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ING Helpdesk
  • ING Helpdesk

Benelux Morning Notes

AB InBev: On Track. UCB: Galvokimig, an opportunity for long-term growth

Guy Sips ... (+5)
  • Guy Sips
  • Hilde Van Boxstael
  • Jacob Mekhael
  • Livio Luyten
  • Wim Lewi
Jacob Mekhael
  • Jacob Mekhael

UCB Galvokimig R&D call highlights potential in AD, model update

Yesterday, UCB hosted an R&D call to highlight the phase 2a data for galvokimig from EADV 2025, which showed strong efficacy in atopic dermatitis (AD), with a 52.6% placebo-adjusted EASI75 response at week 12, outperforming other biologics in cross-trial comparison. The KOL highlighted galvokimig's potential for broad positioning across the AD treatment paradigm if the early data is replicated in later stage trials, especially as a monotherapy. We update our model for UCB, which brings us to a n...

ING Helpdesk
  • ING Helpdesk

Benelux Morning Notes

Kendrion: Divests remaining automotive business. UCB: Competitor Sonelokimab fails to impress in HS

Guy Sips ... (+6)
  • Guy Sips
  • Hilde Van Boxstael
  • Jacob Mekhael
  • Mathijs Geerts Danau
  • Michiel Declercq
  • Wim Lewi
Jacob Mekhael
  • Jacob Mekhael

UCB Bimzelx competitor sonelokimab shows mixed phase 3 results in HS

In UCB related news, MoonLake Therapeutics (no coverage) reported topline phase 3 data for Bimzelx competitor, sonelokimab (IL-17A/F nanobody) in hidradenitis suppurativa (HS) that showed mixed results. Averaging both VELA-1 and VELA-2 trials brings us to a 13.5% placebo adjusted HiSCR75 response, which is lower than the 17.5% that Bimzelx showed in BE HEARD I and II, and the approx. 20% delta bar set by MoonLake's management earlier this year. Acknowledging the high placebo response in VELA-2, ...

Martial Descoutures
  • Martial Descoutures
Martial Descoutures
  • Martial Descoutures
ING Helpdesk
  • ING Helpdesk

Benelux Morning Notes

Aedifica: €21m investment in the development of 3 care homes in Finland. CTP: Highlights from 2-day CMD in Germany. dsm-firmenich: Softly does it. Prosus: Expanding the ecosystem. Randstad: Preliminary preview 3Q25F results due 22 October. TKH Group: Change is coming. UCB: Renewed tariff threat on US branded pharma unlikely to affect UCB

Guy Sips ... (+8)
  • Guy Sips
  • Hilde Van Boxstael
  • Jacob Mekhael
  • Livio Luyten
  • Mathijs Geerts Danau
  • Michiel Declercq
  • Thibault Leneeuw
  • Wim Hoste

Morning Notes : ACKB BB, COLR BB, DSFIR NA, FAGR BB, HYL BB, SEQUA BB,...

: ACKB BB, COLR BB, DSFIR NA, FAGR BB, HYL BB, SEQUA BB, TWEKA NA, DEME BB

 PRESS RELEASE

Ackermans & van Haaren invests 22 million euros in VKC Nuts

Ackermans & van Haaren invests 22 million euros in VKC Nuts Dear shareholder, Dear Madam, Dear Sir, Ackermans & van Haaren (AvH) has entered into an agreement to invest 22 million euros in VKC Nuts Private Limited (VKC Nuts), a leading family business in the fast-growing nuts and dried fruits sector in India. Upon closing of this investment, which is expected in the fourth quarter of this year, AvH will hold a 16.6% stake in VKC Nuts and be represented on its board of directors. Please find attached the full press release. Best regards Ackermans & van Haaren Attachment ...

 PRESS RELEASE

Ackermans & van Haaren investit 22 millions d'euros dans VKC Nuts

Ackermans & van Haaren investit 22 millions d'euros dans VKC Nuts Cher actionnaire, Monsieur, Madame, Ackermans & van Haaren (AvH) a conclu un accord en vue d’investir 22 millions d’euros dans VKC Nuts Private Limited (VKC Nuts), une entreprise familiale leader du marché dans le secteur en forte croissance des fruits à coque et fruits secs en Inde. À l’issue de cette opération, dont le closing est attendu au quatrième trimestre de cette année, AvH détiendra une participation de 16,6 % dans VKC Nuts et sera représentée au sein de son conseil d’administration. Veuillez trouver ci-joint l...

 PRESS RELEASE

Ackermans & van Haaren investeert 22 miljoen euro in VKC Nuts

Ackermans & van Haaren investeert 22 miljoen euro in VKC Nuts Geachte aandeelhouder, Geachte mevrouw, geachte heer, Ackermans & van Haaren (AvH) heeft een overeenkomst gesloten om 22 miljoen euro te investeren in VKC Nuts Private Limited (VKC Nuts), een toonaangevende familiale onderneming op de snelgroeiende Indiase markt voor noten en gedroogd fruit. Na afronding van deze investering, die wordt verwacht in het vierde kwartaal van dit jaar, zal AvH een belang van 16,6% verwerven in VKC Nuts en vertegenwoordigd zijn in de raad van bestuur. Gelieve bijgevoegd het volledige persbericht t...

Jacob Mekhael ... (+2)
  • Jacob Mekhael
  • Mathijs Geerts Danau

Life Sciences Conference 25 Sep 2025

KBC Securities will host its annual life sciences conference on 25 September in Brussels. The event will include 14 exciting companies, both public and private, from the BeNeLux ecosystem and beyond. In this conference note, we provide an overview of the attending companies, as well as an outlook on KBC Securities' life sciences broader coverage.

Jacob Mekhael ... (+4)
  • Jacob Mekhael
  • Thibault Leneeuw
  • Wim Hoste
  • Wim Lewi
Jacob Mekhael
  • Jacob Mekhael

UCB Bimzelx 3-year HS data R&D call takeaways

Yesterday, UCB hosted an R&D call to dive into the 3-year data for Bimzelx in hidradenitis suppurativa (HS), presented last week at EADV 2025, which showed sustained or deepening HiSCR responses. Draining tunnel count continued to decline, improving quality of life, with DLQI 0/1 responses continuing to increase up to 148 weeks. KOLs John Ingram and Amit Garg favoured Bimzelx over other therapies incl. IL-17, citing its depth of response and real-world efficacy, and highlighted the need for earl...

Jacob Mekhael
  • Jacob Mekhael

UCB Galvokimig shows strong responses in atopic dermatitis at EADV 202...

UCB announced new 12-week efficacy and 18-week safety data from the phase 1/2a first-in-patient trial for galvokimig (IL-13, IL-17A and IL-17F antibody) in moderate-to-severe atopic dermatitis, to be presented at EADV 2025. The results showed a 52.6% placebo adjusted response on the primary endpoint of =75% improvement from baseline in Eczema Area and Severity Index (EASI75). We view this as competitive compared to other phase 2 trials in atopic dermatitis, and highlight competitor Dupixent's $ ...

Guy Sips ... (+7)
  • Guy Sips
  • Hilde Van Boxstael
  • Jacob Mekhael
  • Livio Luyten
  • Lynn Hautekeete
  • Mathijs Geerts Danau
  • Michiel Declercq
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