels and through retail channels. Digitally, the company's console games and services can be purchased through third-party storefronts. In its games and services, the company utilizes brands that it either wholly own or license from others. The company develops and publishes games and services across genres. Within and alongside its games, the company provides live services, including in-game purchases, downloadable content, and esports.

Emergent BioSolutions is a life sciences company. The company is focused on preparedness and response products and solutions that address the following categories: Chemical, Biological, Radiological, Nuclear and Explosives; emerging infectious diseases; travel health; emerging health crises; acute/emergency care; and contract development and manufacturing. The company also has a development pipeline consisting of a mix of both pre-clinical and clinical-stage product candidates, including Trobigard? a combination drug-device auto injector product candidate. In addition, the company has a fully integrated molecule-to-market biologics CDMO business offerings (development services, drug substance and drug product).

Etsy provides sellers a marketplace with buyers along with a range of seller tools and services that are specifically designed to help its creative entrepreneurs generate more sales and scale their businesses. The company's platform includes the Etsy and Reverb Holdings, Inc. (Reverb) online marketplaces, its seller tools and services, its engaged sellers and buyers, and its technology. The company's primary marketplace, Etsy.com, is where buyers come to discover a selection of goods that are hard to find elsewhere. Reverb, the company's subsidiary, operates as a standalone marketplace. This two-sided marketplace connects buyers and sellers of new, used, and vintage musical gear from all over the world.

F5 Networks is a provider of multi-cloud application services, which enable its customers to develop, deploy, operate, secure, and govern applications in any architecture, from on-premises to the public cloud. The company's application services are available as cloud-based, software-as-a-service, and software-only solutions supported for multi-cloud environments. In connection with its solutions, the company provides a range of services, including consulting, training, installation, maintenance, and other technical support services. The company's products and solutions include hardware platforms, software and software-as-a-service platforms, cloud-based managed services, and service provider solutions.

Halozyme Therapeutics is a biopharma technology platform company that provides solutions to improve patient experience and outcomes. The company's approved product and its collaborators' approved products and product candidates are based on rHuPH20, its patented recombinant human hyaluronidase enzyme. The company refers to the application of rHuPH20 to facilitate the delivery of other drugs or fluids as its ENHANZE? Drug Delivery Technology (ENHANZE). The company licenses the ENHANZE technology to form collaborations with biopharmaceutical companies that develop or market drugs requiring or benefiting from injection via the subcutaneous route of administration.

Incyte is a biopharmaceutical company focused on the discovery, development and commercialization of therapeutics. JAKAFI (ruxolitinib) has been approved for the treatment of patients with intermediate or high-risk myelofibrosis, for the treatment of patients with polycythemia vera, and for the treatment of steroid-refractory acute graft-versus-host disease in adult and pediatric patients 12 years and older. The company has also obtained a license to develop and commercialize ICLUSIG (ponatinib) in Europe and other select countries. In the European Union, ICLUSIG is approved for the treatment of adult patients with chronic phase, accelerated phase or blast phase chronic myeloid leukemia.

iRhythm Technologies is a digital healthcare company redefining the way cardiac arrhythmias are clinically diagnosed by combining its wearable biosensing technology with cloud-based data analytics and capabilities. The company has developed a long-term continuous ambulatory cardiac monitoring platform known as the Zio service that provides continuous ambulatory cardiac monitoring through Zio XT monitor and Zio AT monitor. While wearing either the Zio XT or Zio AT monitor, patients can mark when symptoms occur by pressing a trigger button on the device and separately recording contextual data like activities and circumstances in a written symptom diary or digitally via the myZio application.

Kinross Gold is engaged in the mining and processing of gold and, as a by-product, silver ore and the exploration for, and the acquisition of, gold bearing properties in the Americas, the Russian Federation, West Africa and worldwide. As of Dec 31 2013, Co.'s proven mineral reserves for gold and silver were 1,122 ounces and 1,179 ounces respectively.7,883 7,883 7,883

Kinsale Capital Group is an insurance holding company. The company focuses on the excess and surplus lines (E&S) market in the U.S., where it can use its underwriting capability to write coverages for hard-to-place small business risks and personal lines risks. The company's segment, Excess and Surplus Lines Insurance segment provides property and casualty insurance products through the E&S market. The company's commercial lines offerings include construction, small business, excess casualty, energy, product liability, general casualty, allied health, professional liability, life sciences, commercial property, management liability, health care, environmental, inland marine, public entity, and commercial insurance.

Lattice Semiconductor develops semiconductor technologies. The company delivers two types of semiconductor devices to its customers: Field Programmable Gate Arrays (FPGAs), and Video Connectivity Application Specific Standard Products (ASSPs). The company's FPGAs offerings consist of five product family lines: the ECP families, the MachXO families, iCE40 families, CrossLink, and Programmable Mixed Signal devices. The company's Video Connectivity ASSPs perform various functions, including ensuring interoperability, improving picture quality, converting between resolutions, and transmitting / receiving content without the need for additional components.

Luminex develops, manufactures and sells biological testing technologies and products with applications in the life sciences industries, including diagnostics, pharmaceutical and research. The company delivers its products to various market segments, including multiplexing, reduction of labor and ability to test for proteins and nucleic acids. The company's products include: instruments, which include Luminex? 100/200?, FLEXMAP? 3D, MAGPIX?, ARIES?, and ARIES? M1; consumables, which include MicroPlex? Microspheres, MagPlex? Microspheres, and xTAG? Microspheres; software, which includes xPONENT?, TDAS?, SYNCT?, and IDEAS?; and clinical diagnostic assay product families, which include ARIES? Cassettes.

MACOM Technology Solutions Holdings is a holding company. Through its subsidiaries, the company is a provider of analog semiconductor solutions that enable internet applications, the cloud connected apps economy and the networked battlefield across the radio frequency (RF), microwave, millimeterwave and lightwave spectrum. The company's primary markets are: Telecom, which includes carrier infrastructure like long-haul/metro, 5G and fiber-to-the-X/passive optical network; Data Centers, enabled by a portfolio of analog ICs and photonic components for high speed optical module consumers; and Industrial and Defense, which includes military and commercial radar, RF jammers, electronic and countermeasures.

MAG Silver is an exploration company conducting work on mineral properties it has staked or acquired by way of option agreement, principally in Mexico. Co. has not yet determined whether the properties on which it is conducting exploration contain any ore reserves that are economically recoverable. The recoverability of these amounts is dependent upon the existence of economically recoverable reserves, Co.'s ability to obtain the necessary financing to complete the development of the interests, and future profitable production, or alternatively, upon Co.’s ability to dispose of its interests on a profitable basis.

MarketAxess Holdings operates an electronic trading platform that enables fixed-income market participants to trade corporate bonds and other types of fixed-income instruments using its patented technology. Through its Open Trading? protocols, the company executes trades in certain bond between and among institutional investor and broker-dealer clients. The company also provides trading-related products and services, including: Composite+ pricing and other market data products to assist clients with trading decisions; auto-execution and other execution services for clients requiring specialized workflow solutions; connectivity solutions that facilitate straight-through processing; and technology services.

Marten Transport is a temperature-sensitive truckload carrier. The company has four segments: Truckload, which provides regional short-haul and medium-to-long-haul full-load transportation services; Dedicated, which provides customized transportation solutions using temperature-controlled trailers, dry vans and other equipment; Intermodal, which transports customers' freight using its temperature-controlled trailers on railroad flatcars for portions of trips, with the balance of the trips using its tractors or, to a lesser extent, contracted carriers; and Brokerage, which arranges for third-party carriers to transport freight for its customers in temperature-controlled trailers and dry vans.

Masimo is a medical technology company that develops, manufactures, and markets a variety of noninvasive monitoring technologies. The company provides its products to hospitals, emergency medical service providers, long-term care facilities, physician offices, veterinarians and consumers. The company's main business is Measure-through Motion and Low Perfusion? pulse oximetry monitoring, known as Masimo Signal Extraction Technology? pulse oximetry. The company's products offerings also includes noninvasive monitoring of blood constituents with an optical signature, optical organ oximetry monitoring, electrical brain function monitoring, acoustic respiration monitoring and exhaled gas monitoring.

Minerva Neurosciences is a clinical-stage biopharmaceutical company focused on the development and commercialization of a portfolio of products candidates to treat patients suffering from central nervous system diseases. The company's product portfolio and potential indications include: roluperidone (also known as MIN-101) for the treatment of negative symptoms in patients with schizophrenia; seltorexant (also known as MIN-202 or JNJ-42847922), which the company is co-developing with Janssen Pharmaceutica NV, for the treatment of insomnia disorder and adjunctive treatment of Major Depressive Disorder (aMDD); MIN-117 for the treatment of MDD; and MIN-301 for the treatment of Parkinson's disease.

Molina Healthcare is a holding company. Through its subsidiaries, the company provides managed healthcare services under the Medicaid and Medicare programs, and through the state insurance marketplaces. The company has two segments: Health Plans and Other. The company's health plans are operated by its respective wholly owned subsidiaries in those states, each of which is licensed as a health maintenance organization. The company's business includes: Medicaid, which provides health care and long-term care services and support to low-income Americans; and Medicare, which provides eligible persons age 65 and over and some disabled persons with a variety of hospital, medical insurance, and prescription drug benefits.

Momenta Pharmaceuticals is a biotechnology company focused on the discovery and development of biologic therapies for the treatment of rare immune-mediated diseases. The company's programs include: M281, which is a fully-human anti-neonatal Fc receptor (FcRn), aglycosylated immunoglobulin G (IgG1), monoclonal antibody, designed to reduce circulating human immunoglobulin G (IgG) antibodies by completely blocking endogenous IgG recycling via FcRn; M230, which is a recombinant trivalent human IgG1 Fc multimer; and M254, which is a hyper-sialylated immunoglobulin designed as a high potency alternative to IVIg, a therapeutic drug product that contains pooled, IgG antibodies purified from blood plasma.

Monolithic Power Systems is a fabless semiconductor company. The company designs, develops and markets power solutions for systems found in consumer, computing and storage, automotive, industrial, communications and consumer applications. The company's primary product families include the following: Direct Current (DC) to DC products, which are used to convert and control voltages within a range of electronic systems such as portable electronic devices, wireless Local Area Network access points, computers, and monitors, automobiles and medical equipment; and Lighting Control Products, which include lighting control integrated circuits that are used in backlighting and general illumination products.

MSCI is a provider of decision support tools and services for the global investment community. The company's segments are: Index, in which Clients use the company's indexes in various areas of the investment process, including index-linked product creation; Analytics, which provides risk management, performance attribution and portfolio management content, applications and services; Environmental, Social and Governance (ESG), which helps institutional investors understand how ESG considerations can impact the long-term risk and reward of their portfolio and individual security-level investments; and Real Estate, which includes research, reporting, market data and benchmarking offerings.

Newmont is primarily a gold producer with operations and/or assets in the United States, Canada, Mexico, Dominican Republic, Peru, Suriname, Argentina, Chile, Australia and Ghana. The company is also engaged in the production of copper, silver, lead and zinc. The company's operations are organized in five geographic regions; North America, South America, Australia, Africa and Nevada.

Nucor manufactures steel and steel products. The company's operations include international trading and sales companies that buy and sell steel and steel products. The company's segments are: steel mills, which produces sheet steel, plate steel, structural steel, and bar steel; steel products, which produces hollow structural section steel tubing, electrical conduit, steel joists and joist girders, steel deck, cold finished steel, steel fasteners, metal building systems, and wire and wire mesh; and raw materials, which produces direct reduced iron (DRI), brokers ferrous and nonferrous metals, pig iron, hot briquetted iron and DRI, supplies ferro-alloys, and processes ferrous and nonferrous scrap metal.

Old Dominion Freight Line is a less-than-truckload (LTL) motor carrier providing regional, inter-regional and national LTL services, which include expedited transportation. In addition to the company's primary LTL services, the company provides a range of services including container drayage, truckload brokerage and supply chain consulting. The company also provides access to its systems through multiple gateways that provide its customers and employees flexibility and access to information. The company employs vehicle safety systems, on-board and hand-held computer systems, freight handling systems and logistics technology to reduce costs and transit times.

Papa John's International operates and franchises pizza delivery and carryout restaurants and, in certain international markets, dine-in and delivery restaurants. The company has four reportable segments: domestic the company-owned restaurants, which engages in retail sales of pizza and side items; North America commissaries, which includes the operations of the company's regional dough production and product distribution centers; North America franchising, which includes the company's franchise sales and support activities; and international operations, which includes the distribution sales to franchised Papa John's restaurants in the United Kingdom and its franchise sales and support activities.

PayPal Holdings is a technology platform and digital payments company that enables digital and mobile payments on behalf of consumers and merchants worldwide. The company's combined payment solutions include its PayPal, PayPal Credit, Braintree, Venmo, Xoom and iZettle products and services. PayPal's payment solutions enable the company's customers to send and receive payments. PayPal helps merchants and consumers connect, transact, and complete payments, whether they are online, on a mobile device, in an app, or in person. The company provides proprietary payment solutions accepted by merchants that enable the completion of payments on the company's Payments Platform on behalf of its customers.

Proto Labs is a digital manufacturer of custom prototypes and production parts. The company's primary manufacturing product lines include Injection Molding, which uses three-dimensional (3D) computer-aided design-to-computer numerical control (CNC) machining technology for the automated design and manufacture of molds; CNC Machining, which uses commercially available CNC machines to provide milling and turning; 3D Printing, which includes stereolithography, selective laser sintering, direct metal laser sintering, Multi Jet Fusion and PolyJet processes; and Sheet Metal, which includes e-commerce-enabled custom sheet metal parts, providing customers with prototype and low-volume production parts.

Qorvo is a holding company. Through its subsidiaries, the company designs, develops, manufactures and markets its products to U.S. and international original equipment manufacturers and original design manufacturers in two operating segments: Mobile Products, which is a supplier of cellular radio frequency (RF) and Wi-Fi solutions for mobile devices, including smartphones, wearables, laptops, tablets and cellular-based applications for the Internet of Things (IoT); and Infrastructure and Defense Products, which is a supplier of RF and system-on-a-chip solutions for cellular base stations and other wireless communications infrastructure, defense, smart home, automotive and other IoT applications.

RealPage is a provider of software and data analytics to the real estate industry. The company's platform consists of four categories of solutions: Property Management, which manages primary property management business processes, including leasing, accounting, budgeting, purchasing, facilities management, and support and advisory services; Leasing and Marketing, which manages primary leasing and marketing processes; Resident Services, which provides a platform to improve the transactional of prospects and renters and improve a property's reputation; and Asset Optimization, which provides analytics-based decision support for investment performance throughout the phases of real estate investment.

Retractable Technologies is engaged in the manufacturing and marketing of safety medical products (mainly syringes) for the healthcare industry. The company's VanishPoint? safety products include tuberculin, insulin, and allergy antigen VanishPoint? syringes; VanishPoint? syringes; and the VanishPoint? autodisable syringe. The company also sells the VanishPoint? IV catheter; the VanishPoint? blood collection tube holder; and the VanishPoint? blood collection set. The Patient Safe? syringe protects patients by reducing the risk of bloodstream infections associated with catheter hub contamination. The company's Patient Safe? products include 3mL, 5mL, 10mL, 20mL, 30mL, 60mL syringes and the Patient Safe? Luer cap.

Rockwell Automation is a provider of industrial automation and digital transformation. The company's segments include: Architecture and Software, which contains automation and information platforms, including hardware and software; and Control Products and Solutions, which combines motor control and industrial control products, other solutions and a portfolio of lifecycle services. The company's automation platform products include programmable automation controllers, design, networking products, sensing devices, machine safety devices, motion control products, and independent cart technology products. The company's information platform includes manufacturing execution system software and analytics software.

Royal Gold acquires and manages precious metal streams, royalties and similar interests. The company acquires existing stream and royalty interests or finances projects that are in production or in the development stage in exchange for stream or royalty interests. A metal stream is a purchase agreement that provides, in exchange for an upfront deposit payment, the right to purchase all or a portion of one or more metals produced from a mine, at a price determined for the life of the transaction by the purchase agreement. Royalties are non-operating interests in mining projects that provide the right to a portion of revenue or metals produced from the project after deducting specified costs, if any.

S&P Global is a provider of transparent and independent ratings, benchmarks, analytics and data to the capital and commodity markets worldwide. The company's segments include: S&P Global Ratings, which provides credit ratings, research and analytics; S&P Global Market Intelligence, which provides multi-asset-class data, research and analytical capabilities that integrate cross-asset analytics and desktop services; S&P Global Platts, which provides information and benchmark prices for the commodity and energy markets; and S&P Dow Jones Indices, which provides a variety of valuation and index benchmarks for investment advisors, wealth managers and institutional investors.

SciPlay is a developer and publisher of digital games on mobile and web platforms. The company offers seven core games, including social casino games Jackpot Party Casino, Gold Fish Casino, Hot Shot Casino and Quick Hit Slots, and casual games MONOPOLY Slots, Bingo Showdown and 88 Fortunes Slots. The company's social casino games include slots-style play and table games-style game play, while its casual games blend slots-style or bingo game play with adventure game features. The company's games are offered and played across multiple platforms, including Apple, Google, Facebook and Amazon. In addition, the company's content library includes recognizable, real-world slot and table games content from Scientific Games.

Scotts Miracle-Gro is a manufacturer and marketer of consumer lawn and garden products in North America. The company's segments are: United States Consumer, which consists of the company's consumer lawn and garden business located in United States; Hawthorne, which consists of the company's indoor, urban and hydroponic gardening business; and Other, which consists of the company's consumer lawn and garden business in geographies other than the United States and the company's product sales to nurseries, greenhouses and other customers. The company manufactures, markets and sells lawn and garden products in the following categories: lawn care, gardening and landscape, hydroponics, and controls.

ServiceNow provides enterprise cloud computing services that define, structure, manage and automate digital workflows for global enterprises. The company markets its services to enterprises in a variety of industries, including consumer products, education, financial services, government, health care, information technology (IT) services and technology. The company sells its subscription services through direct sales and, to a lesser extent, through indirect channel sales. The company also provides a portfolio of personnel and other services, both directly and through its network of partners. The company's products include IT service management, IT operations management, IT business management, and security operations.

Shopify provides a cloud-based commerce platform designed for small and medium-sized businesses. Merchants use its software to run their business across all of their sales channels, including web, tablet and mobile storefronts, social media storefronts, and brick-and-mortar and pop-up shops. Co. provides a platform for merchants to create an omni-channel experience that helps showcase the merchant's brand and grow its business. Co.'s platform provides merchants with a single view of their business and customers across all of their sales channels and enables them to manage products and inventory, process orders and payments, build customer relationships and leverage analytics and reporting.

SIGA Technologies is a commercial-stage pharmaceutical company focused on the health security market. Health security comprises countermeasures for biological, chemical, radiological and nuclear attacks, vaccines and therapies for emerging infectious diseases, and health preparedness. The company's primary product is an oral formulation of TPOXX?, an antiviral drug for the treatment of human smallpox disease caused by variola virus. The United States Food and Drug Administration has approved oral TPOXX? for the treatment of smallpox.

Skyworks Solutions is a provider of analog semiconductors that connect people, places, and things, spanning a number of applications within the aerospace, automotive, broadband, cellular infrastructure, connected home, industrial, medical, military, smartphone, tablet and wearable markets. The company's product portfolio consists of various solutions, including: amplifiers, antenna tuners, attenuators, circulators/isolators, wireless analog system on chip, direct current (DC)/DC converters, demodulators, detectors, diodes, directional couplers, diversity receive modules, filters, front-end modules, hybrid, light emitting diode drivers, low noise amplifiers, mixers, and modulators.

Smartsheet is a cloud-based platform for work execution, enabling teams and organizations to plan, capture, manage, automate, and report on work at scale. Customers access their accounts online via a web-based interface or a mobile application. Some customers also purchase the company's other services, which primarily consist of consulting and training services. The company's products are comprised of: Smartdashboards, Smartportals, Smartcards, Smartgrids, Smartprojects, Smartcalendars, Smartforms, Smartautomation, Smartintegrations, Connectors, Control Center, Accelerators, Dynamic View, and Data Uploader.

Spero Therapeutics is a multi-asset, clinical-stage biopharmaceutical company focused on identifying, developing and commercializing novel treatments for multi-drug resistant (MDR), bacterial infections. The company's product candidate, SPR994 (tebipenem pivoxil hydrobromide), is designed to be oral carbapenem-class antibiotic for use in adults to treat MDR Gram-negative infections. The company also has a platform technology known as its Potentiator Platform, which includes two intravenous-administered agents, SPR206 and SPR741, that are active either alone or in combination with other standard of care agents and are designed to treat MDR Gram-negative bacteria in the hospital.

Sprouts Farmers Market operates as a healthy grocery store. The company categorizes the varieties of products it sells as perishable and non-perishable. Perishable product categories include produce, meat, seafood, deli, bakery, floral and dairy and dairy alternatives. Non-perishable product categories include grocery, vitamins and supplements, bulk items, frozen foods, beer and wine, and natural health and body care. The company's stores include the following departments: packaged groceries, meat and seafood, deli, vitamins and supplements, dairy and dairy alternatives, bulk items, baked goods, frozen foods, natural health and body care, and beer and wine.

SSR Mining is engaged in the acquisition, exploration, development and operation of silver-dominant resource properties located in the Americas. Co.'s strategic focus is to optimize the production of silver from its Pirquitas mine in Argentina, and to advance other principal development and exploration projects including San Luis in Peru, Diablillos in Argentina, and Pitarrilla and San Agustin in Mexico. In addition to its principal projects, Co. holds a geologically-diverse portfolio of other predominantly silver projects in various stages of exploration.

Syndax Pharmaceuticals is a clinical-stage biopharmaceutical company developing a pipeline of cancer therapies. The company's primary product candidate, entinostat is a once-weekly, oral, small molecule, Class I HDAC inhibitor, which is being evaluated in the Phase 3 E2112 registrational clinical trial in combination with exemestane for hormone receptor positive, human epidermal growth factor receptor 2 negative, breast cancer, an indication for which entinostat has been granted therapy designation from the United States Food and Drug Administration. SNDX-5613, the company's clinical-stage product candidate, is a small molecule inhibitor of the interaction of menin with the mixed lineage leukemia protein.

Tractor Supply is a rural lifestyle retailer. The company is focused on supplying the needs of recreational farmers, ranchers and all those who enjoy living the rural lifestyle, as well as tradesmen and small businesses. The company operates retail stores under the names Tractor Supply Company, Del's Feed & Farm Supply, and Petsense and operates websites under the names TractorSupply.com and Petsense.com. The company's selection of merchandise is comprised of the following main product categories: equine, livestock, pet, and small animal products; hardware, truck, towing, and tool products; seasonal products; work/recreational clothing and footwear; and maintenance products for agricultural and rural use.

Trex Company is a manufacturer of composite decking and railing products, which are marketed under the brand name Trex?. In addition, the company is a national provider of custom-engineered railing and staging, systems for the commercial and multi-family market, including sports stadiums and performing arts venues. The company operates in two reportable segments: Trex Residential Products, which provides a set of product offerings in the decking, railing, fencing, steel deck framing, and outdoor lighting categories; and Trex Commercial Products, which designs and engineers custom railing solutions, which are used in collegiate sports facilities, standardized architectural and aluminum railing systems.

United States Steel is a steel producer of flat-rolled and tubular products with production operations in the United States and Europe. The company is also engaged in railroad services and real estate operations. The company's segments are: North American Flat-Rolled, which produces slabs, strip mill plates, sheets and tin mill products; U. S. Steel Europe, which produces and sells slabs, strip mill plate, sheet, tin mill products and spiral welded pipe, as well as heating radiators and refractory ceramic materials; and Tubular Products, which produces and sells electric resistance welded steel casing and tubing (known as oil country tubular goods), and standard and line pipe and mechanical tubing.

Vapotherm is a medical technology company focused on the development and commercialization of its proprietary Hi-VNI Technology products that are used to treat patients of all ages suffering from respiratory distress. The company's Hi-VNI Technology delivers non-invasive ventilatory support by providing heated, humidified and oxygenated air at a high velocity to patients through a small-bore nasal interface. The company provides four versions of its Precision Flow systems: Precision Flow Hi-VNI, Precision Flow Plus, Precision Flow Classic and Precision Flow Heliox. The company's companion products include: Vapotherm Transfer Unit 2.0, the Q50 compressor, the aerosol aeroneb adaptor, and a tracheostomy adaptor.

Veeva Systems provides industry cloud solutions for the life sciences industry. Veeva Commercial Cloud is a suite of multichannel customer relationship management applications, a commercial data warehouse, territory allocation and alignment applications, master data management applications and customer reference and data and services. Veeva Vault is the company's suite of cloud-based, enterprise content management applications that address the content management requirements for the company's customers'commercial functions, including medical and sales and marketing, and key research and development functions, including clinical, regulatory, quality, and, when available, safety.

Verisec AB is a Sweden-based company which provides security solutions for banking, government and business customers.

Wayfair is a holding company. Through its e-commerce business model, the company provides customers with browsing, merchandising and product discovery for products from various suppliers. The company has online selections of furniture, decor, decorative accents, housewares, seasonal decor and other home goods. The company's mobile app also provides customers a way to shop for their home from their home using its View in Room 3D augmented reality tool. The company's sites include: Wayfair, Joss & Main, AllModern, Birch Lane, and Perigold. Wayfair is the only one of the company's sites that also operates internationally, operating as Wayfair.ca in Canada, Wayfair.co.uk in the U.K. and Wayfair.de in Germany.

Weis Markets is engaged in the retail sale of food in Pennsylvania. The company's retail food stores sell groceries, dairy products, frozen foods, meats, seafood, fresh produce, floral, pharmacy services, deli products, prepared foods, bakery products, beer and wine, fuel and general merchandise items, such as health and beauty care and household products. The store product selection includes national, local and private brands including natural, gluten-free and organic varieties. All retail food store locations operate as conventional supermarkets. The company utilizes a loyalty marketing program, Weis Club Preferred Shopper, which enable customers to receive discounts, promotions and fuel rewards.

Werner Enterprises is a transportation and logistics company engaged primarily in transporting truckload shipments of general commodities in both interstate and intrastate commerce. The company has two reportable segments: Truckload Transportation Services, which includes the medium-to-long-haul van fleet that transports a variety of consumer nondurable products and other commodities in truckload quantities over irregular routes using dry van trailers, the expedited fleet that provides truckload services, and the regional short-haul fleet that provides truckload van service across the U.S; and Werner Logistics, which is a non-asset-based transportation and logistics provider.

Zebra Technologies designs, manufactures, and sells a range of automatic identification and data capture products, including: mobile computers, barcode scanners and imagers, radio frequency identification devices (RFID) readers, printers for barcode labeling and personal identification, real-time location systems, related accessories and supplies, such as labels and other consumables, and software utilities and applications. The company has two segments: Asset Intelligence and Tracking, which includes barcode and card printing, supplies, services, location solutions, and retail solutions; and Enterprise Visibility and Mobility, which includes mobile computing, data capture, RFID, and services.

Zynex, through its subsidiary, Zynex Medical, Inc. (ZMI), designs, manufactures and markets medical devices that treat chronic and acute pain, as well as activate and exercise muscles for rehabilitative purposes with electrical stimulation. The ZMI devices are portable, battery operated and include an electrical pulse generator which is connected to the body via electrodes. ZMI also designs, manufactures and markets the NeuroMove product. The NeuroMove contains electromyography and electric stimulation technology that is primarily used for stroke, spinal cord and traumatic brain injury rehabilitation, by reaching parts of the brain to re-connect with muscles, also known as neuroplasticity.