Abeona Therapeutics is a clinical-stage biopharmaceutical company developing cell and gene therapies for life-threatening rare genetic diseases. The company's main programs include EB-101, an autologous, gene-corrected cell therapy for recessive dystrophic epidermolysis bullosa, ABO-102, an adeno-associated virus-based gene therapy for Sanfilippo syndrome type A, and ABO-101 an AAV-based gene therapy for Sanfilippo syndrome type B. The company is also developing ABO-202 and ABO-201, which are AAV-based gene therapies for the CLN1 and CLN3 forms of Batten Disease, respectively, ABO-401 for the treatment of cystic fibrosis, and ABO-5OX for the treatment of retinal diseases.
AcelRx Pharmaceuticals is a pharmaceutical company focused on the development and commercialization of therapies for use in medically supervised settings. The company's DSUVIA? and Zalviso, are both focused on the treatment of acute pain, and each utilize sufentanil, for use in medically supervised settings. DSUVIA is indicated for use in adults in a certified medically supervised healthcare setting, such as hospitals, surgical centers, and emergency departments, for the management of acute pain severe enough to require an opioid analgesic and for which alternative treatments are inadequate. Zalviso is for the management of moderate-to-severe acute pain in hospitalized adult patients.
Applied Therapeutics is a clinical-stage biopharmaceutical company developing a pipeline of product candidates against validated molecular targets in indications of unmet medical need. The company's main product candidate, AT-007, is a central nervous system, penetrant AR inhibitor (ARI) that the company is developing for the treatment of galactosemia, a rare pediatric metabolic disease that affects how the body processes a simple sugar called galactose. The company's second product candidate, AT-001, is an ARI with systemic exposure and peripheral nerve permeability that the company is developing for the treatment of diabetic cardiomyopathy, a fatal fibrosis of the heart.
Clovis Oncology is a biopharmaceutical company focused on acquiring, developing and commercializing anti-cancer agents. The company's product Rubraca? (rucaparib), an oral small molecule inhibitor of poly ADP-ribose polymerase, is marketed in the U.S. for two indications specific to recurrent epithelial ovarian, fallopian tube or primary peritoneal cancer. In addition to Rubraca, the company has a second product candidate in clinical development. Lucitanib is an investigational, oral, potent inhibitor of the tyrosine kinase activity of vascular endothelial growth factor receptors 1 through 3, platelet-derived growth factor receptors alpha and beta and fibroblast growth factor receptors 1 through 3.
ConocoPhillips is an exploration and production company engaged in exploring for, producing, transporting and marketing crude oil, bitumen, natural gas, liquefied natural gas and natural gas liquids. The company's segments include: Alaska, which operates in Alaska; Lower 48, which operates in the United States and the Gulf of Mexico; Canada, which operates in Alberta and British Columbia; Europe and North Africa, which consists of operations and exploration activities in Norway, the United Kingdom and Libya; Asia Pacific and Middle East, which operates in China, Indonesia, Malaysia, Australia, Qatar, and Timor-Leste; and Other International, which operates in Colombia, Chile and Argentina.
Continental Resources is an independent crude oil and natural gas company engaged in the exploration, development, and production of crude oil and natural gas mainly in the North, South and East regions of the U.S. The North region consists of properties north of Kansas and west of the Mississippi River and includes North Dakota Bakken, Montana Bakken, and the Red River units. The South region includes all properties south of Nebraska and west of the Mississippi River including various plays in the South Central Oklahoma Oil Province and Sooner Trend Anadarko Canadian Kingfisher areas of Oklahoma. The East region is comprised of undeveloped leasehold acreage east of the Mississippi River.
Document Security Systems is a developer and marketer of secure document and product technologies. The company focuses on creating solutions that protect against fraud and ensure the well-being of consumers worldwide. The company does business in five operating segments as follows: DSS Packaging and Printing Group, which produces custom packaging services; DSS Plastics Group, which manufactures laminated and surface printed cards; DSS Digital Group, which researches, develops, markets and sells the company's digital products; and DSS Technology Management, which monetizes its various patent portfolios through commercial litigation and licensing.
Enanta Pharmaceuticals is a biotechnology company that creates small molecule drugs primarily for the treatment of viral infections and liver diseases. The company's wholly owned research and development programs are in virology, namely respiratory syncytial virus and hepatitis B virus, and in liver disease (non-virology), namely non-alcoholic steatohepatitis and primary biliary cholangitis. Through its Collaborative Development and License Agreement with AbbVie Inc (AbbVie), the company has discovered and out-licensed to AbbVie two protease inhibitor compounds that have been clinically tested, manufactured, and commercialized by AbbVie for the treatment of hepatitis C virus.
Farmer Bros. is a coffee roaster, wholesaler and distributor of coffee, tea and culinary products. The company's products are manufactured under supply agreements, under its owned brands, as well as under private labels on behalf of certain customers. The company's product categories consist of the following: a line of roast and ground coffee, including organic, Direct Trade, Project D.I.R.E.C.T.? and other offerings; frozen liquid coffee; flavored and unflavored iced and hot teas; culinary products and coffee-related products; spices; and other beverages. The company's primary brands include Farmer Brothers?, Artisan Collection by Farmer Brothers?, Superior?, Metropolitan?, China Mist? and Boyds?.
General Dynamics is an aerospace and defense company. The company has five operating segments: Aerospace, which provides a family of Gulfstream aircraft and services for business aircraft produced by Gulfstream and other original equipment manufacturers; Combat Systems, which provides combat vehicles, weapons systems and munitions; Information Technology, which provides information technology (IT) services, IT infrastructure modernization and professional services; Mission Systems, which provides mission-critical products and systems; and Marine Systems, which designs and builds nuclear-powered submarines, surface combatants, and auxiliary and combat-logistics ships.
Grand Canyon Education is an educational services company focused on providing support services to institutions in the post-secondary education sector. The company's services include: Technical and Academic Services, which provides services that relate to the ongoing maintenance of its client's educational infrastructure, including online course delivery and management, student records, assessment, customer relations management and other internal administrative systems; Counseling Services and Support, which includes team-based counseling and other support for prospective and existing students of its client as well as financial aid processing; Marketing and Communication; and Back Office Services.
Hanesbrands is a marketer of basic innerwear and activewear apparel in the Americas, Europe, Australia and Asia/Pacific under some apparel brands, including Hanes, Champion, Bonds, DIM, Maidenform, Bali, Playtex, Lovable, Bras N Things, Nur Die/Nur Der, Alternative, L'eggs, JMS/Just My Size, Wonderbra, and Gear for Sports. The company's segments are: Innerwear, which includes apparel products, such as men's underwear, women's panties, children's underwear, socks and intimate apparel; Activewear, which includes T-shirts, fleece, performance apparel, sport shirts and thermals; and International, which includes innerwear, activewear, hosiery and home goods products, sold outside of the United States.
HollyFrontier is a petroleum refiner that produces products such as gasoline, diesel fuel, jet fuel, other lubricant products, and specialty and modified asphalt. The company's segments are: Refining, which involves the purchase and refining of crude oil and wholesale and marketing of refined products; Lubricants and Specialty Products, which includes the production of lubricant products such as base oils, white oils, other products and finished lubricants; and the company's subsidiary, Holly Energy Partners, L.P., which owns and operates logistics and refinery assets consisting of petroleum product and crude oil pipelines, terminals, tankage, loading rack facilities and processing units.
Sanfilippo (John B.) & Son is a processor and distributor of tree nuts and peanuts. The company's principal products are raw and processed nuts. The nut product line includes almonds, pecans, peanuts, black walnuts, English walnuts, cashews, macadamia nuts, pistachios, pine nuts, Brazil nuts and filberts. The company also markets and distributes, and in various cases processes and manufactures, other food and snack products. These other products include snack mixes, salad toppings, snacks, dried fruit and chocolate and yogurt coated products; baking ingredients; bulk food products; sunflower kernels, pepitas, snack mixes, candy and confections, corn snacks, sesame sticks and other sesame snack products.
Kirby operates tank barge. The company's marine transportation segment provides marine transportation services, operating tank barges and towing vessels transporting bulk liquid products. The company transports petrochemicals, black oil, refined petroleum products and agricultural chemicals by tank barge. The company's distribution and services segment, sells genuine replacement parts, provides service mechanics to overhaul and repair engines, transmissions, reduction gears and related oilfield services equipment, rebuilds component parts or diesel engines, transmissions and reduction gears, and related equipment used in oilfield services, marine, power generation, on-highway and other industrial applications.
Oyster Point Pharma is a clinical stage biopharmaceutical company focused on the discovery, development and commercialization of first-in-class pharmaceutical therapies to treat ocular surface diseases. The company's lead product candidate OC-01 (varenicline), a highly selective nicotinic acetylcholine receptor (nAChR) agonist, is being developed as a nasal spray to treat the signs and symptoms of dry eye disease (DED). OC-01's novel mechanism of action is designed to re-establish tear film homeostasis by activating the trigeminal parasympathetic pathway and stimulating the glands and cells responsible for natural tear film production.
Pilgrims Pride is primarily engaged in the production, processing, marketing and distribution of fresh, frozen chicken products to retailers, distributors and foodservice operators. The company's primary product types are fresh chicken products, prepared chicken products and export chicken products. The company's fresh chicken products consist of refrigerated (nonfrozen) whole or cut-up chicken, either pre-marinated or non-marinated and prepackaged case-ready chicken. The company's case-ready chicken includes various combinations of freshly refrigerated, whole chickens and chicken parts in trays, bags or other consumer packs labeled and priced ready for the retail grocer's fresh meat counter.
Puma Biotechnology is a biopharmaceutical company with a focus on the development and commercialization of products to improve cancer care. The company in-licenses from Pfizer, Inc., the global development and commercialization rights to PB272 (neratinib, oral), PB272 (neratinib, intravenous) and PB357. Neratinib is an irreversible tyrosine kinase inhibitor that blocks signal transduction through the human epidermal growth factor receptors, HER1, HER2 and HER4. The company is primarily focused on the development and commercialization of the oral version of neratinib, and its drug candidates are directed at the treatment of HER2-positive breast cancer and HER2 mutated cancers.
Quad/Graphics is a marketing solutions provider. The company's United States Print and Related Services segment is comprised of its printing operations, which includes retail inserts, publications, catalogs, special interest publications, journals, direct mail, directories, in-store marketing and promotion, packaging, newspapers, custom print products, other commercial and printed products and global paper procurement, together with marketing and other complementary services. This segment also includes the manufacture of ink. The company's International segment provides printed products and marketing and other complementary services consistent with the United States Print and Related Services segment.
Raytheon Technologies is an aerospace and defense company providing systems and services for commercial, military and government customers. Collins Aerospace Systems specializes in aerostructures, avionics, interiors, mechanical systems, mission systems and power controls that serve customers across the commercial, regional, business aviation and military sectors. Pratt & Whitney designs, manufactures and services aircraft engines and auxiliary power systems for commercial, military and business aircraft. Raytheon Intelligence & Space develops sensors, training, and cyber and software solutions. Raytheon Missiles & Defense provides end-to-end solutions to detect, track and engage threats.
Soliton is a medical device company with a proprietary platform technology licensed from The University of Texas MD Anderson Cancer Center. The company's rapid acoustic pulse device uses rapid pulses of designed acoustic shockwaves to to disrupt cellular and subcellular structures in the dermis and subcutaneous tissue. The company's technology allows a doctor to treat a patient multiple times in a single office visit and reduce the overall time it takes to remove a tattoo.
Target Hospitality provides rental and hospitality services including: catering food services, maintenance, housekeeping, grounds-keeping, on-site security, overall workforce lodge management, and laundry service. The company serves clients in oil, gas, mining, alternative energy, government and immigrations sectors principally located in the West Texas, South Texas, Oklahoma and Bakken regions, as well as various linear-construction (pipeline and infrastructure) projects in the United States.
Tejon Ranch is a real estate development and agribusiness company. The company's segments are: Real Estate-Commercial/Industrial, which is involved in building, land lease activities, and land and building sales; Real Estate-Resort/Residential, which is involved in the land entitlement and development process internally and through a joint venture; mineral resources, which includes oil and gas royalty leases, rock and aggregate mining leases, a lease with National Cement and sales of water; Farming Operations, which is engaged in the sale of wine grapes, almonds and pistachios; and Ranch Operations, which consists of game management and ancillary land uses such as grazing leases and filming.
TherapeuticsMD is a women's healthcare company focused on creating and commercializing products to support women's healthcare issues for pregnancy prevention, pregnancy, childbirth, nursing, pre-menopause, and menopause. The company's solutions range from hormone therapy pharmaceutical products to patient-controlled, long-acting contraceptive. The company also manufactures and distributes branded and generic prescription prenatal vitamins under the vitaMedMD? and BocaGreenMD? brands. The company's hormone therapy drugs include: IMVEXXY? for the treatment of moderate-to-severe dyspareunia (vaginal pain associated with sexual activity); and ANNOVERA?, a one-year ring-shaped contraceptive vaginal system.
Tyme Technologies is a biotechnology company developing cancer metabolism-based therapies (CMBTs@) for a range of solid tumors and hematologic cancers. The company's primary clinical CMBT program, SM-88 (racemetyrosine), is an oral, monotherapy investigational agent, which has completed enrollment for two Phase II clinical trials in prostate and pancreatic cancer, and the company is preparing for pivotal studies for SM-88 in pancreatic cancer. In addition to SM-88, the company has a pipeline of pre-Initial New Drug Application CMBT product candidates. One candidate, TYME-18, is designed for intra-tumoral injection to increase the permeability of cancer cells.
Tyson Foods is a food company. The company's operations consist of breeding stock, contract farmers, feed production, processing, further-processing, marketing and transportation of chicken and related allied products, including animal and pet food ingredients. Through its wholly-owned subsidiary, Cobb-Vantress, Inc., the company is engaged as poultry breeding stock supplier. The company also processes live fed cattle and hogs and fabricates dressed beef and pork carcasses into primal and sub-primal meat cuts, case-ready beef and pork and fully-cooked meats. The company produces a range of fresh, frozen and refrigerated food products. The company operates in Beef, Pork, Chicken and Prepared Foods segments.
X4 Pharmaceuticals is a clinical-stage biopharmaceutical company focused on applying monoclonal antibody (mAb) immunotherapies to address serious infectious diseases. The company's Programs: ASN100 is a combination of two fully human mAbs that are co-administered intravenously to neutralize the six cytotoxins critical to S. aureus pneumonia pathogenesis; ASN500 is a mAb targeting respiratory syncytial virus, a virus that can cause serious respiratory tract infections in young children and elderly and immunocompromised patients; and the company's preclinical stage Gram-negative mAb programs, ASN300 for Klebsiella pneumoniae and ASN200 for Escherichia coli, were outlicensed to the company's subsidiary.
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