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Jacob Mekhael
  • Jacob Mekhael

Galapagos GLPG3667 phase 2 hits topline in DM, but misses in SLE

Galapagos announced the topline results from 2 phase 2 studies evaluating the efficacy and safety of GLPG3667 (TYK2 inhibitor) in dermatomyositis (DM, GALARISSO study) and active systemic lupus erythematosus (SLE, GALACELA study). The GALARISSO study in DM met its primary endpoint showing a 14.26 delta on the TIS measure at 24 weeks, which compares favourably to brepocitinib (TYK2/JAK1 inhibitor) in our view. In the GALACELA study in SLE patients, primary endpoint at 32 weeks was not met, but fi...

Guy Sips ... (+8)
  • Guy Sips
  • Hilde Van Boxstael
  • Jacob Mekhael
  • Kristof Samoy
  • Livio Luyten
  • Michiel Declercq
  • Thibault Leneeuw
  • Wim Lewi

Morning Notes : BAR BB, COFB BB, FAGR BB, GLPG NA, IBAB BB, DEME BB, N...

: BAR BB, COFB BB, FAGR BB, GLPG NA, IBAB BB, DEME BB, NXFIL NA, ENRGY BB

 PRESS RELEASE

Galapagos Announces Topline Results from Two Phase 3-Enabling Studies ...

Galapagos Announces Topline Results from Two Phase 3-Enabling Studies with Selective TYK2 Inhibitor GLPG3667 in Dermatomyositis and Systemic Lupus Erythematosus GLPG3667 met primary endpoint in dermatomyositis study, demonstrating a statistically significant clinical benefit and meaningful improvements on secondary measures of disease activity compared to placebo In the systemic lupus erythematosus study, GLPG3667 delivered numerical improvements on several secondary endpoints compared to placebo but did not achieve statistical significance in primary endpoint analysis The safety profile ...

 PRESS RELEASE

Galapagos maakt topline resultaten bekend van twee fase 3-enabling stu...

Galapagos maakt topline resultaten bekend van twee fase 3-enabling studies met selectieve TYK2-remmer GLPG3667 bij dermatomyositis en systemische lupus erythematodes GLPG3667 bereikte het primaire eindpunt in de dermatomyositis-studie en toonde een statistisch significant klinisch voordeel en betekenisvolle verbeteringen aan op secundaire eindpunten van ziekteactiviteit in vergelijking met placebo In de studie naar systemische lupus erythematodes leverde GLPG3667 numerieke verbeteringen op voor verschillende secundaire eindpunten in vergelijking met placebo, maar bereikte het geen statisti...

 PRESS RELEASE

Voting results of the Fiscal 2025 Annual General Meeting of Pluxee

Voting results of the Fiscal 2025 Annual General Meeting of Pluxee Voting results of the Fiscal 2025 Annual General Meeting of Pluxee Amsterdam-Schiphol, December 17, 2025 // Pluxee N.V. (“Pluxee”) held today its Annual General Meeting of Shareholders, in Amsterdam-Schipol, chaired by Didier Michaud-Daniel, Executive Chair of Pluxee’s Board of Directors. All resolutions on the agenda were approved by the shareholders. This included the adoption of the financial statements for the fiscal year which ended on August 31, 2025 (“Fiscal 2025”), and of the dividend distribution for Fiscal 2025 ...

 PRESS RELEASE

Résultats des votes de l’Assemblée générale annuelle des actionnaires ...

Résultats des votes de l’Assemblée générale annuelle des actionnaires pour l’exercice 2025 Résultats des votes de l’Assemblée générale annuelle des actionnaires pour l’exercice 2025 Amsterdam-Schiphol, 17 décembre 2025 // Pluxee N.V. (« Pluxee ») a tenu aujourd’hui son Assemblée générale annuelle à Amsterdam-Schiphol, sous la présidence de Didier Michaud-Daniel, Président Exécutif du Conseil d’Administration de Pluxee. Toutes les résolutions à l’ordre du jour ont été approuvées par les actionnaires. Cela inclut l’adoption des états financiers de l’exercice clos le 31 août 2025 (« Exercice...

 PRESS RELEASE

DISCLOSURE FISCAL 2026/06 OF TRANSACTIONS ON TREASURY SHARES

DISCLOSURE FISCAL 2026/06 OF TRANSACTIONS ON TREASURY SHARES Regulated information Paris, December 15, 2025 DISCLOSURE FISCAL 2026/06 OF TRANSACTIONS ON TREASURY SHARES  Period of: December 8 to December 12, 2025 Issuer: Pluxee N.V. Class of Securities: Ordinary shares (ISIN NL0015001W49)  Aggregate presentation by day and by market. Issuer CodeTransaction dateISIN CodeDaily total volume (in number of shares)Daily weighted average price of shares acquiredPlatform213800RQNIQT48SEEO851-Dec-25NL0015001W4930 84913,6928XPAR213800RQNIQT48SEEO851-Dec-25NL0015001W4918 01413,6681DXE213800RQNI...

 PRESS RELEASE

DECLARATION EXERCICE 2026/06 DES TRANSACTIONS SUR ACTIONS PROPRES

DECLARATION EXERCICE 2026/06 DES TRANSACTIONS SUR ACTIONS PROPRES Information réglementée  Paris, 15 décembre 2025  DECLARATION EXERCICE 2026/06 DES TRANSACTIONS SUR ACTIONS PROPRES  Période du : 8 décembre au 12 décembre 2025  Emetteur : Pluxee N.V.  Catégorie de titres : Actions ordinaires (ISIN : NL0015001W49)  Présentation agrégée par jour et par marché. Code Identifiant de l'émetteur Jour de la transaction Code identifiant de l'instrument financier Volume total journalier (en nombre d'actions) Prix pondéré moyen journalier d'acquisition des action...

 PRESS RELEASE

DISCLOSURE FISCAL 2026/05 OF TRANSACTIONS ON TREASURY SHARES 

DISCLOSURE FISCAL 2026/05 OF TRANSACTIONS ON TREASURY SHARES  Regulated information Paris, December 8, 2025 DISCLOSURE FISCAL 2026/05 OF TRANSACTIONS ON TREASURY SHARES  Period of: December 1 to December 5, 2025 Issuer: Pluxee N.V. Class of Securities: Ordinary shares (ISIN NL0015001W49)  Aggregate presentation by day and by market. Issuer CodeTransaction dateISIN CodeDaily total volume (in number of shares)Daily weighted average price of shares acquiredPlatform213800RQNIQT48SEEO851-Dec-25NL0015001W4930,84913.6928XPAR213800RQNIQT48SEEO851-Dec-25NL0015001W4918,01413.6681DXE213800RQNIQT...

 PRESS RELEASE

DECLARATION EXERCICE 2026/05 DES TRANSACTIONS SUR ACTIONS PROPRES 

DECLARATION EXERCICE 2026/05 DES TRANSACTIONS SUR ACTIONS PROPRES  Information réglementée  Paris, 8 décembre 2025  DECLARATION EXERCICE 2026/05 DES TRANSACTIONS SUR ACTIONS PROPRES  Période du : 1 décembre au 5 décembre 2025  Emetteur : Pluxee N.V.  Catégorie de titres : Actions ordinaires (ISIN : NL0015001W49)  Présentation agrégée par jour et par marché. Code Identifiant de l'émetteurJour de la transactionCode identifiant de l'instrument financierVolume total journalier (en nombre d'actions)Prix pondéré moyen journalier d'acquisition des actionsMarché213800RQNIQT48SEEO851-Dec-25NL0...

Hilde Van Boxstael ... (+6)
  • Hilde Van Boxstael
  • Mathijs Geerts Danau
  • Michiel Declercq
  • Thomas Couvreur
  • Wim Hoste
  • Wim Lewi
 PRESS RELEASE

Galapagos Presented New ATALANTA-1 Cell Therapy Data in MCL at ASH 202...

Galapagos Presented New ATALANTA-1 Cell Therapy Data in MCL at ASH 2025 High complete response rates and minimal residual disease (MRD) negativity, with durable responses, in high-risk mantle cell lymphoma (MCL) with GLPG5101, a fresh, early memory-enriched CAR T-cell therapy with a 7-day vein-to-vein time Mechelen, Belgium; December 8, 2025, 07:30 CET; Galapagos NV (Euronext & NASDAQ: GLPG) announced new and updated Phase 2 data from the ongoing ATALANTA-1 study with its CD19 CAR T-cell therapy candidate, GLPG5101, during an oral presentation (#662) at the 67th American Society of Hematol...

 PRESS RELEASE

Galapagos presenteerde nieuwe ATALANTA-1 celtherapiedata in MCL op ASH...

Galapagos presenteerde nieuwe ATALANTA-1 celtherapiedata in MCL op ASH 2025 Hoge percentages complete respons en minimale residuele ziekte (MRD)-negativiteit, met duurzame responsen, bij hoog-risico mantelcellymfoom (MCL) met GLPG5101, een verse, early-memory verrijkte CAR T-celtherapie met een vein-to-vein-tijd van 7 dagen Mechelen, België; 8 december 2025, 07:30 CET; Galapagos NV (Euronext & NASDAQ: GLPG) kondigde nieuwe en geüpdatete fase 2-gegevens aan uit de lopende ATALANTA-1-studie met haar CD19 CAR T-celtherapiekandidaat GLPG5101, tijdens een mondelinge presentatie (#662) op de 67s...

 PRESS RELEASE

DECLARATION EXERCICE 2026/04 DES TRANSACTIONS SUR ACTIONS PROPRES 

DECLARATION EXERCICE 2026/04 DES TRANSACTIONS SUR ACTIONS PROPRES  Information réglementée  Paris, 1er décembre 2025  DECLARATION EXERCICE 2026/04 DES TRANSACTIONS SUR ACTIONS PROPRES  Période du : 24 novembre au 28 novembre 2025  Emetteur : Pluxee N.V.  Catégorie de titres : Actions ordinaires (ISIN : NL0015001W49)  Présentation agrégée par jour et par marché. Code Identifiant de l'émetteur Jour de la transaction Code identifiant de l'instrument financier Volume total journalier (en nombre d'actions) Prix pondéré moyen journalier d'acquisition des acti...

 PRESS RELEASE

DISCLOSURE FISCAL 2026/04 OF TRANSACTIONS ON TREASURY SHARES 

DISCLOSURE FISCAL 2026/04 OF TRANSACTIONS ON TREASURY SHARES  Regulated information Paris, December 1, 2025 DISCLOSURE FISCAL 2026/04 OF TRANSACTIONS ON TREASURY SHARES  Period of: November 24 to November 28, 2025 Issuer: Pluxee N.V. Class of Securities: Ordinary shares (ISIN NL0015001W49)  Aggregate presentation by day and by market. Issuer CodeTransaction dateISIN CodeDaily total volume (in number of shares)Daily weighted average price of shares acquiredPlatform213800RQNIQT48SEEO8524-Nov-25NL0015001W4929 57013,9068XPAR213800RQNIQT48SEEO8524-Nov-25NL0015001W4916 02313,8655DXE213800RQ...

Bruno Cavalier ... (+2)
  • Bruno Cavalier
  • Jerôme Bodin
MC LVMH MOET HENNESSY LOUIS VUITTON SE
LI KLEPIERRE SA
COV COVIVIO SA
GFC GECINA SA
NXI NEXITY SA CLASS A
UHR SWATCH GROUP LTD. BEARER
RMS HERMES INTERNATIONAL SCA
GYC GRAND CITY PROPERTIES SA
MERY MERCIALYS SA
EL ESSILORLUXOTTICA SA
INEA FONCIERE INEA
VIV VIVENDI SE
WHA WERELDHAVE N.V.
BLND BRITISH LAND COMPANY PLC
BRBY BURBERRY GROUP PLC
LPE LAURENT-PERRIER SA
KOF KAUFMAN & BROAD SA
KER KERING SA
ALTA ALTAREA SCA
VNA VONOVIA SE
XIOR XIOR STUDENT HOUSING N.V.
ICAD ICADE SA
01913 PRADA S.P.A.
BYG BIG YELLOW GROUP PLC
UTG UNITE GROUP PLC
COFB COFINIMMO SA
COR CORTICEIRA AMORIM SGPS SA
CAI CA IMMOBILIEN ANLAGEN AG
TEG TAG IMMOBILIEN AG
VASTB VASTNED RETAIL BELGIUM NV
PSPN PSP SWISS PROPERTY AG
UBS UBM DEVELOPMENT AG
SPSN SWISS PRIME SITE AG
PAT PATRIZIA AG
MONT MONTEA SCA
AED AEDIFICA SA
CARM CARMILA SAS
LEG LEG IMMOBILIEN AG
MONC MONCLER SPA
CPINV CARE PROPERTY INVEST SA
EUR EUROCASH S.A.
SAFE SAFESTORE HOLDINGS PLC
ARG ARGAN SA
VGP VGP NV
BC BRUNELLO CUCINELLI S.P.A.
CFR COMPAGNIE FINANCIERE RICHEMONT SA
COL INMOBILIARIA COLONIAL SOCIMI SA
DIC DIC ASSET AG
FACC FACC AG
MERLIN MERLIN PROPERTIES SOCIMI S.A.
HOME NEINOR HOMES SA
AT1 AROUNDTOWN SA
LAND LAND SECURITIES GROUP PLC
MVC METROVACESA SA
NSI NSI N.V.
ULA UNIBAIL-RODAMCO-WESTFIELD SE STAPLED SECS CONS OF 1 SH UNIBAIL RODAMCO + 1 SH WFD UNIB ROD
INS INSTONE REAL ESTATE GROUP AG
AEDAS AEDAS HOMES SA
WDP WAREHOUSES DE PAUW SCA
ECMPA EUROCOMMERCIAL PROPERTIES NV
ZGN ERMENEGILDO ZEGNA NV
CTPNV CTP NV
TTS TRANSPORT TRADE SVCS
SHUR SHURGARD SELF STORAGE LIMITED
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