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Martial Descoutures ... (+2)
  • Martial Descoutures
  • Oussema Denguir

Cellectis : Cellectis: the reference player in allogeneic CAR-T cells

Cellectis is the French specialist in allogeneic CAR-T cells, now mainly developed in cancer treatment. Its first CAR-T in partnership with Servier and Allogene is currently in the pivot phase in first-line diffuse B-cell lymphoma, while its most advanced own CAR-T candidate is expected to enter into the pivot phase II in H2 this year in acute lymphoblastic leukaemia. Bolstered by a recent deal with AstraZeneca, which acquired a stake in the company (+44%), we are initiating coverage of the stoc...

Martial Descoutures ... (+2)
  • Martial Descoutures
  • Oussema Denguir

Cellectis : Cellectis : l’acteur de référence des CAR-T allogéniques

Cellectis est le spécialiste français des CAR-T allogéniques, développés aujourd’hui essentiellement dans le traitement des cancers. Son premier CAR-T partenarisé à Servier et Allogene est actuellement en phase pivot en 1ere L du lymphome diffus à cellules B alors que son candidat CAR-T propre le plus avancé devrait entrer en phase 2 pivot au S2 de cette année en Leucémie Lymphoïde Aigue. Fort d’un accord récent avec AstraZeneca qui a pris une participation dans la société (44%), nous initions l...

Guy Sips ... (+11)
  • Guy Sips
  • Jacob Mekhael
  • Kristof Samoy
  • Lynn Hautekeete
  • Michiel Declercq
  • Sharad Kumar S.P
  • Thibault Leneeuw
  • Thomas Couvreur
  • Thomas Vranken
  • Wim Hoste
  • Wim Lewi

US Tariffs Navigating the impact on Benelux equities

Trumps reciprocal tariffs caused a massive blow to equity markets, following a pressured period of escalating trade wars. Retaliatory measures can further heavily damage market confidence, as seen Friday when China announced their 34% tarrif of US goods. International trade policies have never moved this erratic and untransparant, with uncertainty and volatility being the baseline for now. In this report we highlight the key stocks in our coverage relevant to this discussion.

 PRESS RELEASE

Monthly information on share capital and company voting rights

Monthly information on share capital and company voting rights (Article 223-16 of General Regulation of the French financial markets authority) PARIS, April 07, 2025 (GLOBE NEWSWIRE) -- Listing market: Euronext Growth ISIN code: FR0010425595 DateTotal number of sharesin the capitalTotal number of voting rights03/31/2025100,290,07889,046,759 For further information on Cellectis, please contact:      Media contacts:        Pascalyne Wilson, Director, Communications, +33 (0)7 76 99 14 33, Patricia Sosa Navarro, Chief of Staff to the CEO, +33 (0)7 76 77 46 93 Investor Relations co...

 PRESS RELEASE

Information mensuelle relative au nombre total des droits de vote et d...

Information mensuelle relative au nombre total des droits de vote et d’actions composant le capital social (Article 223-16 du Règlement Général de l’Autorité des Marchés Financiers) PARIS, 07 avr. 2025 (GLOBE NEWSWIRE) -- Place de cotation : Euronext Growth ISIN code: FR0010425595 DateNombre total d’actionscomposant le capital socialNombre total de droits de vote31/03/2025100 290 07889 046 759 Pour de plus amples informations sur Cellectis, veuillez contacter :         Contacts média :         Pascalyne Wilson, Director, Communications, +33 (0)7 76 99 14 33, Patr...

 PRESS RELEASE

CRISPR Therapeutics to Present at the 24th Annual Needham Virtual Heal...

CRISPR Therapeutics to Present at the 24th Annual Needham Virtual Healthcare Conference ZUG, Switzerland and BOSTON, April 03, 2025 (GLOBE NEWSWIRE) -- CRISPR Therapeutics (Nasdaq: CRSP), a biopharmaceutical company focused on creating transformative gene-based medicines for serious diseases, today announced that members of its senior management team will present at the 24th Annual Needham Virtual Healthcare Conference on Tue, April 8 at 12:45 p.m. ET. A live webcast of the fireside chat will be available on the "Events & Presentations" page in the Investors section of the Company's webs...

 PRESS RELEASE

Autolus Therapeutics to Participate in the 24th Annual Needham Virtual...

Autolus Therapeutics to Participate in the 24th Annual Needham Virtual Healthcare Conference LONDON, April 02, 2025 (GLOBE NEWSWIRE) -- Autolus Therapeutics plc (Nasdaq: AUTL), an early commercial-stage biopharmaceutical company developing, manufacturing and delivering next-generation programmed T cell therapies, announces that the Company will participate in the 24th Annual Needham Virtual Healthcare Conference. Autolus Chief Executive Officer Dr. Christian Itin will present in a Fireside Chat on Wednesday, April 9, 2025 at 9:30am EDT / 14:30pm BST. A webcast of the fireside chat will ...

 PRESS RELEASE

Autolus Therapeutics to Host R&D Investor Event on Wednesday, April 23...

Autolus Therapeutics to Host R&D Investor Event on Wednesday, April 23, 2025 LONDON, April 01, 2025 (GLOBE NEWSWIRE) -- Autolus Therapeutics plc (Nasdaq: AUTL), an early commercial-stage biopharmaceutical company developing, manufacturing and delivering next-generation programmed T cell therapies, announced that the Company will host an R&D investor event on Wednesday, April 23, 2025 at 8:30am EDT / 13:30pm BST. Autolus will present an update on clinical pipeline programs, including plans to expand the obe-cel opportunity. The Company expects to report initial data in six patients from...

 PRESS RELEASE

CRISPR Therapeutics Announces Transition of Chief Operating Officer

CRISPR Therapeutics Announces Transition of Chief Operating Officer ZUG, Switzerland and BOSTON, March 26, 2025 (GLOBE NEWSWIRE) -- CRISPR Therapeutics (Nasdaq: CRSP), a biopharmaceutical company focused on creating transformative gene-based medicines for serious diseases, today announced that its Chief Operating Officer, Julianne Bruno, will be stepping down from the Company to pursue external opportunities, effective as of April 11, 2025. “Julie has been an invaluable member of our leadership team over the last six years. Her leadership has been instrumental in successfully advancing o...

Jacob Mekhael
  • Jacob Mekhael

Autolus FIRST LOOK: FY24 results hold no surprises, upcoming R&D day

Yesterday before US market opens, Autolus reported unsurprising FY24 results with a cash position of $ 588m (YE23: $ 239.6m), sufficient to drive Aucatzyl's (obe-cel, CD19 CAR-T) launch in r/r adult ALL, and advance the company's pipeline towards pivotal autoimmune data. While the company did not share sales figures/patients dosed with Aucatzyl in the US (1Q25 sales figures to be communicated during the quarterly update), management confirmed that the launch is tracking well compared to their ex...

Hilde Van Boxstael ... (+5)
  • Hilde Van Boxstael
  • Jacob Mekhael
  • Sharad Kumar S.P
  • Thomas Couvreur
  • Wim Lewi
 PRESS RELEASE

Autolus Therapeutics Reports Fourth Quarter and Full Year 2024 Financi...

Autolus Therapeutics Reports Fourth Quarter and Full Year 2024 Financial Results and Business Updates AUCATZYL® (obecabtagene autoleucel) U.S. commercial launch progressing on track with 33 authorized treatment centers as of March 19, 2025, following US FDA approval on November 8, 2024Obe-cel MHRA and EMA marketing authorizations expected in H2 2025Initial six patients dosed in Phase 1 dose confirmation trial in Systemic Lupus Erythematosus (SLE) Company to provide clinical development program updates, including plans for expansion in autoimmune diseases, at R&D investor event to be held on...

 PRESS RELEASE

Cellectis publie ses résultats financiers du quatrième trimestre 2024 ...

Cellectis publie ses résultats financiers du quatrième trimestre 2024 et de l’exercice 2024 et une mise à jour de ses activités ○ UCART22 : présentation des données de Phase 1 et de la stratégie de développement prévues au troisième trimestre 2025. Statuts de médicament orphelin et de médicament pour une maladie pédiatrique rare accordés par la FDA et statut de médicament orphelin accordé par la Commission européenne à UCART22 pour le traitement de la LLA ○ UCART20x22 : essai clinique de Phase 1 en cours dans le lymphome non Hodgkinien à cellules B en rechute ou réfractaire. Présentati...

 PRESS RELEASE

Cellectis Reports Financial Results for the Fourth Quarter and Full Ye...

Cellectis Reports Financial Results for the Fourth Quarter and Full Year 2024 and Provides a Business Update ○ UCART22 Phase 1 dataset and late-stage development strategy expected in the third quarter of 2025; Orphan Drug Designation (ODD) and Rare Pediatric Disease Designation (RPDD) granted by FDA and ODD granted by the European Commission to UCART22 for the treatment of ALL. ○ UCART20x22 Phase 1 study in relapsed or refractory B-cell non-Hodgkin lymphoma (r/r NHL) ongoing with readout expected in late 2025. ○ AstraZeneca partnership: R&D activities ongoing on three programs – one allog...

Research Team ACF
  • Research Team ACF

ACF Thematic Research Regenerative Medicine Diabetes Treatment & Innov...

Diabetes mellitus, Type 1 (T1D) and Type 2 (T2D, 85-90% of cases), is a USD ~75bn global therapy market. Global economic costs of diabetes may exceed USD1 trn today and USD 450bn in the US, suggesting a pressing global health challenge. Diabetes is a chronic metabolic disorder characterized by high blood sugar levels. In 2024, consensus global estimates suggested there were ~800m adult diabetes sufferers. In 2021, according to the IDF there >530m sufferers globally. For 2027E we modestly forecas...

 PRESS RELEASE

Cellectis to Report Fourth Quarter and Full Year 2024 Financial Result...

Cellectis to Report Fourth Quarter and Full Year 2024 Financial Results on March 13, 2025 NEW YORK, March 07, 2025 (GLOBE NEWSWIRE) -- Cellectis (the “Company”) (Euronext Growth: ALCLS- NASDAQ: CLLS), a clinical-stage biotechnology company using its pioneering gene-editing platform to develop life-saving cell and gene therapies, today announced that it will report financial results for the fourth quarter and full year 2024 ending December 31, 2024 on Thursday, March 13, 2025 after the close of the US market. The publication will be followed by an investor conference call and webcast...

 PRESS RELEASE

Cellectis publiera ses résultats financiers du quatrième trimestre et...

Cellectis publiera ses résultats financiers du quatrième trimestre et de l’année 2024 le 13 mars 2025 NEW YORK, 07 mars 2025 (GLOBE NEWSWIRE) -- Cellectis (Euronext Growth: ALCLS - Nasdaq: CLLS), société de biotechnologie de stade clinique qui utilise sa plateforme pionnière d’édition du génome pour développer des thérapies cellulaires et géniques, publiera ses résultats financiers pour le quatrième trimestre et l’exercice 2024 clos au 31 décembre 2024, le jeudi 13 mars 2025 après la clôture du marché aux États-Unis. Une conférence téléphonique se tiendra vendredi 14 mars 2025 à 13h00 h...

 PRESS RELEASE

Monthly information on share capital and company voting rights

Monthly information on share capital and company voting rights (Article 223-16 of General Regulation of the French financial markets authority) PARIS, March 06, 2025 (GLOBE NEWSWIRE) -- Listing market: Euronext Growth ISIN code: FR0010425595 DateTotal number of sharesin the capitalTotal number of voting rights02/28/2025100,093,87388,849,752 For further information on Cellectis, please contact:      Media contacts:        Pascalyne Wilson, Director, Communications, +33 (0)7 76 99 14 33, Patricia Sosa Navarro, Chief of Staff to the CEO, +33 (0)7 76 77 46 93 Investor Relations cont...

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